19 resultados para 141-863
em Helda - Digital Repository of University of Helsinki
Resumo:
Abstract This dissertation is a cross-linguistic study of lexical iconicity. The study is based on a genealogically stratified sample of 237 languages. The aim is to contribute with an empirical study to the growing dialogue focusing on different forms of lexical iconicity. The conceptual framework of the present study is based on an analysis of types and means of lexical iconicity in the sample languages. Archaeological and cultural evidence are used to tie lexical iconicity to its context. Phenomena related to lexical iconicity are studied both cross-linguistically and language-specifically. The cognitive difference between imitation and symbolism is essential. Lexical iconicity is not only about the iconic relationship between form and referents, but also about how certain iconic properties may become conventional, means used to create sound symbolism. All the sample languages show some evidence of lexical iconicity, demonstrating that it is a universal feature. Nine comparisons of onomatopoeic verbs and nouns, with samples varying between six and 141 languages, show that typologically highly different languages use similar means for creating words based on sound imitation. Two cross-linguistic comparisons of bird names demonstrate that a vast majority of the Eurasian names of the common cuckoo and the world-wide names of crow and raven of the 141 genera are onomatopoeic.
Resumo:
Theory of developmental origins of adult health and disease proposes that experiences during critical periods of early development may have consequences on health throughout a lifespan. Thesis studies aimed to characterize associations between early growth and some components of the metabolic syndrome cluster. Participants belong to two epidemiological cohorts with data on birth measurements and, for the younger cohort, on serial recordings of weight and height during childhood. They were born as singletons between 1924-33 and 1934-44 in the Helsinki University Central Hospital, and 500 and 2003 of them, respectively, attended clinical studies at the age of 65-75 and 56-70 years, respectively. In the 65-75 year old men and women, the well-known inverse relationship between birth weight and systolic blood pressure (SBP) was confined to people who had established hypertension. Among them a 1-kg increase in birth weight was associated with a 6.4-mmHg (95% CI: 1.0 to 11.9) decrease in SBP. This relationship was further confined to people with the prevailing Pro12Pro polymorphism of the peroxisome proliferator-activated receptor-γ2 (PPARγ2) gene. People with low birth weight were more likely to receive angiotensin-converting enzyme inhibitors/angiotensin-receptor blockers (ACEI/ARB, p=0.03), and, again, this relationship was confined to the carriers of the Pro12Pro (p=0.01 for interaction). These results suggest that the inverse association between birth weight and systolic BP becomes focused in hypertensive people because pathological features of BP regulation, associated with slow fetal growth, become self-perpetuating in adult life. Insulin resistance of the Pro12Pro carriers with low birth weight may interact with the renin-angiotensin system leading to raised BP levels. Habitual physical activity protected men and women who were small at birth, and thus at increased risk for the development of type 2 diabetes, against glucose intolerance more strongly. Among subjects with birth weight ≤3000 g, the odds ratio (OR) for glucose intolerance was 5.2 (95% CI: 2.1 to 13) in those who exercised less than 3 times per week compared to regular exercisers; in those who scored their exercise light compared with moderate exercisers (defined as comparable to brisk walking) the OR was 3.5 (1.5 to 8.2). In the 56-70 year old men a 1 kg increase in birth weight corresponded to a 4.1 kg (95% CI: 3.1 to 5.1) and in women to a 2.9 kg (2.1 to 3.6) increase in adult lean mass. Rapid gain in body mass index (BMI), i.e. crossing from an original BMI percentile to a higher one, before the age of 2 years increased adult lean mass index (LMI, lean mass/height squared) without excess fat accumulation whereas rapid gain in BMI during later childhood, despite the concurrent rise in LMI, resulted in a relatively higher increase in adult body fat mass. These findings illustrate how genes, the environment and their interactions, early growth patterns, and adult lifestyle modify adult health risks which originate from early life.
