Confrontos. A vontade de retrato em Mónica Ortuzar

Desde 2007 que Mónica Ortuzar se toma a si mesma como tema da sua obra plástica: primeiro no desenho, depois na aguarela e na pintura a óleo, em séries de imagens que somam atualmente cerca de quatro centenas de autorrepresentações. Sempre em pequenos ou médios formatos e partindo do seu reflexo no espelho. Sempre em função de um desenho inicial que serve de encaixe às formas das cabeças e dos rostos. Ao mesmo tempo que demonstra uma atenção permanente ao fora de si, num voluntário exercitar de confrontos em que o mundo e os outros servem de primeiro reflexo: Ortuzar constrói cada um dos seus autorretratos como um jogo de referências justapostas e de recíprocos espelhamentos com os que a cruzam, anonimamente, nas estações, nas zonas comerciais das grandes cidades, no caminho para o atelier ou no próprio espaço das suas exposições, situando assim a representação retratística numa zona ambígua entre a esfera pública e a privada. Nas suas imagens, inscreve-se uma relação forte entre a pintura e o(s) sujeito(s), uma relação em que a presença do sujeito-artista se oferece continuamente em estado de diálogo e em que a pintura devém, nesse passo, crítica da própria subjetividade e dos seus meios em pintura.

Bone turnover markers for early detection of fracture healing disturbances: A review of the scientific literature

Imaging techniques are the standard method for assessment of fracture healing processes. However, these methods are perhaps not entirely reliable for early detection of complications, the most frequent of these being delayed union and non-union. A prompt diagnosis of such disorders could prevent prolonged patient distress and disability. Efforts should be directed towards the development of new technologies for improving accuracy in diagnosing complications following bone fractures. The variation in the levels of bone turnover markers (BTMs) have been assessed with regard to there ability to predict impaired fracture healing at an early stage, nevertheless the conclusions of some studies are not consensual. In this article the authors have revised the potential of BTMs as early predictors of prognosis in adult patients presenting traumatic bone fractures but who did not suffer from osteopenia or postmenopausal osteoporosis. The available information from the different studies performed in this field was systematized in order to highlight the most promising BTMs for the assessment of fracture healing outcome.

Fatores de sucesso e dificuldades das spin-offs empresariais: o caso das agências de mediação de seguros

Dissertação de mestrado em Marketing e Estratégia

Exploring the use of HPFRC and GFRP grids for the production of manhole covers

Corrosion of the steel reinforced concrete elements is one of the common pathologies that limits the long-term performance of urban infrastructures. This problem causes the loss of structural serviceability by decreasing the concrete-steel bond strength and reducing the cross section of the reinforcements. The present study introduces a new system for developing free-corrosion resistance prefabricated manhole covers for applications in the aggressive environments, i.e. wastewater collector systems, sewer systems, stormwater systems, etc. Fibre reinforced cement composites were applied in this system in order to suppress the corrodible steel mesh and maintain the structural ductility as well. Application of fibre reinforced polymer (FRP) system is adopted as the additional solution for increasing the load carrying capacity of these elements without concerns about corrosion. The effectiveness of the applied strategy in developing the manhole covers in terms of load carrying capacity and failure mode is evaluated in this research. Furthermore, this paper discusses a FEM-based simulation, aiming to address the possibility of calibrating the constitutive model parameters related to fracture modes I and II.

Lightweight adjustable partition system: evaluation of resistance to horizontal loads and functional failure from impacts

This paper presents and discusses the results of the serviciability and use condition tests carried on an innovative solution for partitions, designated AdjustMembrane developed within a research project. The proposed system is a modular non-loadbearing wall, tensioned between the pavements and ceiling slabs, which are used as anchoring elements. It allows several advantages, related with the weight reduction to achieve a good sustainable performance, such as the reduction of construction costs, energy, and materials, and it is easy to recycle and to reuse, allowing self-construction. Apart from a general presentation of the partition technology, this paper presents and discusses the results of experimental tests carried out. From the results obtained, it is possible to conclude that the solution fulfils the requirements for this typology of wall in terms of resistance to horizontal loads induced by soft and hard body impacts.

