Abad y señor de Rute. Don Juan de Córdoba y la repoblación de la banda morisca cordobesa

Study on the foundation of the new village of Rute close to the former border with the Muslim kingdom of Granada and the repopulation project and economic revitalization in the Sixteenth century by the dean don Juan Fernández de Córdoba, abbot and lord of Rute.

Câmara Municipal de Loures: uma experiência em arquitetura paisagista no sector público

O presente relatório de estágio reflete o trabalho realizado e a experiência adquirida ao longo de seis meses na Câmara Municipal de Loures. Os trabalhos desenvolvidos correspondem, sobretudo, ao que era pretendido por parte da Câmara Municipal tendo sido aplicados, em parte, os conhecimentos adquiridos ao longo da licenciatura e do mestrado em Arquitetura Paisagista na Universidade de Évora. Este relatório incide sobre a regulamentação do mobiliário urbano em todo o Município de Loures, na caracterização e proposta de intervenção para alguns espaços abertos pertencentes ao concelho e na importância da Arquitetura Paisagista no sector público; ABSTRACT: City Council of Loures: An Experience in Landscape Architecture in the Public Sector This internship report reflects the work done and experience gained over six months at the City Council of Loures. The work developed are primarily to what was intended by the City Council having been applied in part the knowledge acquired throughout the undergraduate and master's degree in Landscape Architecture at the University of Évora. This report focuses on the regulation of street furniture throughout the Loures Municipality, characterization and proposal of intervention for some open spaces belonging to the municipality and the importance of Landscape Architecture in the public sector.

Arquitetura paisagista na Câmara Municipal de Alvito

O presente relatório de estágio ambiciona dar a conhecer todos os trabalhos realizados ao longo do estágio no Gabinete Técnico da Unidade Municipal de Obras e Serviços Urbanos (UMOSU) na Câmara Municipal de Alvito. No decorrer do estágio desenvolveram-se vários trabalhos a nível da Arquitetura Paisagista sendo estes solicitados pela Câmara Municipal. Tendo como base todos os conhecimentos académicos adquiridos ao longo da licenciatura e mestrado em Arquitetura Paisagista ambos doutrinados na Universidade de Évora. Em suma o presente relatório incide sobre o estudo, caracterização e avaliação da paisagem do concelho de Alvito, bem como a análise e proposta de intervenção sobre diversos espaços abertos das freguesias de Alvito. Pretende ainda dar a conhecer à Câmara Municipal as funções de um Arquiteto Paisagista; ABSTRACT: LANDSCAPE ARCHITECTURE IN THE MUNICIPAL COUNCIL OF ALVITO The Present internship Report aims to raise awareness of all the Work Accomplished Along Stage not Technical Office of the Municipal Unit of Works and Urban Services ( UMOSU ) in the Municipal council of Alvito. During intership developed various works at the level of Landscape Architecture being these requested for the City Council. Having bases in how knowledge all academic bought along the undergraduate and master's degree in Landscape Architecture, both indoctrinated in University of Évora. In short the present report covers the study characterization and evaluation of the county of Alvito landscape , as well as the analysis and proposal of on intervention Several Open Spaces of the parishes of Alvito . Also responsible to inform the City Council the functions of a Landscape Architect.

Corredores verdes em Ferreira do Alentejo - a paisagem como infraestrutura

O relatório apresenta o trabalho desenvolvido durante o estágio na Câmara Municipal de Ferreira do Alentejo, objetivado pela obtenção do grau de mestre em Arquitetura Paisagista. Este trabalho pretende valorizar os princípios adquiridos ao longo do percurso académico em licenciatura e mestrado de Arquitetura Paisagista, na ilustre Universidade de Évora, e dar resposta ao objetivo proposto pela entidade acolhedora no presente estágio – a proposta de um percurso potenciador da Paisagem no espaço urbano de Ferreira do Alentejo; ABSTRACT: This report presents the work carried out during the internship at the municipality of Ferreira do Alentejo, which was objectified for obtainment of Master degree in Landscape Architecture. This work aims to enrich the principles acquired during the academic path with the graduation and master degree at the Évora University and to respond to the host institution objective for this internship - the proposal for a landscape enhancer pathway in urban areas of Ferreira do Alentejo.

Programa Escola Segura: contributo para a avaliação dos impactos no concelho de Portalegre

A presente comunicação decorre do desenvolvimento de uma dissertação de mestrado em Administração Escolar, realizada na Universidade de Évora. A investigação em causa incide sobre o tema Programa “Escola Segura” (PES), mais especificamente, sobre a avaliação/caraterização dos impactos do Programa “Escola Segura”, no concelho de Portalegre. Considerou-se relevante a opção da temática, na medida em que, e como sublinha SILVA (2000:44), “a promoção da segurança nas escolas constitui uma responsabilidade de todos. Um ambiente seguro é um requisito básico de funcionamento da comunidade escolar e representa um direito elementar de cada aluno, funcionário e professor.” Educação e segurança são dois aspetos fulcrais da nossa sociedade, que se quer cada vez mais civilizada e evoluída. Assim sendo, este trabalho pretendeu apresentar os resultados do referido estudo, de acordo com o cruzamento de informação recolhida (devidamente analisada e interpretada) de três grupos distintos: alunos, professores e agentes do Programa “Escola Segura”.