Resumo:
The chemical composition of breast milk has been studied in detail in the past decades. Hundreds of new antibacterial and antiviral components have been found. Several molecules have been found to promote the proper function of neonatal intestine. However, microbiological studies of breast milk have been, until recently, focused mainly on detecting harmful and pathogenic bacteria and viruses. Natural microbial diversity of human milk has not been widely studied before the work reported in this thesis. This is mainly because breast milk has traditionally been thought to be sterile - even if a certain amount of commensal bacteria have usually been detected in milk samples. The first part of this licentiate thesis contains a short literature review about the anatomy and physiology of breast feeding, human milk chemical and microbiological composition, mastitis, intestinal flora and bacteriocins. The second part reports on the experiments of the licentiate work, concentrating on the microbial diversity in the milk of healthy breast-feeding mothers, and the ability of these bacteria to produce antibacterial substances against pathogenic bacteria. The results indicate that human milk is a source of commensal bacteria for infant intestine. 509 random isolates from 40 breast milk samples were isolated and identified by 16S rRNA sequencing. Median bacterial count was about 600 colony forming units per milliliter. Over half of the isolates were staphylococci, and almost one third streptococci. The most common species were skin bacteria Staphylococcus epidermidis and oral bacteria Streptococcus salivarius and Streptococcus mitis. Lactic acid bacteria, identified as members of Lactobacillus-, Lactococcus- and Leuconostoc -genera, were found in five milk samples. Enterococci were found in three samples. A novel finding in this study is the capability of these commensal bacteria to inhibit the growth of pathogens. In 90 precent of the milk samples commensal bacteria inhibiting the growth of Staphylococcus aureus were found. In 40 precent of samples the colonies could block the growth completely. One fifth of the isolated Staph. epidermidis strains, half of Str. salivarius strains, and all lactic acid bacteria and enterococci could inhibit or block the growth of Staph. aureus. In further study also Listeria innocua- and Micrococcus luteus active isolates were found in 33 and 11 precent of milk samples (out of 140). Furthermore, two Lactococcus lactis isolates from the breast milk were shown to produce bacteriocin nisin, which is an antimicrobial molecule used as a food preservative. The importance of these human milk commensal bacteria in the development of newborn intestinal flora and immune system, as well as in preventing maternal breast infections, should be further explored.
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This study of the Finns at the International Lenin School (ILS) reflects history of the Soviet Union during Stalin's era, history of the Communist International (Comintern) as well as history of Finnish communism. The life span of the ILS (1926-1938) matches up with creating and establishing the power structures of Stalinism. Both the ILS and Finnish Communism in the USSR became casualties of the Great Terror (1937-1938). After the WW2, however, the Soviet education was appreciated inside the Communist Party of Finland (CPF). If Finland would have become People's Democracy, the former ILS students would have composed the inner circle of the new "democratic" government. The Finnish teachers of the ILS were leaders of the CPF that was headquartered in Moscow. At the ILS studied in total 141 Finnish communists. The purpose of the ILS was to educate the communist parties' leading stratum of functionaries. They were supposed to internalize current values, methods and discipline of the Bolsheviks. This study evaluates the effects of the total school experience on the Finns that often ended in another total institution in Finland: prison. The curricula of the ILS consisted of theory of Marxism-Leninism, party history, political economics and themes of campaigns of Stalinism. The ILS year included participation in Bolshevik party life and practical work. During summer excursions (praktikas) the students could acquaint themselves with building of socialism in the Soviet Republics. At the ILS, intention to ideological moulding was not hidden. The students were supposed to adopt the Stalinist identity of the professional revolutionaries of the era. The ILS was saturated with ideology and propaganda. This study analyzes especially uses of history as vehicle of ideological standardisation and as instrument of power. Stalin contributed personally to shortcomings of history writing of the communist party. Later he supervised writing of the inclusive handbook of communism, "History of the All-Union Communist Party. Short Course". Special attention will be paid to the effects of Stalin's intervention at the ILS and inside the CPF. The life of the Finns at the ILS and outside the school is described at grass roots. The dividing line between personal and political is analyzed by charting emotional, intimate and bodily experiences of the Finns of the ILS. The fates of the ILS Finns after the studying or teaching period in Moscow are explored in detail. The protagonist among the teachers is Yrjö Sirola that was called "father of the CPF cadres". The Finnish ILS teachers and the formed students that had remained in the USSR were most severely hit by the Great Terror. The Soviet education had most importance in Finland of post WW2 period. The training at the ILS, however, did not contribute to revolution in Finland. The main heading of the study, "A Short Course of Stalinism", crystallises interpretation of the ILS as seat of learning of ideological unity of Stalinism. On the other hand, the title includes a statement of incompleteness of the Stalinist education if the schooling at the ILS had remained in one year.
