Tuberculosis

Tuberculosis is a term that encompasses various diseases caused by bacteria of the Mycobacterium tuberculosis complex, including M tuberculosis, M bovis, M africanum, and other mycobacterial species. Whereas M tuberculosis infection is largely spread from human to human, M bovis infection has been identified as a zoonotic disease with most cases of human infection attributable to animal sources. The mycobacteria other than tuberculosis complex (MOTT), which includes M avium subsp avium and M avium subsp intracellulare isolated from animals, has been isolated from immune-compromised humans (ie, those with human immunodeficiency virus [HIV] infection), but seldom from immunocompetent humans. Recently, there has been increased interest among public health officials in drug-resistant strains of M tuberculosis, M bovis, and M avium because several have been isolated from HIV-infected and nonimmuno-compromised humans.

A Preliminary Note on Trichinosis Investigations in Alaska

Trichinosis in the arctic regions of the world has received considerable attention during recent years, particularly since the work of Roth (1948) in Greenland. In Connell's (1949) review of arctic trichinosis some Alaskan and Canadian records were included but, until now, little has been known of the status of the disease in Alaska. Information available at the present time indicates that the incidence of trichinosis is high in circumpolar carnivores and that marine mammals have a definite place in its epizootiology. Present knowledge cannot explain the survival of trichinosis in marine mammal populations, but it is evident that they may serve as important sources of human infection. Up to the present time the following mammals from Alaska have been found to be infected: From the arctic coast-polar bear, Thalarctas maritimus; arctic fox, Alapex lagapus irmuitus; red fox, Vulpes fulva alascemis; white whale, Delphinapterus leucas; Eskimo dog. From south of the Brooks Range--brown and grizzly bears, Ursus spp.; wolf, Canis lupus ssp.; wolverine. Gula l. luscus. At the time of writing, nearly ail species of land carnivores in Alaska have been examined as well as many other mammalian species less likely to be infected, including various rodents, shrews, and others.