A randomized controlled trial on the effects of combined aerobic-resistance exercise on muscle strength and fatigue, glycemic control and health-related quality of life of type 2 diabetes patients

Aim: to evaluate the effects of a 12-weeks combined aerobic-resistance exercise therapy on fatigue and isokinetic muscle strength, glycemic control and health-related quality of life (HRQoL) in moderately affected type 2 diabetes (T2DM) patients. Methods: a randomized controlled trial design was employed. Forty-three T2DM patients were assigned to an exercise group (n = 22), performing 3 weekly sessions of 60 minutes of combined aerobic-resistance exercise for 12-weeks; or a no exercise control group (n = 21). Both groups were evaluated at a baseline and after 12-weeks of exercise therapy for: 1) muscle strength and fatigue by isokinetic dynamometry; 2) plasma glycated hemoglobin A1C (HbA1C); and 3) HRQoL utilizing the SF-36 questionnaire. Results: the exercise therapy led to improvements in muscle fatigue in knee extensors (-55%) and increased muscle strength in knee flexors and extensors (+15 to +30%), while HbA1C decreased (-18%). In addition, the exercising patients showed sizeable improvements in HRQoL: physical function (+53%), vitality (+21%) and mental health (+40%). Conclusion: 12-weeks of combined aerobic-resistance exercise was highly effective to improve muscle strength and fatigue, glycemic control and several aspects of HRQoL in T2DM patients. These data encourage the use of aerobic and resistance exercise in the good clinical care of T2DM.

Jorge Afonso: uma interrogação essencial na pintura primitiva portuguesa

O pintor Jorge Afonso (c. 1480-1540) ocupou cargos da maior importância e foi mestre de alguns dos mais importantes artistas da primeira metade do século XVI. Por laços familiares, por ligações profissionais, ou como representante régio no fornecimento e controle de empreitadas, esteve no centro das grandes obras artísticas do seu tempo. Fez uma carreira como oficial de armaria dentro da reestruturação manuelina, o que o tornou, também do ponto de vista simbólico, uma figura importante da corte do Venturoso. A Jorge Afonso são atribuídas as grandes tábuas da Charola do Convento de Cristo de Tomar, oito pinturas do mosteiro da Madre de Deus e o retábulo do Convento de Jesus de Setúbal. A dissertação reanalisa os dados biográficos do pintor, estuda as pinturas incluindo o seu desenho subjacente, e reelabora a compreensão da pintura portuguesa do tempo, vista sob a influência desta figura tutelar; ABSTRACT: Jorge Afonso. An essential quest on Portuguese primitive painting. Painter Jorge Afonso (1480-1540), held positions of major importance and was master of some of the most remarkable artists of the first half of the 16th century. By family links, by professional connections or as Royal representative for the supply and control of works, he was at the very center of the great artistic works of his time. He built a career as Herald what made him an important figure in King D. Manuel’s court . To Jorge Afonso are attributed the large paintings of the ‘Christ’s Convent’ Ambulatory in Tomar, eight paintings from the ‘Madre de Deus’ monastery and the ‘Covent of Jesus’ altarpiece in Setubal. This dissertation reanalysis the painter biographical data, studies the paintings including its underdrawing and reconstructs the understanding of Portuguese painting of that time, perceived under the influence of this tutelary figure.

“Moniz, Jorge Botelho (1898-1961)”

Jorge Botelho Moniz