Resumo:
Background: The incidence of all forms of congenital heart defects is 0.75%. For patients with congenital heart defects, life-expectancy has improved with new treatment modalities. Structural heart defects may require surgical or catheter treatment which may be corrective or palliative. Even those with corrective therapy need regular follow-up due to residual lesions, late sequelae, and possible complications after interventions. Aims: The aim of this thesis was to evaluate cardiac function before and after treatment for volume overload of the right ventricle (RV) caused by atrial septal defect (ASD), volume overload of the left ventricle (LV) caused by patent ductus arteriosus (PDA), and pressure overload of the LV caused by coarctation of the aorta (CoA), and to evaluate cardiac function in patients with Mulibrey nanism. Methods: In Study I, of the 24 children with ASD, 7 underwent surgical correction and 17 percutaneous occlusion of ASD. Study II had 33 patients with PDA undergoing percutaneous occlusion. In Study III, 28 patients with CoA underwent either surgical correction or percutaneous balloon dilatation of CoA. Study IV comprised 26 children with Mulibrey nanism. A total of 76 healthy voluntary children were examined as a control group. In each study, controls were matched to patients. All patients and controls underwent clinical cardiovascular examinations, two-dimensional (2D) and three-dimensional (3D) echocardiographic examinations, and blood sampling for measurement of natriuretic peptides prior to the intervention and twice or three times thereafter. Control children were examined once by 2D and 3D echocardiography. M-mode echocardiography was performed from the parasternal long axis view directed by 2D echocardiography. The left atrium-to-aorta (LA/Ao) ratio was calculated as an index of LA size. The end-diastolic and end-systolic dimensions of LV as well as the end-diastolic thicknesses of the interventricular septum and LV posterior wall were measured. LV volumes, and the fractional shortening (FS) and ejection fraction (EF) as indices of contractility were then calculated, and the z scores of LV dimensions determined. Diastolic function of LV was estimated from the mitral inflow signal obtained by Doppler echocardiography. In three-dimensional echocardiography, time-volume curves were used to determine end-diastolic and end-systolic volumes, stroke volume, and EF. Diastolic and systolic function of LV was estimated from the calculated first derivatives of these curves. Results: (I): In all children with ASD, during the one-year follow-up, the z score of the RV end-diastolic diameter decreased and that of LV increased. However, dilatation of RV did not resolve entirely during the follow-up in either treatment group. In addition, the size of LV increased more slowly in the surgical subgroup but reached control levels in both groups. Concentrations of natriuretic peptides in patients treated percutaneously increased during the first month after ASD closure and normalized thereafter, but in patients treated surgically, they remained higher than in controls. (II): In the PDA group, at baseline, the end-diastolic diameter of LV measured over 2SD in 5 of 33 patients. The median N-terminal pro-brain natriuretic peptide (proBNP) concentration before closure measured 72 ng/l in the control group and 141 ng/l in the PDA group (P = 0.001) and 6 months after closure measured 78.5 ng/l (P = NS). Patients differed from control subjects in indices of LV diastolic and systolic function at baseline, but by the end of follow-up, all these differences had disappeared. Even in the subgroup of patients with normal-sized LV at baseline, the LV end-diastolic volume decreased significantly during follow-up. (III): Before repair, the size and wall thickness of LV were higher in patients with CoA than in controls. Systolic blood pressure measured a median 123 mm Hg in patients before repair (P < 0.001) and 103 mm Hg one year thereafter, and 101 mm Hg in controls. The diameter of the coarctation segment measured a median 3.0 mm at baseline, and 7.9 at the 12-month (P = 0.006) follow-up. Thicknesses of the interventricular septum and posterior wall of the LV decreased after repair but increased to the initial level one year thereafter. The velocity time integrals of mitral inflow increased, but no changes were evident in LV dimensions or contractility. During follow-up, serum levels of natriuretic peptides decreased correlating with diastolic and systolic indices of LV function in 2D and 3D echocardiography. (IV): In 2D echocardiography, the interventricular septum and LV posterior wall were thicker, and velocity time integrals of mitral inflow shorter in patients with Mulibrey nanism than in controls. In 3D echocardiography, LV end-diastolic volume measured a median 51.9 (range 33.3 to 73.4) ml/m² in patients and 59.7 (range 37.6 to 87.6) ml/m² in controls (P = 0.040), and serum levels of ANPN and proBNP a median 0.54 (range 0.04 to 4.7) nmol/l and 289 (range 18 to 9170) ng/l, in patients and 0.28 (range 0.09 to 0.72) nmol/l (P < 0.001) and 54 (range 26 to 139) ng/l (P < 0.001) in controls. They