The s-process nucleosynthesis

Theoretical as well as observational aspects of the s-process nucleosynthesis are reviewed. The classical site-independent s-process model as well as the s-process in massive stars are shortly described. A special attention is paid to the nucleosynthesis taking place in AGB stars and the extra-mixing invoked to explain the production of neutrons in the C-rich layers during the interpulse. We also discuss the nucleosynthesis found in hot AGB stars for which the s-process during the interpulse phase is inhibited, but the one resulting from the large temperatures in the thermal pulse is boosted. We comment on the uncertainties affecting our understanding of the physical mechanisms responsible for a successful s-process. Finally, various types of spectroscopic observations of s-process elements are discussed. © 2005 International Astronomical Union.

Clinical practice guideline on diagnosis and treatment of hyponatraemia

Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fuid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life threatening, and is associated with increased mortality, morbidity and length of hospital stay in patients presenting with a range of conditions. Despite this, the management of patients remains problematic. The prevalence of hyponatraemia in widely different conditions and the fact that hyponatraemia is managed by clinicians with a broad variety of backgrounds have fostered diverse institution-and speciality-based approaches to diagnosis and treatment. To obtain a common and holistic view, the European Society of Intensive Care Medicine (ESICM), the European Society of Endocrinology (ESE) and the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA), represented by European Renal Best Practice (ERBP), have developed the Clinical Practice Guideline on the diagnostic approach and treatment of hyponatraemia as a joint venture of three societies representing specialists with a natural interest in hyponatraemia. In addition to a rigorous approach to methodology and evaluation, we were keen to ensure that the document focused on patient-important outcomes and included utility for clinicians involved in everyday practice.