Environmental lead poisoning among children in Porto Alegre state, Southern Brazil

OBJECTIVE: To estimate the prevalence of lead poisoning in children and to identify associated factors, as well as possible local sources of contamination. METHODS: A cross-sectional prevalence study conducted in 2006 with a random sample of 97 children age zero to five years from a neighborhood in Porto Alegre, Southern Brazil. Blood lead levels were measured and a questionnaire administered to collect information on sociodemographics, recycling and dwelling. A preliminary environmental evaluation was carried out with direct analysis of soil and indirect analysis of air pollution with bioindicators to identify possible sources of contamination. To analyze lead concentrations from the different collection sites, for each type of material studied, ANOVA was performed with a Brown-Forsythe adjustment for heteroscedasticity and with Dunnett's T3 procedure for multiple comparisons of unequal variances. RESULTS: Blood lead levels >= 10.0 mu g/dL was found in 16.5% of children. Recycling of waste at home, low father's education level, and increased age of children were associated with increase blood lead levels. High lead levels were found in soil, and there was little indication of lead air pollution. CONCLUSIONS: A high prevalence of lead poisoning was identified, and the potential sources of contamination in this community appear related to waste recylcing activities. Studies should be conducted with other populations of Brazilian children and evaluate potential sources of local and general contamination, to accurately characterize this issue in Brazil.

Habitação e gestão ambiental em áreas de mananciais: o caso do município de Santo André (SP)

Este artigo tem como objetivo levantar e discutir as ações de gestão ambiental e sua interface com a questão habitacional junto à área administrada pela Subprefeitura de Paranapiacaba e Parque Andreense, Santo André-SP, no biênio 2007-2008. O foco do trabalho é a capacidade política e institucional do município criada para tratar de tais questões. Os métodos usados foram pesquisa documental, bibliográfica e de campo, com entrevista a gestores do município. A pesquisa identificou que o município conta com propostas com grande potencial de contribuição para a melhoria da qualidade ambiental e habitacional na área de mananciais, principalmente por seu caráter de integração entre planejamentos. O estabelecimento de conselhos com participação de várias pastas representa um potencial elemento de integração nas ações desses órgãos, permitindo o compartilhamento de temas pertinentes ao longo do desenvolvimento das agendas de forma contínua. Quanto à recuperação urbana e ambiental dos loteamentos irregulares, é possível afirmar que os parâmetros urbanísticos e a definição do uso e ocupação do solo estão intimamente relacionados à qualidade ambiental e precisam ser construídos em conjunto por profissionais da área de urbanismo e da área ambiental, e discutidos com a comunidade local. O formato de gestão na área de mananciais, foco deste estudo de caso no município de Santo André, representa um significativo passo na construção da integração entre os sistemas de gerenciamento de recursos hídricos e de planejamento urbano/metropolitano.

Participação em políticas públicas para conservação de matas ciliares no Estado de São Paulo

O presente artigo visa a contribuir para os diálogos sobre políticas públicas relacionadas à conservação e restauração de matas ciliares no estado de São Paulo, considerando as possibilidades de participação social em sua formulação e implementação. A pesquisa que gerou as considerações aqui apresentadas baseou-se na análise da implementação e dos resultados do Projeto de Recuperação de Matas Ciliares (PRMC), uma intervenção conduzida pela Secretaria de Estado de Meio Ambiente do Estado de São Paulo (SMA-SP) visando a gerar subsídios para a elaboração de um programa de longo prazo de conservação e restauração de matas ciliares nesse Estado. O método de pesquisa incluiu a análise de documentos oficiais referentes ao projeto de intervenção; entrevistas qualitativas com funcionários dos quadros da SMA-SP e da Secretaria de Agricultura e Abastecimento do Estado de São Paulo - SAA-SP, esta última corresponsável pela implantação do projeto; além de entrevistas semi-estruturadas com proprietários rurais e representantes das organizações não governamentais envolvidas na execução dos projetos-piloto implementados durante o PRMC. A pesquisa mostra que as dificuldades de integração intra e interinstitucional - entre as coordenadorias e departamentos da SMA-SP, e desta com a SAA-SP - bem como a falta de priorização da participação, mobilização social e educação ambiental no PRMC, foram os principais fatores limitantes para o sucesso do Projeto no recorte aqui tratado.

