6 resultados para Antígenos HLA-G

em DI-fusion - The institutional repository of Université Libre de Bruxelles


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Édition d'une étiquette de momie portant un texte en copte.

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The immobilisation of molybdate on Mg,Al-LDH leads to an active, heterogeneous catalyst that generates singlet molecular oxygen from hydrogen peroxide in the absence of soluble base

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info:eu-repo/semantics/published

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The highly polymorphic fourth component of human complement (C4) is usually encoded by two genes, C4A and C4B, adjacent to the 21-hydroxylase (21-OH) genes and is also remarkable by the high frequency of the null alleles, C4A*Q0 and C4B*Q0. Complete C4 deficiency is exceptional because this condition appears only in homozygotes for the very rare double-null haplotype C4AQ0,BQ0. This condition in most cases gives rise to systemic lupus erythematosus and an increased susceptibility to infections. The molecular basis for complete C4 deficiency has not yet been established. Therefore we studied the DNA of three previously described C4 deficient patients belonging to unrelated families by restriction fragment length polymorphism analysis using C4 and 21-OH probes. These studies revealed a deletion of the C4B and 21-OHA genes in two patients and no deletion at all in the third patient. Therefore, complete C4 deficiency as a result of homozygosity for the C4AQ0, BQ0 haplotype is not a consequence of a deletion of the C4 genes. The molecular basis of this genetic abnormality is certainly very complex and may vary also from one case to another.

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info:eu-repo/semantics/nonPublished