correlated with several indices of diastolic LV function. Conclusions (I): During the one-year follow-up after the ASD closure, RV size decreased but did not normalize in all patients. The size of the LV normalized after ASD closure but the increase in LV size was slower in patients treated surgically than in those treated with the percutaneous technique. Serum levels of ANPN and proBNP were elevated prior to ASD closure but decreased thereafter to control levels in patients treated with the percutaneous technique but not in those treated surgically. (II): Changes in LV volume and function caused by PDA disappeared by 6 months after percutaneous closure. Even the children with normal-sized LV benefited from the procedure. (III): After repair of CoA, the RV size and the velocity time integrals of mitral inflow increased, and serum levels of natriuretic peptides decreased. Patients need close follow-up, despite cessation of LV pressure overload, since LV hypertrophy persisted even in normotensive patients with normal growth of the coarctation segment. (IV): In children with Mulibrey nanism, the LV wall was hypertrophied, with myocardial restriction and impairment of LV function. Significant correlations appeared between indices of LV function, size of the left atrium, and levels of natriuretic peptides, indicating that measurement of serum levels of natriuretic peptides can be used in the clinical follow-up of this patient group despite its dependence on loading conditions.
Resumo:
Argues that as a more effective precuationary measure, it would seem that the firearms revocation threshold should be substantially lowered, or at least further clarified in guidance. Response to public debate in light of school shootings.
Resumo:
Background and aims: Low stage and curative surgery are established factors for improved survival in gastric cancer. However, not all low-stage patients have a good prognosis. Cyclooxygenase-2 (COX-2) is known to associate with reduced survival in several cancers, and has been shown to play an important role in gastric carcinogenesis. Since new and better prognostic markers are needed for gastric cancer, we studied the prognostic significance of COX-2 and of markers that associate with COX-2 expression. We also studied markers reflecting proliferation and apoptosis, and evaluated their association with COX-2. Our purpose was to construct an accurate prognostic model by combining tissue markers and clinicopathogical factors. Materials and methods: Of 342 consecutive patients who underwent surgery for gastric cancer at Meilahti Hospital, Helsinki University Central Hospital, 337 were included in this study. Low stages I to II were represented by 141 (42%) patients, and high stages III to IV by 196 (58%). Curative surgery was performed on 176 (52%) patients. Survival data were obtained from the national registers. Slides from archive tissue blocks were prepared for immunohistochemistry by use of COX-2, human antigen R (HuR), cyclin A, matrix metalloproteinases 2 and 9 (MMP-2, MMP-9), and Ki-67 antibodies. Immunostainings were scored by microscopy, and scores were entered into a database. Associations of tumor markers with clinicopathological factors were calculated, as well as associations with p53, p21, and results of flow cytometry from earlier studies. Survival analysis was performed by the Kaplan-Meier method, and Cox multivariate models were reconstructed. Cell culture experiments were performed to explore the effect of small interfering (si)RNA of HuR on COX-2 expression in a TMK-1 gastric cancer cell line. Results: Overall 5-year survival was 35.1%. Study I showed that COX-2 was an independent prognostic factor, and that the prognostic impact of COX-2 was more pronounced in low-stage patients. Cytoplasmic HuR expression also associated with reduced survival in gastric cancer patients in a non-independent manner. Cell culture experiments showed that HuR can regulate COX-2 expression in TMK-1 cells in vitro, with an association also between COX-2 and HuR tissue expression in a clinical material. In Study II, cyclin A was an independent prognostic factor and was associated with HuR expression in the gastric cancer material. The results of Study III showed that epithelial MMP-2 associated with survival in univariate, but not in multivariate analysis. However, MMP-9 showed no prognostic value. MMP-2 expression was associated with COX-2 expression. In Study IV, the prognostic power of COX-2 was compared with that of all tested markers associated with survival in Studies I to III, as well as with p21, p53, and flow cytometry results. COX-2 and p53 were independent prognostic factors, and COX-2 expression was associated with that of p53 and Ki-67 and also with aneuploidy. Conclusions: COX-2 is an independent prognostic factor in gastric cancer, and its prognostic power emerges especially in low stage cancer. COX-2 is regulated by HuR, and is associated with factors reflecting invasion, proliferation, and apoptosis. In an extended multivariate model, COX-2 retained its position as an independent prognosticator. COX-2 can be considered a promising new prognostic marker in gastric cancer.
