In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Acknowledgements: We thank Ms Margaret Fraser, Ms Samantha Flannigan, and Dr Wing Yee Kwong for their expert assistance. The staff at Grampian NHS Pregnancy Counselling Service were essential for collecting fetuses. We thank Professor Geoffrey Hammond and Dr Marc Simard, University of British Colombia for helpful comments on the manuscript. Supported by grants as follows: Scottish Senior Clinical Fellowship (AJD); Chief Scientist Office (Scottish Executive, CZG/1/109 to PAF, & CZG/4/742 (PAF & PJOS); NHS Grampian Endowments 08/02 (PAF, SB & PJOS); the European Community’s Seventh Framework Programme (FP7/2007-2013) under grant agreement no 212885 (PAF & SMR); the Medical Research Council grants MR/L010011/1 (PAF & PJOS) and MR/K018310/1 (AJD). None of the funding bodies played any role in the design, collection, analysis, and interpretation of data, in the writing of the manuscript, nor in the decision to submit the manuscript for publication

Def1 Promotes the Degradation of Pol3 for Polymerase Exchange to Occur During DNA-Damage–Induced Mutagenesis in Saccharomyces cerevisiae

Funding: Wellcome Trust, 070247/Z/03/A. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Cyclical DNA methyltransferase 3a expression is a seasonal and oestrus timer in reproductive tissues

Acknowledgments This work was funded by the University of Aberdeen CLSM grant to TJS. EWJL was funded by a Society for Reproduction and Fertility undergraduate scholarship. TJS conceived the project, designed experiments, analyzed data and wrote the manuscript. EWJL conducted experiments and analyzed the data. CC conducted the immunocytochemistry. ML conducted HEK293 cell culture assays. EMC and ASB provided technical assistance. The authors thank Gerald Lincoln for critical feedback on a previous version of this manuscript.

Cyclical DNA Methyltransferase 3a Expression Is a Seasonal and Estrus Timer in Reproductive Tissues

Acknowledgments This work was funded by the University of Aberdeen CLSM grant to TJS. EWJL was funded by a Society for Reproduction and Fertility undergraduate scholarship. TJS conceived the project, designed experiments, analyzed data and wrote the manuscript. EWJL conducted experiments and analyzed the data. CC conducted the immunocytochemistry. ML conducted HEK293 cell culture assays. EMC and ASB provided technical assistance. The authors thank Gerald Lincoln for critical feedback on a previous version of this manuscript.