2 resultados para MULTIVALENT DENDRONS

em Repositorio Institucional de la Universidad de Málaga


Relevância:

20.00% 20.00%

Publicador:

Resumo:

Our proposal aims to display the analysis techniques, methodologies as well as the most relevant results expected within the Exhibitium project framework (http://www.exhibitium.com). Awarded by the BBVA Foundation, the Exhibitium project is being developed by an international consortium of several research groups . Its main purpose is to build a comprehensive and structured data repository about temporary art exhibitions, captured from the web, to make them useful and reusable in various domains through open and interoperable data systems.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

A new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide Dendrimers, or BAPAD).[1] The introduction of a cystamine core allows the incorporation of this dendrons into a 1,8-naphthalimide fluorofore functionalized with a maleimide group. The fluorescence properties of this DeAn has been studied and compared with the properties of an equivalent dendron possessing amino-terminal groups. This DeAn has been used as a synthetic antigen in a biomedical assay that tests the amoxicillin sensitivity of dendritic cells (DC) from tolerant and allergic patients.