Resumo:
The purpose of this thesis is to examine the role of trade durations in price discovery. The motivation to use trade durations in the study of price discovery is that durations are robust to many microstructure effects that introduce a bias in the measurement of returns volatility. Another motivation to use trade durations in the study of price discovery is that it is difficult to think of economic variables, which really are useful in the determination of the source of volatility at arbitrarily high frequencies. The dissertation contains three essays. In the first essay, the role of trade durations in price discovery is examined with respect to the volatility pattern of stock returns. The theory on volatility is associated with the theory on the information content of trade, dear to the market microstructure theory. The first essay documents that the volatility per transaction is related to the intensity of trade, and a strong relationship between the stochastic process of trade durations and trading variables. In the second essay, the role of trade durations in price discovery is examined with respect to the quantification of risk due to a trading volume of a certain size. The theory on volume is intrinsically associated with the stock volatility pattern. The essay documents that volatility increases, in general, when traders choose to trade with large transactions. In the third essay, the role of trade durations in price discovery is examined with respect to the information content of a trade. The theory on the information content of a trade is associated with the theory on the rate of price revisions in the market. The essay documents that short durations are associated with information. Thus, traders are compensated for responding quickly to information
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In this paper, we examine the predictability of observed volatility smiles in three major European index options markets, utilising the historical return distributions of the respective underlying assets. The analysis involves an application of the Black (1976) pricing model adjusted in accordance with the Jarrow-Rudd methodology as proposed in 1982. Thereby we adjust the expected future returns for the third and fourth central moments as these represent deviations from normality in the distributions of observed returns. Thus, they are considered one possible explanation to the existence of the smile. The obtained results indicate that the inclusion of the higher moments in the pricing model to some extent reduces the volatility smile, compared with the unadjusted Black-76 model. However, as the smile is partly a function of supply, demand, and liquidity, and as such intricate to model, this modification does not appear sufficient to fully capture the characteristics of the smile.
Resumo:
Tiivistelmä Mobiilius on nopeasti kehittyvässä teknologiassa yksi merkittävimmistä ominaisuuksista tiedonvälitykselle ja tiedon käsittelyn käytänteille. Mobiiliudella tarkoitetaan liikkuvuutta, joka voidaan liittää oppilaan fyysiseen liikkuvuuteen tai työskentelyn mahdollisuuteen missä ja milloin tahansa tietotekniikan keinoin. Tässä artikkelissa tarkastellaan mobiililaitteiden käyttöä digitaaliseen portfoliotyöskentelyyn liittyvässä oppilaslähtöisessä sisällöntuotannossa. Artikkeli on osa laajempaa design-tutkimusta, jonka tavoitteena on löytää keinoja oppimisprosessin tukemiseksi monimuotoisessa etäopetusympäristössä perusasteen vieraiden kielten opetuksessa. Tuloksista voidaan todeta, että sisällöntuotanto digitaalisiin portfolioihin osoittautui itseohjautuvuutta tukevaksi pedagogiseksi ratkaisuksi. Mobiilius ajan ja erityisesti paikan suhteen merkitsee mahdollisuutta ja joustavuutta tilanteessa, jossa oppilaat opiskelevat fyysisesti ja virtuaalisesti eri tiloissa. Tutkimuksen tuloksia voidaan hyödyntää oppivan tietoyhteiskunnan teknologiakäytänteiden vakiinnuttamisessa koulun arjessa.
