Avaliação do potencial citotóxico, genotóxico e mutagênico da melitina em cultura de células

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Potencial de contribuição e importância socioambiental dos 'catadores autônomos' de Rio Claro (SP) para o programa de coleta seletiva municipal

The Urban Solid Residues are the rests of human activity, popularly known by trash and considered by population like useless, undesirable and disposable. On the other hand, for the waste pickers, solid residues are the beginning of a cycle: they see in the other's people trash the only income, an economic value. Currently, in brazilian cities, one million collectors act, alone or in cooperatives, socially excluded by the work they do. The National Policy of Solid Residues (PNRS), instituted in 2010, established guidelines to the execution of integrated residues management, with should be practiced by city halls and other governmental institutions. This policy has, besides other things, goals of residues reduction and inclusion of waste pickers in the mechanism of selective collect and recycling. However, this and other public policies created for residue management are benefic only for cooperated waste pickers. That could negatively affect most of this class, since 90% are waste pickers working in a precarious way on the country's streets. This study has for objective show that most of waste pickers that work in a precarious way on the brazilian territory has a huge potential for the solid residues recycling chain and how they should be valued for the environmental services they provide, so they can be included with dignity on the society, ensuring economic and social benefits for this workers. The methodology adopted was based on the amount of residue collected by the 44 cooperated members of the Rio Claro‟s waste pickers cooperative to estimate the potential of collect and recycling did by 210 autonomous waste pickers who are active on city streets. It was observed that the cooperative collects the equivalent of 10.2% of all recyclable residues generated by city population. However, with the potential that these autonomous waste pickers have, which together could contribute 465 tonnes of solid residues per month, or 5,570 tons a year...

Potencial gravitacional lunar

We know that the orbit of a lunar satellite, and consequently its orbital lifetime is mainly inuenced by the gravitational field of the Moon, Earth and Sun. In this text we study the Lunar gravitational potential and its influence on the gravitational field. We adapted a program in order to map the Moon gravitational field. To that end it was necessary to develop a program that allows the simulation and mapping the lunar full potential. Our program was based on the program developed by Hélio Kuga, and adapted to our case (Moon). We used the model proposed by Konopliv et al. 2001, we proposed various degree and order expansions of spherical harmonics that served us to compare and validate our program

Estimativa do potencial de acréscimo da oferta de energia no setor sucroalcooleiro paulista a partir de cogeração e gaseificação do bagaço de cana-de-açúcar com utilização de ciclo combinado

This work evaluates the existing potential in the state of Sao Paulo for the generation of electrical energy using the sugar cane bagasse as fuel. As the bagasse is a by-product of the sugarcane and alcohol industry and it is produced in large scale in the country, mainly in the state of Sao Paulo, it is important to develop researches that aim the best utilization of this input. In order to determine its potential, at first, a study was conducted considering the utilization of the cogeneration, which is a common practice in the plants of the sector. However, it was concluded that the cogeneration could provide a higher quantity of energy if more modern technologies and more efficient processes were used. Another study to estimate the potential considered a system of gasification of the sugar cane bagasse integrated with the combined cycle (BIG/GTCC). It was concluded that this technology can provide a considerable increase in the electrical supply. In this work it was also developed an energetic study based on real data from a plant located in the state of Sao Paulo. A thermodynamic analysis was done in the existing equipment of the cogeneration section of the plant. And another analysis was done considering the implementation of the BIG/GTCC technology to the cogeneration system. Comparing the results of both settings, it was concluded that the utilization of the sugar cane bagasse integrated to a combined cycle increased considerably the efficiency in the generation of electricity of the plant, increasing more than six times its production capacity of electrical energy

Potencial do uso do ácido cafeico em formulações cosméticas: atividade antioxidante, atividade despigmentante e citotoxicidade

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Potencial antibacteriano de cogumelos das espécies Lentinus edodes, Agaricus bisporus e Agaricus blazei com enfoque no Helicobacter pylori

A busca por novos agentes antimicrobianos é muito importante, uma vez que as bactérias possuem um alto potencial de recombinação genética, levando a um aumento de cepas resistentes aos fármacos antimicrobianos já existentes. Nesse contexto, os cogumelos podem ser uma alternativa, uma vez que extratos e constituintes químicos destes apresentam atividade frente a diversos isolados patogênicos e utilizados na medicina popular. Dentre as espécies de maior interesse estão o Agaricus blazei (cogumelo do sol), Agaricus bisporus (champignon de Paris) e Lentinus edodes (shitake). O Helicobacter pylori é responsável por doenças gastrointestinais de extrema importância para a saúde pública, como úlceras, gastrites até tumores malignos. O tratamento mais utilizado nos controles deste micro-organismo não é eficaz. Os cogumelos aparecem como alternativa para novas pesquisas neste ramo podendo vir a ser utilizados no desenvolvimento de novo fitoterápico ou mesmo como adjuvante deste tratamento. Existem diversos métodos para determinar a atividade antimicrobiana, entre eles a microdiluição. Esta técnica vem sendo muito utilizada principalmente devido à sua sensibilidade e pequena quantidade de reagentes e amostras, o que possibilita um maior número de réplicas, aumentando a confiabilidade dos resultados. Em continuidade ao estudo do nosso grupo de pesquisa este trabalho objetiva determinar o potencial anti-H. pylori de espécies de cogumelos comestíveis instigados pela possibilidade de encontrar uma alternativa para o tratamento desse micro-organismos dada a importância do mesmo na saúde pública. A atividade antibacteriana dos diferentes extratos de Lentinus edodes, Agaricus bisporus, obtidos por infusão, ultrassom e maceração e de extratos purificados de Agaricus blazei e da substância isolada β-glucana foi determinada pela técnica de microdiluição a fim de obter a concentração inibitória mínima (CIM) frente às...

Oscilador harmônico unidimensional via transformada unilateral de Fourier e mapeamento do potencial de morse unidimensional nos potenciais pseudo-harmônico e de kratzer tridimensionais

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Repensando a metodologia do Índice de Potencial de Consumo (IPC) para estudos sobre consumo nas cidades medias

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Importância da resposta auditiva de estado estável no diagnóstico da surdez em lactentes com risco para a deficiência auditiva: correlações com os achados do potencial evocado auditivo de tronco encefálico

Pós-graduação em Bases Gerais da Cirurgia - FMB