1 resultado para COLLAGEN MATRICES
em Institutional Repository of Leibniz University Hannover
Filtro por publicador
- Aberystwyth University Repository - Reino Unido (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (4)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (5)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (3)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (3)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (3)
- Argos - Repositorio Institucional de la Secretaría de Investigación y Postgrado de la Facultad de Humanidades y Ciencias Sociales de la Universidad Nacional de Misiones (1)
- Aston University Research Archive (32)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (24)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (20)
- Biblioteca Digital de Artesanías de Colombia (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (63)
- Boston University Digital Common (1)
- Brock University, Canada (3)
- Bulgarian Digital Mathematics Library at IMI-BAS (16)
- CaltechTHESIS (4)
- Cambridge University Engineering Department Publications Database (35)
- CentAUR: Central Archive University of Reading - UK (68)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (23)
- Cochin University of Science & Technology (CUSAT), India (8)
- Coffee Science - Universidade Federal de Lavras (1)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (6)
- CORA - Cork Open Research Archive - University College Cork - Ireland (2)
- Corvinus Research Archive - The institutional repository for the Corvinus University of Budapest (11)
- CUNY Academic Works (16)
- Deakin Research Online - Australia (28)
- Department of Computer Science E-Repository - King's College London, Strand, London (2)
- Digital Commons - Michigan Tech (2)
- Digital Commons @ DU | University of Denver Research (1)
- Digital Commons at Florida International University (5)
- DigitalCommons@The Texas Medical Center (16)
- DRUM (Digital Repository at the University of Maryland) (1)
- Duke University (2)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (1)
- FUNDAJ - Fundação Joaquim Nabuco (1)
- Funes: Repositorio digital de documentos en Educación Matemática - Colombia (2)
- Glasgow Theses Service (1)
- Helda - Digital Repository of University of Helsinki (10)
- Indian Institute of Science - Bangalore - Índia (37)
- Institutional Repository of Leibniz University Hannover (1)
- Instituto de Engenharia Nuclear, Brazil - Carpe dIEN (4)
- INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES (IPEN) - Repositório Digital da Produção Técnico Científica - BibliotecaTerezine Arantes Ferra (2)
- Instituto Politécnico de Bragança (1)
- Instituto Politécnico do Porto, Portugal (3)
- Memoria Académica - FaHCE, UNLP - Argentina (12)
- Ministerio de Cultura, Spain (7)
- National Center for Biotechnology Information - NCBI (22)
- Nottingham eTheses (2)
- Publishing Network for Geoscientific & Environmental Data (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (77)
- Queensland University of Technology - ePrints Archive (134)
- RCAAP - Repositório Científico de Acesso Aberto de Portugal (2)
- Repositorio Academico Digital UANL (1)
- Repositório Científico da Universidade de Évora - Portugal (1)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (1)
- Repositório Institucional da Universidade de Aveiro - Portugal (3)
- Repositório Institucional da Universidade Federal do Rio Grande do Norte (1)
- Repositorio Institucional de la Universidad de El Salvador (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (115)
- Repositorio Institucional Universidad de Medellín (2)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (1)
- SAPIENTIA - Universidade do Algarve - Portugal (1)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (2)
- School of Medicine, Washington University, United States (4)
- Scielo España (1)
- Scientific Open-access Literature Archive and Repository (1)
- Universidad Autónoma de Nuevo León, Mexico (3)
- Universidad de Alicante (6)
- Universidad del Rosario, Colombia (2)
- Universidad Politécnica de Madrid (6)
- Universidade Complutense de Madrid (3)
- Universidade Federal do Rio Grande do Norte (UFRN) (2)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (1)
- Université de Lausanne, Switzerland (1)
- Université de Montréal (2)
- Université de Montréal, Canada (13)
- University of Connecticut - USA (3)
- University of Michigan (7)
- University of Queensland eSpace - Australia (20)
- University of Southampton, United Kingdom (1)
Resumo:
Collagen is the most abundant protein in the animal kingdom. It is of fundamental importance during development for cell differentiation and tissue morphogenesis as well as in pathological processes such as fibrosis and cancer cell migration. However, our understanding of the mechanisms of procollagen secretion remains limited. Here, we show that TFG organizes transitional ER (tER) and ER exit sites (ERESs) into larger structures. Depletion of TFG results in dispersion of tER elements that remain associated with individual ER-Golgi intermediate compartments (ERGICs) as largely functional ERESs. We show that TFG is not required for the transport and packaging of small soluble cargoes but is necessary for the export of procollagen from the ER. Our work therefore suggests a key relationship between the structure and function of ERESs and a central role for TFG in optimizing COPII assembly for procollagen export.