Resumo:
Osteokondroosi (OC) on hevosten ortopedisistä kehityshäiriöistä yleisin kirurgiaa vaativa sairaustila. Se on sairautena monelta osin vielä hyvin epäselvä. Perinnöllisyyden osuus sen ilmentymisessä on noin 25 %. Suomenhevosilla OC:n esiintyvyyttä ei ole tutkittu, mutta sen osuuden epäillään kasvavan jatkuvasti. Suomessa pääsääntöisesti vain juoksijasuuntaan kantakirjatun suomenhevosorin jälkeläinen voi saada ravikilpailuoikeuden. Kantakirjauksen yhteydessä tehdyn röntgentutkimuksen avulla OC:ta sairastavat yksilöt voidaan hylätä ja siten sulkea pois jalostuksesta. Tästä käytännöstä voidaan poiketa, mikäli orilla on poikkeuksellisen hyviä kilpailutuloksia. Tämän tutkimuksen tavoitteena oli selvittää, onko OC:ta sairastavien orien hyväksyminen kantakirjaan riski suomenhevosravureiden tulevien sukupolvien kilpailumenestykselle. Tutkimusta oli kohorttitutkimus, jossa kilpailumenestyksen mittareina käytettiin starttistatusta, starttien määrää, sijoituksia, voittosummia, ennätysaikoja, hylkäyksiä, keskeytyksiä sekä kilpailupöytäkirjoihin kirjattuja laukka- ja epäpuhdas ravi – merkintöjä. Tutkimuksessa verrattiin suomenhevosravurien, joiden isällä on OC, kilpailumenestystä niiden suomenhevosravurien kilpailumenestykseen, joiden isäoriit oli kantakirjauksen yhteydessä todettu jaloistaan terveiksi (OC-vapaiksi). OC:lle altistuneista jälkeläisistä koostuvan ryhmän isäoreiksi valittiin kaikki juoksijasuuntaiset, OC:ta sairastavat suomenhevosoriit. OC:ta sairastavien orien jälkeläisiä oli tutkimuksessa mukana 435 ja OC-vapaiden orien jälkeläisiä 863. Aineistolle tehtiin tilastollinen analyysi Pearsonin χ²-testiä ja varianssianalyysia käyttäen. Voima-analyysi tehtiin jälkikäteen, jolloin todettiin, että tutkimuksen voima todeta havaittuja eroja oli parhaimmillaankin vain 50 % tasolla. Tuloksista ainoa tilastollisesti merkitsevä ero löytyi verrattaessa ravikilpailuissa startanneiden jälkeläisten osuuksia edellä mainituissa ryhmissä. OC:ta sairastavien isäorien jälkeläisistä yhteen tai useampaan ravikilpailulähtöön oli osallistunut 40,2 % hevosista, kun vastaava luku OC-vapaiden isäorien jälkeläisryhmässä oli 34,6 % (p=0,049). Vaikka muut tulokset olivatkin tilastollisesti merkityksettömiä, saattavat ne antaa viitteitä siitä, että OC:ta sairastavien orien jälkeläisten ura on lyhyempi, mutta mahdollisesti menestyksekkäämpi kuin OC-vapaiden orien jälkeläisillä. Tutkimuksen tulokset ja erityisesti niiden vertaaminen aiempiin tutkimuksiin tukevat käsitystä siitä, että OC periytyy mahdollisesti yhdessä hyvään juoksukykyyn liittyvien ominaisuuksien kanssa. Lisäksi tutkimus kyseenalaistaa, onko suomenhevosravurien kantakirjauksesta poissulkeminen tarkoituksenmukaista OC:n perusteella. Kyseessä on etiologialtaan ja diagnoosin kannalta hyvin haastava sairaus, jolla ei aina ole kliinistä merkitystä.
