Produtos têxteis inteligentes incorporando filamentos compósitos com nanotubos de carbono

Programa Doutoral em Engenharia Têxtil.

Inkjet printing technology for flexible pressure sensors

Tese de Doutoramento Ciência e Engenharia de Polímeros e Compósitos.

Eco-friendly luminescent hybrid materials based on EuIII and LiI co-doped chitosan

Biopolymer-based materials have been of particular interest as alternatives do synthetic polymers due to their low toxicity, biodegradability and biocompatibility. Among them, chitosan is one of the most studied ones and has recently been investigated for the application as solid state polymer electrolytes. Furthermore, it can serve as a host for luminescent species such as rare earth ions, giving rise to materials with increased functionality, of particular interest for electrochemical devices. In this study, we investigate chitosan based luminescent materials doped wit Eu3+ and Li+ triflate salts from the structural, photophysical and conductivity points of view. Because the host presents a broad emission band in the blue to green, while Eu3+ emits in the red, fine tuning of emission colour and/or generation of white light is possible by optimizing composition and excitation scheme. Europium lifetimes (5D0) are in the range 270 – 350 µs and quantum yields are as high as 2%. Although Li+ does not interfere with the luminescent properties, it grants ion-conducting properties to the material suggesting that a combination of both properties could be further explored in multifunctional device.

Gellan gum-Ionic liquid membranes for electrochromic device application

Biopolymer-based materials have been of particular interest and they are alternatives to synthetic polymers based on the decreasing oil resources. The polymer electrolytes were doped with choline-based IL N,N,Ntrimethyl- N-(2-hydroxyethyl)ammonium bis(trifluoromethylsulfonyl)imide ([N1 1 1 2(OH)][NTf2]), or Er (CF3SO3)3 or both. The polymer electrolytes were employed in the production of glass/ITO/WO3/electrolyte/ CeO2–TiO2/ITO/glass electrochromic devices (ECDs). The lowest onset temperature for the degradation of all the SPEs is at ~130 °C for the Gellan Er (CF3SO3)3 (10:1) this temperature range of stability is wide enough for a material to be applied as an electrolyte/separator component in electrochemical devices. The three ECDs displayed fast switching speed (ca. 15 s). Gellan [N1 1 1 2(OH)][NTf2] Er (CF3SO3)3 (5:1:10) exhibited an electrochromic contrast of 4.2% in the visible region, the coloration efficiency attained at 555 nm was 3.5 and 0.90 cm-2 C-1 in the “colored” and “bleached” states, respectively, and the open circuit memorywas 48 h. Preliminary tests performed with a prototype electrochromic device (ECD) incorporating WO3 as cathodic electrochromic layer, are extremely encouraging.

Highly functional and biodegradable nanofibrous scaffolds combined with stem cells for bone and cartilage tissue engineering

Among the various possible embodiements of Advanced Therapies and in particular of Tissue Engineering the use of temporary scaffolds to regenerate tissue defects is one of the key issues. The scaffolds should be specifically designed to create environments that promote tissue development and not merely to support the maintenance of communities of cells. To achieve that goal, highly functional scaffolds may combine specific morphologies and surface chemistry with the local release of bioactive agents. Many biomaterials have been proposed to produce scaffolds aiming the regeneration of a wealth of human tissues. We have a particular interest in developing systems based in nanofibrous biodegradable polymers1,2. Those demanding applications require a combination of mechanical properties, processability, cell-friendly surfaces and tunable biodegradability that need to be tailored for the specific application envisioned. Those biomaterials are usually processed by different routes into devices with wide range of morphologies such as biodegradable fibers and meshes, films or particles and adaptable to different biomedical applications. In our approach, we combine the temporary scaffolds populated with therapeutically relevant communities of cells to generate a hybrid implant. For that we have explored different sources of adult and also embryonic stem cells. We are exploring the use of adult MSCs3, namely obtained from the bone marrow for the development autologous-based therapies. We also develop strategies based in extra-embryonic tissues, such as amniotic fluid (AF) and the perivascular region of the umbilical cord4 (Whartonâ s Jelly, WJ). Those tissues offer many advantages over both embryonic and other adult stem cell sourcess. These tissues are frequently discarded at parturition and its extracorporeal nature facilitates tissue donation by the patients. The comparatively large volume of tissue and ease of physical manipulation facilitates the isolation of larger numbers of stem cells. The fetal stem cells appear to have more pronounced immunomodulatory properties than adult MSCs. This allogeneic escape mechanism may be of therapeutic value, because the transplantation of readily available allogeneic human MSCs would be preferable as opposed to the required expansion stage (involving both time and logistic effort) of autologous cells. Topics to be covered: This talk will review our latest developments of nanostructured-based biomaterials and scaffolds in combination with stem cells for bone and cartilage tissue engineering.

