Efficient grid treatment of the ionization dynamics of laser-driven H-2(+)

We implement a parallel, time-dependent hybrid finite-difference Lagrange mesh code to model the electron dynamics of the fixed-nuclei hydrogen molecular ion subjected to intense ultrashort laser Pulses, Ionization rates are calculated and compared with results from a previous finite-difference approach and also with published Floquet results. The sensitivity of the results to the gauge describing the electron-field interaction is studied. Visualizations of the evolving wave packets are also presented in which the formation of a stable bound-state resonance is observed.

An Innovative Approach to Evaluating Organisational Change

This paper addresses the difficult problem of how to improve the process of evaluating organisational change. Given that the data emergent from an evaluative exercise will strongly influence the subsequent strategic and operational decisions taken by organisational managers, it is critical that the evaluation approach itself is capable of delivering high quality, accurate and timely data. The aim of this paper is to examine the role of the IT-based Optionfinder Technology used in conjunction with focus groups, in generating management decision-making data, and reflecting the changes in key performance indicators in a utility organisation. The case study research evaluates the innovative integrative approach adopted by the utility organisation and concludes that the proposed approach contributes to improvements in the decision-making capability of managers.

Ascertainment of cause-specific mortality in COPD - operations of the TORCH clinical endpoint Committee

Background: TORCH (Towards a Revolution in COPD Health) is an international multicentre, randomised, placebo-controlled clinical trial of inhaled fluticasone propionate/salmeterol combination treatment and its monotherapy components for maintenance treatment of moderately to severely impaired patients with chronic obstructive pulmonary disease (COPD). The primary outcome is all-cause mortality. Cause-specific mortality and deaths related to COPD are additional outcome measures, but systematic methods for ascertainment of these outcomes have not previously been described. Methods: A Clinical Endpoint Committee (CEC) was tasked with categorising the cause of death and the relationship of deaths to COPD in a systematic, unbiased and independent manner. The key elements of the operation of the committee were the use of predefined principles of operation and definitions of cause of death and COPD-relatedness; the independent review of cases by all members with development of a consensus opinion; and a substantial infrastructure to collect medical information. Results: 911 deaths were reviewed and consensus was reached in all. Cause-specific mortality was: cardiovascular 27%, respiratory 35%, cancer 21%, other 10% and unknown 8%. 40% of deaths were definitely or probably related to COPD. Adjudications were identical in 83% of blindly re-adjudicated cases ( = 0.80). COPD-relatedness was reproduced 84% of the time ( = 0.73). The CEC adjudication was equivalent to the primary cause of death recorded by the site investigator in 52% of cases. Conclusion: A CEC can provide standardised, reliable and informative adjudication of COPD mortality that provides information which frequently differs from data collected from assessment by site investigators.

Dynamic Job Scheduling on the Grid Environment using the Great Deluge Algorithm

The utilization of the computational Grid processor network has become a common method for researchers and scientists without access to local processor clusters to avail of the benefits of parallel processing for compute-intensive applications. As a result, this demand requires effective and efficient dynamic allocation of available resources. Although static scheduling and allocation techniques have proved effective, the dynamic nature of the Grid requires innovative techniques for reacting to change and maintaining stability for users. The dynamic scheduling process requires quite powerful optimization techniques, which can themselves lack the performance required in reaction time for achieving an effective schedule solution. Often there is a trade-off between solution quality and speed in achieving a solution. This paper presents an extension of a technique used in optimization and scheduling which can provide the means of achieving this balance and improves on similar approaches currently published.

WEBCOM-G: A candidate middleware for Grid-Ireland

WebCom-G is a fledgling Grid Operating System, designed to provide independent service access through interoperability with existing middlewares. It offers an expressive programming model that automatically handles task synchronisation – load balancing, fault tolerance, and task allocation are handled at the WebCom-G system level – without burdening the application writer. These characteristics, together with the ability of its computing model to mix evaluation strategies to match the characteristics of the geographically dispersed facilities and the overall problem- solving environment, make WebCom-G a promising grid middleware candidate.