The Historical Thesaurus and the sentimental language of Robert Burns

This thesis demonstrates a new methodology for the linguistic analysis of literature drawing on the data within The Historical Thesaurus of the Oxford English Dictionary (2009). Developing ideas laid out by Carol McGuirk in her book Robert Burns and the Sentimental Era (1985), this study offers a novel approach to the cultural connections present in the sentimental literature of the eighteenth century, with specific reference to Robert Burns. In doing so, it responds to the need to “stop reading Burns through glossaries and start reading him through dictionaries, thesauruses and histories”, as called for by Murray Pittock (2012). Beginning by situating the methodology in linguistic theory, this thesis goes on firstly to illustrate the ways in which such an approach can be deployed to assess existing literary critical ideas. The first chapter does this testing by examining McGuirk’s book, while simultaneously grounding the study in the necessary contextual background. Secondly, this study investigates, in detail, two aspects of Burns’s sentimental persona construction. Beginning with his open letter ‘The Address of the Scotch Distillers’ and its sentimental use of the language of the Enlightenment, and moving on to one of Burns’s personas in his letters to George Thomson, this section illustrates the importance of persona construction in Burns’s sentimental ethos. Finally, a comprehensive, evidence-based, comparison of linguistic trends examines the extent to which similar sentimental language is used by Burns and Henry Mackenzie, Laurence Sterne, William Shenstone and Samuel Richardson. This thesis shows how this new methodology is a valuable new tool for those involved in literary scholarship. For the first time in any comprehensive way the Historical Thesaurus can be harnessed to make new arguments in literary criticism.

Aetius of Amida. Libri Medicinales Book 1: A Translation with Commentary

This work is the first translation into a modern language of book 1 of the Libri Medicinales of Aëtius of Amida, a Byzantine physician who wrote in the middle of the 6th century AD. It comprises a lengthy preface, describing the analysis of pharmacological materials in terms of the science of the time, followed by 418 chapters, listing such materials obtained from plants. Commentary is to be found in the Introduction, as well as a running commentary after each part of the preface and each chapter. As Aëtius’ book 1 is a synopsis of the plants section of Galen’s On the Mixtures and Capacities of Simple Drugs, particular attention is paid to comparison between Aëtius’ work and that of Galen. Evaluation of the efficacy and safety of the ancient drugs in the light of modern scientific knowledge, a relatively neglected area of research, has also been given serious consideration.

Neurorehabilitation of hand functions using brain computer interface

Introduction: Brain computer interface (BCI) is a promising new technology with possible application in neurorehabilitation after spinal cord injury. Movement imagination or attempted movement-based BCI coupled with functional electrical stimulation (FES) enables the simultaneous activation of the motor cortices and the muscles they control. When using the BCI- coupled with FES (known as BCI-FES), the subject activates the motor cortex using attempted movement or movement imagination of a limb. The BCI system detects the motor cortex activation and activates the FES attached to the muscles of the limb the subject is attempting or imaging to move. In this way the afferent and the efferent pathways of the nervous system are simultaneously activated. This simultaneous activation encourages Hebbian type learning which could be beneficial in functional rehabilitation after spinal cord injury (SCI). The FES is already in use in several SCI rehabilitation units but there is currently not enough clinical evidence to support the use of BCI-FES for rehabilitation. Aims: The main aim of this thesis is to assess outcomes in sub-acute tetraplegic patients using BCI-FES for functional hand rehabilitation. In addition, the thesis explores different methods for assessing neurological rehabilitation especially after BCI-FES therapy. The thesis also investigated mental rotation as a possible rehabilitation method in SCI. Methods: Following investigation into applicable methods that can be used to implement rehabilitative BCI, a BCI based on attempted movement was built. Further, the BCI was used to build a BCI-FES system. The BCI-FES system was used to deliver therapy to seven sub-acute tetraplegic patients who were scheduled to receive the therapy over a total period of 20 working days. These seven patients are in a 'BCI-FES' group. Five more patients were also recruited and offered equivalent FES quantity without the BCI. These further five patients are in a 'FES-only' group. Neurological and functional measures were investigated and used to assess both patient groups before and after therapy. Results: The results of the two groups of patients were compared. The patients in the BCI-FES group had better improvements. These improvements were found with outcome measures assessing neurological changes. The neurological changes following the use of the BCI-FES showed that during movement attempt, the activation of the motor cortex areas of the SCI patients became closer to the activation found in healthy individuals. The intensity of the activation and its spatial localisation both improved suggesting desirable cortical reorganisation. Furthermore, the responses of the somatosensory cortex during sensory stimulation were of clear evidence of better improvement in patients who used the BCI-FES. Missing somatosensory evoked potential peaks returned more for the BCI-FES group while there was no overall change in the FES-only group. Although the BCI-FES group had better neurological improvement, they did not show better functional improvement than the FES-only group. This was attributed mainly to the short duration of the study where therapies were only delivered for 20 working days. Conclusions: The results obtained from this study have shown that BCI-FES may induce cortical changes in the desired direction at least faster than FES alone. The observation of better improvement in the patients who used the BCI-FES is a good result in neurorehabilitation and it shows the potential of thought-controlled FES as a neurorehabilitation tool. These results back other studies that have shown the potential of BCI-FES in rehabilitation following neurological injuries that lead to movement impairment. Although the results are promising, further studies are necessary given the small number of subjects in the current study.

The influence of neoconservatism on US foreign policy debates during the Obama administration

Neoconservatism reached its zenith as a school of thought when it became associated with the Iraq War. Although the war was largely considered a failure, it raised the profile of neoconservatism as a school of thought. Many studies were completed which pointed to the influence of prominent members of the George W. Bush administration who were considered to be ideologically neoconservative. When Obama won the presidency in 2008, it was assumed that the influence of neoconservatives, or neoconservatism more broadly, would be over. However, given neoconservatism’s historical foundations and the tenacity of its adherents it seemed important to consider whether this has been the case. Therefore, this thesis set out to answer the question: To what extent have neoconservatives, and neoconservatism more broadly, influenced foreign policy debates during the Obama administration? I argue that neoconservatism has remained not only salient within foreign policy debates, but prominent in these debates, during Obama’s two terms in office. An examination of US foreign policy towards the nuclear crisis in Iran and the Syrian civil war indicates that neoconservatism had a substantive influence on the policy debates and the options considered within them, particularly in Congress. In some instances, neoconservative policy entrepreneurs contributed to legislation. Furthermore, this thesis finds that neoconservatism has been the predominant approach to foreign policy within the Republican Party on the issues of Iran and Syria during the period under review.