Desenvolvimento de um protótipo didático de uma máquina de corte de pedra por fio diamantado

Dissertação de mestrado integrado em Engenharia Mecânica

José Anastácio da Cunha e o projeto MAT² : no trilho de uma história extraordinária

A ideia de que as Matemáticas de Portugal (e de Espanha) atravessaram, depois de um período áureo nos Descobrimentos, um longo deserto onde não foi possível florescerem Mestres, nem escolas, nem cultura científica, nem investigação de relevo foi, durante muito tempo, reiteradamente veiculada, inclusivé através de alguns dos nossos mais referenciados historiadores da Matemática, como é o caso de Gomes Teixeira ou de Rey Pastor. Mas a verdade é que o estudo da História das Matemáticas em Portugal tem, na última década, vivido um interesse crescente onde sobressaem, em particular, uma leitura menos enviesada sobre, por exemplo, o papel educativo dos Jesuítas ou a publicação das obras completas de Pedro Nunes. Está-se assim a contribuir para uma compreensão mais completa da História geral de Portugal, de que a História da Ciência e da Cultura faz parte. José Anastácio da Cunha (1744-1787) foi figura de proa no século XVIII português. Sabíamo-lo matemático que, sem nunca ter saído de Portugal, havia sido capaz de antecipar, em mais de 50 anos, os esforços de matemáticos franceses e alemães para fundar a Matemática com rigor. Sabíamo-lo também autor de uma vasta e diversificada obra de inegável importância matemática mas, igualmente, autor de textos poéticos. Agora, com o projecto que denominámos de MAT2, centramo-nos em José Anastácio da Cunha e pretendemos, se possível, ir ainda mais além. Partimos de uma descoberta, árdua mas com final feliz, em um Arquivo de família: o da Casa de Mateus. Sentimo-nos, com esta “sorte”, privilegiados e gratos por nos ter sido gentilmente concedido o acesso a um vasto conjunto de documentos únicos (diários de viagens, notas de aulas e correspondência) que incluem memórias autógrafas e inéditas de Anastácio da Cunha. Organizámo-nos, cientes do trabalho árduo que temos pela frente, multi e interdisciplinarmente englobando a Matemática (nas suas múltiplas especializações) e a História (incluindo a da Matemática) mas também contando com a Física, a Informática, os estudos militares ou a Arquivística e as Humanidades; reunimos académicos, mais e menos veteranos, com investigadores jovens e juntámos valências nacionais e estrangeiras. No presente artigo daremos conta do percurso trilhado, até agora, pelo projecto MAT2.

Unfuzzying fuzzy parsing

Dissertação de Mestrado em Engenharia Informática

Interacting and making personalized recommendations of places of interest to tourists

Advances in Intelligent Systems and Computing, 353

A liberdade de circulação de pessoas no contexto da cidadania da União Europeia: acesso aos benefícios sociais

Dissertação de mestrado em Direitos Humanos

O Esclavagismo dos Tempos Modernos e a Tutela Jurídica das suas Vítimas: os meios jurídicos ao serviço da recuperação psicológica das vítimas de tráfico de seres humanos

Dissertação de mestrado em Direitos Humanos

Para um (novo) modelo de intervenção penal na União Europeia: uma reflexão a partir do princípio de legalidade como limite material de atuação da Procuradoria Europeia

Tese de Doutoramento em Ciências Jurídicas (área de especialização em Ciências Jurídicas - Públicas)

Mechanism of extracellular silver nanoparticles synthesis by Stereum hirsutum and Fusarium oxysporum

The increasing interest for greener and biological methods of synthesis has led to the development of non-toxic and comparatively more bioactive nanoparticles. Unlike physical and chemical methods of nanoparticle synthesis, microbial synthesis in general and mycosynthesis in particular is cost-effective and environment-friendly. However, different aspects, such as the rate of synthesis, monodispersity and downstream processing, need to be improved. Many fungal-based mechanisms have been proposed for the formation of silver nanoparticles (AgNPs), mainly those involving the presence of nitrate reductase, which has been detected in filtered fungus cell used for AgNPs production. There is a general acceptance that nitrate reductase is the main responsible for the reduction of Ag ions for the formation of AgNPs. However, this generally accepted mechanism for fungal AgNPs production is not totally understood. In order to elucidate the molecules participating in the mechanistic formation of metal nanoparticles, the current study is focused on the enzymes and other organic compounds involved in the biosynthesis of AgNPs. The use of each free fungal mycelium of both Stereum hirsutum and Fusarium oxysporum will be assessed. In order to identify defective mutants on the nitrate reductase structural gene niaD, fungal cultures of S.hirsutum and F.oxysporum will be selected by chlorate resistance. In addition, in order to verify if each compound identified as key-molecule influenced on the production of nanoparticles, an in vitro assay using different nitrogen sources will be developed. Lately, fungal extracellular enzymes will be measured and an in vitro assay will be done. Finally, The nanoparticle formation and its characterization will be evaluated by UV-visible spectroscopy, electron microscopy (TEM), X-ray diffraction analysis (XRD), Fourier transforms infrared spectroscopy (FTIR), and LC-MS/MS.

Instrumentos de políticas públicas do turismo: uma análise empírica dos municípios portugueses

Tese de Doutoramento em Ciências da Administração

Da modelação matemática à simulação computacional: a experimentação matemática no ensino

Tese de Doutoramento em Ciências (área de especialização em Matemática).