Citotoxicidade do ácido peracético: avaliação metabólica, estrutural e de morte em fibroblastos L929

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeitos do treinamento aeróbio intervalado periodizado sobre os parâmetros antropométricos, bioquímicos e clínicos em portadores de síndrome metabólica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência da temperatura e do termoperíodo sobre a taxa metabólica de repouso em cascavéis, Crotalus durissus (Serpentes: Viperidae)

Snakes are ectothermic animals and, therefore, their physiological functions are strongly affected by temperature. For instance, the resting metabolic rate (RMR) of this animals increase with the rise in body temperature. However, metabolic determinations in ectothermic organisms, including snakes, are generally made by submitting the animals to constant temperature regimes. This experimental procedure, although widely used, accepted and certainly suitable in several cases, submit the animals to a very different situation from that experienced by them in nature. In fact, ectothermics are known by presenting extensive variations in their body temperatures trough the day and/or seasons. If this disagreement between the thermal biology of the animals and the experimental conditions, for instance over the circadian cycle, affects the determinations of metabolic rates of ectotherm animals, remains quite uncertain. Thus, this study aimed to test the effects of different thermal regimes (fluctuating vs constant) in different temperature ranges over the TMR of rattlesnakes (Crotalus durissus). Therefore, the TMR of rattlesnakes was measured by the oxygen consumption rates ( V O2) in the constant temperatures of 15°C, 20°C, 25°C, 30°C and 35°C. For fluctuating regimes, snakes were measured in thermoperiods of 12/12 hours, as follows: 15°C and 25°C; 20°C and 30°C; 25°C and 35°C. Our results show that the RMR of C. durissus rises as the temperature increases, regardless of the thermal regime. The obtained RMR in the constant regimes of 20°C and 25°C was not different from that measured in the correspondent fluctuating regimes (i.e., 15 - 25°C e 20 - 30°C). However, at constant 30°C, the RMR was significantly higher than that obtained in the 30°C fluctuating regime (25 - 35ºC). This indicates that the potential effects in submitting of snakes to different thermal regimes of its thermal biology become more important with...

Programação por metas e análise envoltória de dados na avaliação de unidades de produção global: uma aplicação em uma empresa do segmento químico

Considering the high competitivity in the market, the application of quantitative methods can assist in analyzing the efficiency of production facilities of areas of export and import processes of the chemical industry sector. In this sense, this work aims to apply the model GPDEA-BCC optimization in order to develop an analysis of the production units of this chemical industry. So, were chosen variables relevant to the process and elaborated a final comparison between the results obtained by the optimization tool and performance indexes provided by the company. These results indicated that some production units should be monitored more carefully because some of them had a low efficiency when analyzed with multi criteria

Um Modelo de otimização inteira mista na programação de produção de mangueiras hidráulicas

This work deals with a problem of mixed integer optimization model applied to production planning of a real world factory that aims for hydraulic hose production. To optimize production planning, a mathematic model of MILP Mixed Integer Linear Programming, so that, along with the Analytic Hierarchy process method, would be possible to create a hierarchical structure of the most import criteria for production planning, thus finding through a solving software the optimum hose attribution to its respective machine. The hybrid modeling of Analytic Hierarchy Process along with Linear Programming is the focus of this work. The results show that using this method we could unite factory reality and quantitative analysis and had success on improving performance of production planning efficiency regarding product delivery and optimization of the production flow

Prevalência da síndrome metabólica em moradores adultos do Arquipélago de Fernando de Noronha (PE)-Brasil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação do estresse oxidativo e ingestão dietética de antioxidantes em indivíduos portadores de síndrome metabólica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Impacto de andrógenos sobre a proliferação e atividade de fibroblastos e células epiteliais em cultura celular

Pós-graduação em Odontologia - FOAR