Projeto de arquitetura paisagista: Clichy-Batignolles Paris, a resposta a ambições políticas e aos novos desafios urbanos

A cidade resulta de fatores sociais, das políticas urbanas, das dinâmicas económicas e dos valores ambientais, no espaço e no tempo. Compreender a complexidade do seu funcionamento permite ao arquiteto paisagista interagir com ela. O projeto de Clichy-Batignolles, objeto do presente estudo, surge como resposta às problemáticas da cidade, enquanto metrópole de dimensão mundial, de políticas urbanas associadas à competitividade e à atratividade de pessoas e atividades económicas. O projeto integra o parque Martin Luther King senda a referência de desenvolvimento urbano sustentável e ecológico de Paris. A visão metabólica, que o projeto integra, concilia habitação, mobilidade, ecologia, sustentabilidade e experiência de Natureza, que a extensão da aglomeração urbana transformou em necessidade básica. A cidade ecológica impõe-se às politicas urbanas. É neste contexto de crise ambiental, económica e social que a arquitetura paisagista se posiciona no centro dos grandes desafios contemporâneos da evolução das cidades; Abstract: Landscape Architecture Project: Clichy-Batignolles Paris, the answer to policies ambitions and urban new challenges The city is a result social factors, urban policies, economical dynamics and environmental values, in space and time. Understanding the complexity of its mechanism allows the landscape architect to interact with it. The Clichy-Batignolles urban project, the subject of the present study, is a response to the problematic issues of the metropolitan worldwide city, in which competitiveness and attractiveness urban policies are created to attract people and economical activities. The project incorporates the Martin Luther King park and is the reference of ecological and sustainable development in Paris. The metabolic vision of the project conciliates habitation, mobility, ecology, sustainability and Nature experience, which the urban concentration length as transformed in basic living needs. The ecological city is imposed to the megacities urban policies. In this environmental, economic and social crisis context, landscape architecture occupies a center position in the contemporary challenges of cities evolution.

Integração e recuperação paisagística em pedreiras

Esta dissertação, elaborada no âmbito da obtenção do grau de mestre em Arquitetura Paisagista, tem como tema a “Integração e Recuperação Paisagística em Pedreiras”, a qual foi desenvolvida com base no trabalho de investigação desenvolvido, enquanto colaborador no Centro Tecnológico da Pedra Natural de Portugal (CEVALOR) localizado em Borba, desde o ano 2000, até à atualidade. A recuperação de pedreiras pode ser caracterizada, como um processo de intervenção local, inserido no âmbito da gestão visual, da conservação e de valorização da paisagem. Para realizar o processo de recuperação, não só é necessário o correto enquadramento legal, como entender o contexto paisagístico, que permite avaliar os impactes visuais potenciais e propor medidas de mitigação adequadas. O conteúdo metodológico desta dissertação apresenta a análise, interpretação e caracterização estrutural da paisagem assim como da avaliação do impacte visual, assim como as opções de recuperação com vista à sua integração das pedreiras na paisagem; Abstract: Integration and landscape reclamation in quarries This dissertation concerning the theme “landscape integration and rehabilitation of quarries” aims to obtain the master degree in landscape architecture, as the result of my research as a collaborator at CEVALOR since the year of 2000. The integration and rehabilitation of quarries can be described has a process of local intervention within the fields of visual management, conservation and amelioration of the landscape. In order to accomplish the rehabilitation process, not only is necessary to consider all legal obligations but understand the landscape context, through the analysis of the visual quality and the assessment of the visual impacts in order to propose the most adequate mitigation measures. This dissertation presents a methodological approach that describes the process of landscape analysis, landscape visual impact assessment and the feasible rehabilitation options regarding the visual integration of quarries in the landscape.

