Mesenchymal stem cells in immunoregulation

Mesenchymal stem cells (MSCs) reside within the bone marrow cavity and serve as a reservoir for the continuous renovation of various mesenchymal tissues. Recent efforts suggest that MSCs modulate the immune reactions in vitro and escape the immune surveillance in vivo. We provide herein a discussion of the issues including the current research progress on the in vitro interactions of MSCs with multiple subsets of immune cells (dendritic cells, T cells, B cells and natural killer cells), in vivo transplantation outcomes, the possible underlying mechanisms, future research directions as well as potential clinical implications.

Quantum-state transfer in imperfect artificial spin networks

High-fidelity quantum computation and quantum state transfer are possible in short spin chains. We exploit a system based on a dispersive qubit-boson interaction to mimic XY coupling. In this model, the usually assumed nearest-neighbor coupling is no longer valid: all the qubits are mutually coupled. We analyze the performances of our model for quantum state transfer showing how preengineered coupling rates allow for nearly optimal state transfer. We address a setup of superconducting qubits coupled to a microstrip cavity in which our analysis may be applied.

Reinforced Stone Columns in Weak Deposits – A Laboratory Model Study

This paper investigates the performance of stone columns in a weak deposit such as peat. It evaluates the effects of reinforcing stone columns by jacketing with a tubular wire mesh and bridging reinforcement with a metal rod and a concrete plug. A series of plate loading tests was conducted on isolated stone columns installed in a soil bed consisting of a peat layer sandwiched between two layers of sand. The load–displacement characteristics of footings supported by stone columns were investigated by applying load to a circular plate supported on: (a) untreated soil; (b) soil treated with stone columns; and (c) soil treated with stone columns reinforced with the above reinforcing techniques. The work has shown that the settlement characteristics of the soil can be improved by installing stone columns and that a significant enhancement in the load–settlement response is achieved when the columns are reinforced by the various methods.