Structure and Conformation of an Antidepressant Drug, Nitroxazepine Hydrochloride Monohydrate

CIsH20N3Oa+.C1-.H2 O, M r = 395, orthorhombic, Pn21a, a = 7.710 (4), b = 11.455 (3), c -- 21.199 (3)/k, Z = 4, V = 1872.4/k 3, D m = 1.38, D C = 1.403 g cm -3, F(000) = 832, g(Cu Kct) = 20.94 cm -l. Intensities for 1641 reflections were measured on a Nonius CAD-4 diffractometer; of these, 1470 were significant. The structure was solved by direct methods and refined to an R index of 0.045 using a blockdiagonal least-squares procedure. The angle between the least-squares planes through the benzene rings is 125.0 (5) ° and the side chain is folded similarly to one of the independent molecules of imipramine hydrochloride.

Structure and conformation of an anti-depressant drug, nitroxazepine hydrochloride monohydrate

CIsH20N3Oa+.C1-.H2 O, M r = 395, orthorhombic, Pn21a, a = 7.710 (4), b = 11.455 (3), c -- 21.199 (3)/k, Z = 4, V = 1872.4/k 3, D m = 1.38, D C = 1.403 g cm -3, F(000) = 832, g(Cu Kct) = 20.94 cm -l. Intensities for 1641 reflections were measured on a Nonius CAD-4 diffractometer; of these, 1470 were significant. The structure was solved by direct methods and refined to an R index of 0.045 using a blockdiagonal least-squares procedure. The angle between the least-squares planes through the benzene rings is 125.0 (5) ° and the side chain is folded similarly to one of the independent molecules of imipramine hydrochloride.

Revalidation of Natrix clerki Wall, 1925, an overlooked species in the genus Amphiesma Dumeril, Bibron & Dumeril, 1854 (Squamata: Natricidae)

Natrix clerki Wall, 1925, previously known from its sole holotype and considered a synonym of Amphiesma parallelum (Boulenger, 1890), is resurrected in the genus Amphiesma on the basis of the analysis of morphological variation in 28 specimens of ``Amphiesma parallelum'' auctorum, plus six living, unvouchered specimens discovered in Arunachal Pradesh and Nagaland, India, and one vouchered specimen from Talle Valley in Arunachal Pradesh. Specimens from northeast India (Nagaland), northern Myanmar, and China (Yunnan), previously identified as Amphiesma parallelum either in the literature or in museum's catalogues, are also here referred to A. clerki. The holotype of Amphiesma clerki is redescribed. As a consequence, the definition of Amphiesma parallelum is modified. A. parallelum inhabits the Khasi Hills and Naga Hills in Northeast India, whereas A. clerki has a wider range in the Eastern Himalayas, northern Myanmar and Yunnan (China). Amphiesma clerki differs from A. parallelum by its longer tail, dorsal scales more strongly keeled, scales of the first dorsal scale row strongly keeled vs. smooth, a postocular streak not interrupted at the level of the neck, and a much more vivid pattern on a darker background colour. Characters of species of the Amphiesma parallelum group, i.e. A. clerki, A. parallelum, A. bitaeniatum, A. platyceps and A. sieboldii are compared. A key to this group is provided.

Forgotten records of Chrysopelea taprobanica Smith, 1943 (Squamata: Colubridae) from India

The colubrid snake Chrysopelea taprobanica Smith, 1943 was described from a holotype from Kanthali (= Kantalai) and paratypes from Kurunegala, both localities in Sri Lanka (formerly Ceylon) (Smith 1943). Since its description, literature pertaining to Sri Lankan snake fauna considered this taxon to be endemic to the island (Taylor 1950, Deraniyagala 1955, de Silva 1980, de Silva 1990, Somaweera 2004, Somaweera 2006, de Silva 2009, Pyron et al. 2013). In addition, earlier efforts on the Indian peninsula (e.g. Das 1994, 1997, Das 2003, Whitaker & Captain 2004, Aengals et al. 2012) and global data compilations (e.g. Wallach et al. 2014, Uetz & Hošek 2015) did not identify any record from mainland India until Guptha et al. (2015) recorded a specimen (voucher BLT 076 housed at Bio-Lab of Seshachalam Hills, Tirupathi, India) in the dry deciduous forest of Chamala, Seshachalam Biosphere Reserve in Andhra Pradesh, India in November 2013. Guptha et al. (2015) further mentioned an individual previously photographed in 2000 at Rishi Valley, Andhra Pradesh, but with no voucher specimen collected. Guptha’s record, assumed to be the first confirmed record of C. taprobanica in India, is noteworthy as it results in a large range extension, from northern Sri Lanka to eastern India with an Euclidean distance of over 400 km, as well as a change of status, i.e., species not endemic to Sri Lanka. However, at least three little-known previous records of this species from India evaded most literature and were overlooked by the researchers including ourselves.