Foreword [Occupational Safety and Hygiene III]

[Excerpt] This book is the third edition of this series of publications that are entitled “Occupational Safety and Hygiene”. The main contributions for this book were, once again, the works previously submitted and approved to be presented at the annual Symposium of the Portuguese Society of Occupational Safety and Hygiene (SPOSHO), which is celebrating its 11th edition in 2015. The SHO2015—International Symposium on Occupational Safety and Hygiene, similarly to the past seven years, was held in the School of Engineering at University of Minho in Guimarães, Portugal.

Occupational Safety and Hygiene SHO2015 - Proceedings book

Occupational Safety and Hygiene SHO2015 - Proceedings book

Estudo das propriedades físicas fundamentais de filmes finos intermetálicos do tipo Ti-Me (Me = Al, Au) na funcionalização de elétrodos - sensores para dispositivos biomédicos

Dissertação de mestrado integrado em Engenharia de Materiais

Interação multimodal de dispositivos robóticos em ambiente simulado

Dissertação de mestrado integrado em Engenharia e Gestão de Sistemas de Informação

Monocarboxylate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells

Cancer cells rely mostly on glycolysis to meet their energetic demands, producing large amounts of lactate that are extruded to the tumour microenvironment by monocarboxylate transporters (MCTs). The role of MCTs in the survival of colorectal cancer (CRC) cells is scarce and poorly understood. In this study, we aimed to better understand this issue and exploit these transporters as novel therapeutic targets alone or in combination with the CRC classical chemotherapeutic drug 5-Fluorouracil. For that purpose, we characterized the effects of MCT activity inhibition in normal and CRC derived cell lines and assessed the effect of MCT inhibition in combination with 5-FU. Here, we demonstrated that MCT inhibition using CHC (a-cyano-4-hydroxycinnamic acid), DIDS (4,4'-diisothiocyanatostilbene-2,2'-disulphonic acid) and quercetin decreased cell viability, disrupted the glycolytic phenotype, inhibited proliferation and enhanced cell death in CRC cells. These results were confirmed by specific inhibition of MCT1/4 by RNA interference. Notably, we showed that 5-FU cytotoxicity was potentiated by lactate transport inhibition in CRC cells, either by activity inhibition or expression silencing. These findings provide novel evidence for the pivotal role of MCTs in CRC maintenance and survival, as well as for the use of these transporters as potential new therapeutic targets in combination with CRC conventional therapy.

Sistema de apoio à decisão clínica: quality of life system

Dissertação de mestrado integrado em Engenharia e Gestão de Sistemas de Informação

A presença islâmica na Europa e os desafios postos à prática judicial: Quão conscientes estão os juízes portugueses dos seus preconceitos a respeito do Islão?

Os tribunais – não apenas o TEDH, mas também e sobretudo os tribunais nacionais – têm vindo a assumir um papel importante na integração dos muçulmanos nas sociedades europeias, sendo como são, com crescente frequência, chamados a arbitrar disputas culturais e jurídicas entre a lei estadual e as normas éticas e jurídicas contidas na Lei islâmica (Sharia) e invocadas pelas partes em litígio como fundamento para os comportamentos ou as reivindicações sub judice. Quando as partes no litígio são estrangeiros, a operação das regras de Direito Internacional Privado pode implicar a aplicação de disposições de Direito estrangeiro com fundamento religioso (como acontece, por exemplo, com o Código da Família do Reino de Marrocos, largamente fundado na Lei islâmica), um resultado que só poderá ser afastado se se concluir que a aplicação de tais disposições é contrária a princípios de ordem pública do Estado do foro, tais como o princípio da igualdade entre homens e mulheres. Quando as partes no litígio têm a nacionalidade do Estado do foro, o que é cada vez mais frequente, as normas éticas e jurídicas de origem islâmica poderão ser atendidas ou não pelos tribunais, dependendo do entendimento que os concretos juízes tenham do que sejam o secularismo, a liberdade de religião ou crença, o princípio da igualdade e a proteção dos direitos das minorias.

A estética audiovisual: o caso do Canal 180

Relatório de estágio de mestrado em Ciências da Comunicação (área de especialização em Audiovisual e Multimédia)