1 resultado para Organization of Children’s Memories
em Institutional Repository of Leibniz University Hannover
Filtro por publicador
- KUPS-Datenbank - Universität zu Köln - Kölner UniversitätsPublikationsServer (1)
- Repository Napier (1)
- Aberystwyth University Repository - Reino Unido (1)
- Academic Research Repository at Institute of Developing Economies (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (1)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (1)
- Aquatic Commons (24)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (1)
- Archive of European Integration (141)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (4)
- Aston University Research Archive (11)
- B-Digital - Universidade Fernando Pessoa - Portugal (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (9)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (5)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (2)
- Biodiversity Heritage Library, United States (1)
- Bioline International (2)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (30)
- Boston University Digital Common (6)
- Brock University, Canada (2)
- Bucknell University Digital Commons - Pensilvania - USA (3)
- Bulgarian Digital Mathematics Library at IMI-BAS (4)
- CaltechTHESIS (5)
- Cambridge University Engineering Department Publications Database (12)
- CentAUR: Central Archive University of Reading - UK (15)
- Center for Jewish History Digital Collections (3)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (45)
- Cochin University of Science & Technology (CUSAT), India (1)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (49)
- CORA - Cork Open Research Archive - University College Cork - Ireland (8)
- Corvinus Research Archive - The institutional repository for the Corvinus University of Budapest (1)
- Dalarna University College Electronic Archive (3)
- Deakin Research Online - Australia (21)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (3)
- Digital Commons - Michigan Tech (1)
- Digital Commons at Florida International University (3)
- DigitalCommons@The Texas Medical Center (10)
- DigitalCommons@University of Nebraska - Lincoln (3)
- Duke University (29)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (3)
- Greenwich Academic Literature Archive - UK (1)
- Helda - Digital Repository of University of Helsinki (19)
- Illinois Digital Environment for Access to Learning and Scholarship Repository (1)
- Indian Institute of Science - Bangalore - Índia (42)
- Institutional Repository of Leibniz University Hannover (1)
- Massachusetts Institute of Technology (2)
- Ministerio de Cultura, Spain (2)
- National Center for Biotechnology Information - NCBI (45)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (1)
- Portal de Revistas Científicas Complutenses - Espanha (3)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (59)
- Queensland University of Technology - ePrints Archive (100)
- Repositório Institucional da Universidade Federal do Rio Grande do Norte (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (46)
- Research Open Access Repository of the University of East London. (1)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (1)
- School of Medicine, Washington University, United States (2)
- Universidad Autónoma de Nuevo León, Mexico (1)
- Universidad de Alicante (2)
- Universidad del Rosario, Colombia (2)
- Universidad Politécnica de Madrid (4)
- Universidade Complutense de Madrid (4)
- Universidade de Lisboa - Repositório Aberto (1)
- Universidade Federal do Rio Grande do Norte (UFRN) (4)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (1)
- Université de Lausanne, Switzerland (2)
- Université de Montréal, Canada (3)
- University of Connecticut - USA (3)
- University of Michigan (94)
- University of Queensland eSpace - Australia (13)
- University of Washington (2)
- WestminsterResearch - UK (1)
Resumo:
Collagen is the most abundant protein in the animal kingdom. It is of fundamental importance during development for cell differentiation and tissue morphogenesis as well as in pathological processes such as fibrosis and cancer cell migration. However, our understanding of the mechanisms of procollagen secretion remains limited. Here, we show that TFG organizes transitional ER (tER) and ER exit sites (ERESs) into larger structures. Depletion of TFG results in dispersion of tER elements that remain associated with individual ER-Golgi intermediate compartments (ERGICs) as largely functional ERESs. We show that TFG is not required for the transport and packaging of small soluble cargoes but is necessary for the export of procollagen from the ER. Our work therefore suggests a key relationship between the structure and function of ERESs and a central role for TFG in optimizing COPII assembly for procollagen export.