2 resultados para Polis

em Biblioteca Digital da Produção Intelectual da Universidade de São Paulo


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The cooperation and the sharing of information cataloguing and bibliographical in environment automated, this was only possible with the creation and adoption of interchange format MARC21. But due to the progresses of the technologies of information and communication, of the crescent use of Internet and of the databases and databanks, there were the need of the creation and development of tools that optimize the organization activities, retrieval and interchange of information. XML is one of those developments that have as purpose to facilitate the management, storage and transmission of data through Internet. Before that, it was proposed through a literature revision, to analyze Interchange Format MARC21 and Markup Language XML as tools for the consolidation of the Automated Cooperative Cataloguing, your differences of storage flexibilities, organization, retrieval and interchange of data through Internet. This research made possible the divulgation to the community librarian, through a literature revision, that has been discussed internationally on MARC21 and XML

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OBJECTIVE: Sickle cell anemia and the interaction S/Beta thalassemia differ in hematological values due to microcytosis and hypochromia caused by the thalassemic mutation. The clinical benefit of long-term hydroxyurea treatment is undeniable in sickle cell disease with monitoring of the biological action of the drug being by the complete blood count. The objective of this work is to compare changes in some of the erythrocytic indexes between S/Beta thalassemia and sickle cell anemia patients on long-term hydroxyurea treatment. METHODS: The values of erythrocyte indexes (mean corpuscular volume and mean corpuscular hemoglobin) were compared in a retrospective study of two groups of patients (Sickle cell anemia and S/Beta thalassemia) on hydroxyurea treatment over a mean of six years. RESULTS: The quantitative values of the two parameters differed between the groups. Increases in mean corpuscular volume and reductions in mean corpuscular hemoglobin delay longer in S/Beta thalassemia patients (p-value = 0.018). CONCLUSION: Hematological changes are some of the beneficial effects of hydroxyurea in sickle cell disease as cellular hydration increases and the hemoglobin S concentration is reduced. The complete blood count is the best test to monitor changes, but the interpretation of the results in S/Beta thalassemia should be different.