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Tutkimuksessa tarkasteltiin inkerinsuomalaisten muuttoa edeltävien odotusten toteutumisen yhteyttä psykologiseen sopeutumiseen. Psykologisen sopeutumisen indikaattorina käytettiin elämään tyytyväisyyttä. Tutkimuksen tavoitteena oli tuoda esille sopeutumista prosessina, joka alkaa jo ennen muuttoa (pre-akkulturaatio) sekä luoda uutta tietoa paluumuuttajien odotusten toteutumisen vaikutuksesta sopeutumiseen. Toteutuneiden odotusten tutkimuskenttä muodostaa oman tutkimusperinteensä, jonka piirissä on pyritty selvittämään odotusten ja kokemusten välisen suhteen yhteyttä tyytyväisyyteen eri konteksteissa. Akkulturaatiotutkimuksissa korostetaan, että maahanmuuttajien epärealistiset odotukset muuton jälkeisestä elämästä vaikeuttavat sopeutumisprosessia. Tässä pitkittäistutkimuksessa toteutuneiden odotusten yhteyttä elämään tyytyväisyyteen tarkasteltiin paluumuuttokontekstissa kolmen vaihtoehtoisen mallin avulla. Ideaalitaso-mallin mukaan odotusten toteutuminen nostaa elämään tyytyväisyyttä ja toteutumatta jääminen laskee sitä. Ei vahvistusta –mallissa elämään tyytyväisyyden oletetaan olevan korkeimmillaan silloin, kun kokemukset ylittävät odotukset. Vain kokemus –mallin mukaan hyvät kokemukset muuton jälkeen nostavat elämään tyytyväisyyttä odotusten tasosta riippumatta. Malleja testattiin erikseen sosio-psyykkiseen hyvinvointiin ja ammatillis-taloudelliseen hyvinvointiin liittyvien odotusten suhteen. Perhe- ja ystäväsuhteiden laadun sekä ammatillisten mahdollisuuksien ja taloudellisen tilanteen tason on osoitettu olevan yhteydessä elämään tyytyväisyyteen. Maahanmuuttajien odotuksien on niin ikään todettu koskevan näitä elämänlaatua indikoivia osa-alueita. Tutkimuksen aineisto koostui etniseltä taustaltaan inkerinsuomalaisista (N=141) paluumuuttajista. Lähtökohta-aineisto kerättiin Venäjällä ennen muuttoa ja seurantavaihe toteutettiin noin vuosi muuton jälkeen. Aineiston analysoinnissa huomioitiin ajankohtainen metodologiakeskustelu ja kahden muuttujan välisen suhteen vaikutusta riippuvaan muuttujaan tarkasteltiin polynomisen regressioanalyysin ja vastepintamallinnuksen avulla. Näin tehden voitiin välttää toteutuneiden odotusten tutkimuksille tyypilliset mittaus- ja metodologiaongelmat: retrospektiivisyys, erotuspistemäärien käyttö ja lineaaristen mallien käyttö. Tutkimuksen aineisto tuki ei vahvistusta –mallin mukaista yhteyttä odotusten toteutumisen ja elämään tyytyväisyyden välillä. Yhteyttä voitiin tarkastella vain sosio-psyykkiseen hyvinvointiin liittyvien odotusten ja kokemusten suhteen, koska ammatillis-taloudelliseen hyvinvointiin liittyvät odotukset, kokemukset tai niistä muodostetut interaktiotermit eivät polynomisen regressioanalyysin tulosten mukaan olleet yhteydessä elämään tyytyväisyyteen tilastollisesti merkitsevästi. Paluumuuttajien elämään tyytyväisyys oli korkeimmillaan silloin, kun sosio-psyykkiseen hyvinvointiin liittyvät kokemukset ylittivät odotukset. Odotusten ja kokemusten välisen eroavuuden suunnalla siis on tämän tutkimuksen tulosten perusteella merkitystä psykologisen sopeutumisen kannalta. Tutkimuksen tulos tukee näkemystä, jonka mukaan maahanmuuttajien sopeutumisprosessia tulisi tarkastella pitkittäisasetelmassa muuttoa edeltävä vaihe huomioiden. Lisäksi tutkimus avaa yhden näkökulman siihen, minkä elämän osa-alueiden laatu on paluumuuttajien sopeutumisen kannalta merkityksellistä.