Study of the allergenic profile of pollen from Platanus hybrida in the city of Evora, Portugal

Background and Aim: Although grasses and olive are the most relevant allergenic species in the Alentejo region, aggravation of allergic symptoms in the early spring, unrelated with those species pollen seasons, has been reported, particularly in urban environment. Plane trees, hence pollen, are highly abundant in the city of Évora, nonetheless allergen pollen profile has not yet been evaluated. The aim of this work was to characterize the allergen profile of pollen from Platanus hybrida, one of the most representative species in Evora showing pollination prior to the main pollen season in Alentejo. Methods: Pollen from Platanus hybrida and Dactylis glomerata was extracted with ammonium bicarbonate buffer, lyophilized and stored at -80ºC until analysis. Protein content was determined by the Bradford method. SDS-PAGE followed by western blot, using allergic patient sera (obtained from the Hospital do Espírito Santo de Évora – HESE), were performed to evaluate the allergen profile of the pollen. Sensitization and cross-reactivity was assessed by solid phase immunoblot. Results: Half of the patient exhibited sensitization to pollen extracts of P. Hybrida. Western blot have shown several immunoreactive bands in the Mr 10-90 kDa range. Immunoreactive bands were also observed in the protein profile according to the pI in the pI range 4.0-6.1. Cross-reactivity of P. hybrida with D. glomerata was found. Although several bands are common to D. glomerata, a band with ~50kDa was observed in P. hybrida but not in D. glometata. Conclusion: These results evidenced allergens found in P. hybrida pollen. Moreover, cross–reactivity between P. hybrida and highly allergenic species such as D. glomerata was found which probably contributes for aggravation of pollinosis in the early spring. Acknowledgments: This work was supported by FEDER through the “Programa Operacional Fatores de Competitividade – COMPETE” (Strategic projects of ICAAM and ICT 2013-2015).

Allergenic profile of Quercus rotundifolia pollen in Alentejo, Portugal

Background and Aim: Grasses and olive are the most relevant allergenic species in the Alentejo region. However, aggravation of allergic symptoms has been reported in the early spring, before grass and olive pollen seasons. Quercus pollen is the most abundant pollen type in the early spring in Alentejo, nonetheless its allergen profile has not yet been evaluated. The aim of this work was to characterize the allergen profile of pollen from Quercus rotundifolia among the most representative species showing pollination in April, prior to the main pollen season in Alentejo. Methods: Pollen from Quercus rotundifolia, Olea europaea and Dactylis glomerata was extracted with ammonium bicarbonate buffer, lyophilized and stored at -80ºC until analysis. Extract from Quercus ilex pollen was kindly offered by Bial. Protein content was determined by the Bradford method. SDS-PAGE followed by western blot, using allergic patient sera (obtained from the Hospital do Espírito Santo de Évora – HESE), were performed to evaluate the allergen profile of the pollen. Sensitization and cross-reactivity was assessed by solid phase immunoblot. Results: Most of the patient evidenced sensitization to pollen extracts of Q. rotundifolia. Protein profile of Q. rotundifolia has shown several bands in the Mr 10-90 kDa, mostly overlapping with Q. ilex. Western blot have shown several immunoreactive bands. Immunoreactive bands were also observed in the protein profile according to the pI in the range 4.0-6.1. Cross-reactivity between Q. rotundifolia with O. europaea and D. glomerata was found. Conclusion: These results evidenced allergens found in Q. rotundifolia pollen. It also shows that protein profile of Q. rotundifolia and Q. ilex are mostly alike suggesting that similarities in allergen profile are expected. Moreover, cross–reactivity between Q. rotundifolia and highly allergenic species such as O. europaea and D. glomerata was found which probably contributes to the aggravation of pollinosis in the early spring. Acknowledgments: This work was supported by FEDER through the “Programa Operacional Fatores de Competitividade – COMPETE” (Strategic projects of ICAAM and ICT 2013-2015). We also aknowledge Bial-Aristegui for supplying pollen and extract samples of Q. ilex.

Anti-proliferative effects of novel hydroxyamides and triazoles

Chemotherapy is a major cancer treatment option. The synthesis of new compounds with anti-proliferative properties and specificity is a current challenge in drug-discovery today. Our goal was to develop compounds, either hydroxyamides derived from D-glucuronic acid or triazole-cinchone hybrids, and to evaluate their anti-proliferative properties. Anti-proliferative activity of the newly synthesized compounds was examined against human breast adenocarcinoma (MCF-7) and human colon carcinoma (MDST8) cell-lines. Cell growth and viability was analysed by the Cell-Counting Kit-8 method. The 5-fluoroacil was used as a positive control. The compounds were studied between 10-9-10-5M. Fifteen compounds from the hydroxyamide family and two triazole compounds were investigated. Most of the compounds from the hydroxyamide family revealed mild (~20%) to moderate (50%) anti-proliferative effects in both cell-lines, with the exception of Hydroxyamide B1 which did not affect MDST8 proliferation, and hydroxyamide B3 where proliferation of MDST8 was inhibited by 90%. Triazoles (A and B) evoked a strong (~100%) anti-proliferative effect of MDST8 cell-lines. Proliferation of MCF-7 was selectively and effectively (~98%) inhibited by triazole B while triazole A had a mild effect. In conclusion, when compared to hydroxyamides, triazoles evoked a stronger anti-proliferative effect and might be promising anti-tumoral drugs.