Análise histopatológica de fígado de tilápias (Oreochromis Niloticus) expostas ao herbicida 2,4-D comercial

The action of man has led, over the years, major impacts on the environment, especially in aquatic ecosystems, leading to an impairment of water quality, considered one of the essential factors for the maintenance of vital functions and consequently the life of the planet. Among the activities considered a risk for the environment are linked to pollution from many sources and even entire watersheds, whether by industrial waste, sewage, or for substances used in agriculture, such as pesticides, herbicides and fertilizers. The (2,4-D) 2,4- dichlorophenoxyacetic acid is used worldwide, and the fact that its genotoxicity is proven by several studies and by its long persistence in soil, which enables the leaching and percolation of compounds affecting water bodies, toxicity studies are relevant and justifiable. Thus, this study aimed to evaluate the toxicity of 2,4-D by examining the liver of the fish Oreochromis niloticus exposed to different dilutions. Portions of liver were collected and fixed for histological and histochemical techniques to detect total proteins, polysaccharides and lipids. lipids. Treatment with 2,4-D herbicide apparently did not alter the lipid profiles, the accumulation of polysaccharides, and the presence of total proteins. The 2.5 and 5.0% were lethal to fish. These mortalities are probably of high toxic and cytotoxic potential of 2,4-D herbicide results. Several histopathological changes were found, such as: loss of cytoplasmic integrity, loss of cell limit, nuclear deformation, vacuolated cytoplasm, tissue disorganization and hydropic degeneration. Statistically significant changes were: hydropic degeneration and vacuolated cytoplasm. It is concluded, therefore, that the qualitative morphological analysis is an important method for observing changes in liver toxicology studies. As the O. niloticus species is an efficient biological indicator of water pollution by 2,4-D

Políticas e desenvolvimento do estado de Mato Grosso após abertura comercial: análise da visão de dois empresários atuantes no setor

After realizing two interviews, with distinct managers/businessmen working in the cotton industry, the objective is to put in evidence the political, economical and social factors that contributed to the formation and configuration of the Mato Grosso state, after the trade liberalization that occurred in the early 90's, it's effects and consequences in the eyes of the interviewed. The study of public policies is primordial to the discovery of the configuration of determined place, evaluating advances and possible errors in the social, economical and environmental areas. Through the analysis of the interviews it has been found that the urban centers have been developing with a direct link to the industrial activities related to agriculture and that the labor work force have also been attracted because of these changes, and as a consequence this labor force is now becoming more specialized to be able to accompany the jobs requirements in the industry. Analyzing the interviews, it is possible to highlight some information about the development of Mato Grosso, among those the following factors and public policies. The creation and expansion of the cities in the state are possible through public and private investment in infrastructure the socioeconomic development of the state is linked with the advances made in the private sector that grows because of advances made in crops technology in contrast to the occupation of the cerrado, in relation to the cotton crops. The problems that Mato Grosso is facing are mainly linked to the region infrastructure, that can count on investment plans to transportation and production flow that dates before the globalization era. The pattern that is seen today with top of the line agricultural production, big monoculture with high productivity and the arrival of multinational giants, was implanted because of two important events: the trade liberalization in the 1990's and the cambial depreciation in the 1999's...

Lógicas espaciais das empresas franqueadas do ramo comercial de confecções e calçados: cidades médias e consumo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)