Samford, Andrew, autographed letter signed to John Winthrop, 1 side (2 pages), undated

Correspondence soliciting Winthrop's advice for treating an illness in Samford's wife, whose symptoms included pain and weakness in her back and legs.

Rood, Sarah, autographed letter signed to John Winthrop, 1 side (2 pages), undated

Correspondence requesting Winthrop's advice for treating a condition Rood describes as a "falling out of [the] wome" (prolapsed uterus) that occurred after her first childbirth and has worsened with the birth of her second child.

Towslande, Richard, autographed letter signed to John Winthrop, 1 side (2 pages), 1652 January 30

Correspondence requesting directions for administering medicine Winthrop had sent for Towslande's wife.

Commission of Noah Cooke, Jr., as chaplain in the Continental Army, signed by John Hancock, 1776 January 1

Commission of Noah Cooke, Jr., as chaplain in the Continental Army, signed by John Hancock, 1 January 1776.