Prevalence and Predictors of Potential Drug-Drug Interactions in the Elderly: A Cross-Sectional Study in the Brazilian Primary Public Health System

Purpose. The primary objective of this study was to investigate the prevalence of clinically important potential drug-drug interactions (DDIs) in elderly patients attending the public primary health care system in Brazil. The secondary objective was to investigate possible predictors of potential DDIs. Methods. A cross-sectional study was carried out in 5 Brazilian cities located in the Ourinhos Micro-region, Sao Paulo State, between November 2010 and April 2011. The selected sample was divided according to the presence (exposed) or absence (unexposed) of one or more potential DDIs (defined as the presence of a minimum 5-day overlap in supply of an interacting drug pair). Data were collected from medical prescriptions and patients' medical records. Potential DDIs (rated major or moderate) were identified using 4 DDI-checker programs. Logistic regression analysis was used to study potential DDI predictors. Results. The prevalence of clinically important potential DDIs found during the study period was 47.4%. Female sex (OR = 2.49 [95% CI 2.29-2.75]), diagnosis of = 3 diseases (OR = 6.43 [95% CI 3.25-12.44]), and diagnosis of hypertension (OR = 1.68 [95% CI 1.23-2.41]) were associated with potential DDIs. The adjusted OR increased from 0.90 [95% CI 0.82-1.03] in patients aged 60 - 64 years to 4.03 [95% CI 3.79 - 4.28] in those aged 75 years or older. Drug therapy regimens involving = 2 prescribers (OR = 1.39 [95% CI 1.17-1.67]), = 3 drugs (OR = 3.21 [95% CI 2.78-3.59]), = 2 ATC codes (OR = 1.19 [95% CI 1.12-1.29]), = 2 drugs acting on cytochrome P450 (OR = 2.24 [95% CI 2.07-2.46]), and ATC codes B (OR = 1.89 [95% CI 1.05-2.08]) and C (OR = 4.01 [95% CI 3.55-4.57]) were associated with potential DDIs. Conclusion. Special care should be taken with the prescription and therapeutic follow-up of patients who present characteristics identified as predictors. Knowledge of potential DDI predictors could aid in developing preventive practices and policies that allow public health services to better manage this situation.

Electroconvulsive Therapy in Brazil After the "Psychiatric Reform" A Public Health Problem-Example From a University Service

Objectives: The Brazilian public health system does not provide electroconvulsive therapy (ECT), which is limited to a few academic services. National mental health policies are against ECT. Our objectives were to analyze critically the public policies toward ECT and present the current situation using statistics from the Institute of Psychiatry of the University of Sao Paulo (IPq-HCFMUSP) and summary data from the other 13 ECT services identified in the country. Methods: Data regarding ECT treatment at the IPq-HCFMUSP were collected from January 2009 to June 2010 (demographical, number of sessions, and diagnoses). All the data were analyzed using SPSS 19, Epic Info 2000, and Excel. Results: During this period, 331 patients were treated at IPq-HCFMUSP: 221 (67%) were from Sao Paulo city, 50 (15.2%) from Sao Paulo's metropolitan area, 39 (11.8%) from Sao Paulo's countryside, and 20 (6.1%) from other states; 7352 ECT treatments were delivered-63.0% (4629) devoted entirely via the public health system (although not funded by the federal government); the main diagnoses were a mood disorder in 86.4% and schizophrenia in 7.3% of the cases. Conclusions: There is an important lack of public assistance for ECT, affecting mainly the poor and severely ill patients. The university services are overcrowded and cannot handle all the referrals. The authors press for changes in the mental health policies.