Absolute calibration and characterization of the multiband imaging photometer for Spitzer. I. The stellar calibrator sample and the 24 μm calibration

We present the stellar calibrator sample and the conversion from instrumental to physical units for the 24 μm channel of the Multiband Imaging Photometer for Spitzer (MIPS). The primary calibrators are A stars, and the calibration factor based on those stars is 4.54 × 10^-2 MJy sr^–1 (DN/s)^–1, with a nominal uncertainty of 2%. We discuss the data reduction procedures required to attain this accuracy; without these procedures, the calibration factor obtained using the automated pipeline at the Spitzer Science Center is 1.6% ± 0.6% lower. We extend this work to predict 24 μm flux densities for a sample of 238 stars that covers a larger range of flux densities and spectral types. We present a total of 348 measurements of 141 stars at 24 μm. This sample covers a factor of ~460 in 24 μm flux density, from 8.6 mJy up to 4.0 Jy. We show that the calibration is linear over that range with respect to target flux and background level. The calibration is based on observations made using 3 s exposures; a preliminary analysis shows that the calibration factor may be 1% and 2% lower for 10 and 30 s exposures, respectively. We also demonstrate that the calibration is very stable: over the course of the mission, repeated measurements of our routine calibrator, HD 159330, show a rms scatter of only 0.4%. Finally, we show that the point-spread function (PSF) is well measured and allows us to calibrate extended sources accurately; Infrared Astronomy Satellite (IRAS) and MIPS measurements of a sample of nearby galaxies are identical within the uncertainties.

Multi-modal ultrasound imaging for breast cancer detection

This work describes preliminary results of a two-modality imaging system aimed at the early detection of breast cancer. The first technique is based on compounding conventional echographic images taken at regular angular intervals around the imaged breast. The other modality obtains tomographic images of propagation velocity using the same circular geometry. For this study, a low-cost prototype has been built. It is based on a pair of opposed 128-element, 3.2 MHz array transducers that are mechanically moved around tissue mimicking phantoms. Compounded images around 360 degrees provide improved resolution, clutter reduction, artifact suppression and reinforce the visualization of internal structures. However, refraction at the skin interface must be corrected for an accurate image compounding process. This is achieved by estimation of the interface geometry followed by computing the internal ray paths. On the other hand, sound velocity tomographic images from time of flight projections have been also obtained. Two reconstruction methods, Filtered Back Projection (FBP) and 2D Ordered Subset Expectation Maximization (2D OSEM), were used as a first attempt towards tomographic reconstruction. These methods yield useable images in short computational times that can be considered as initial estimates in subsequent more complex methods of ultrasound image reconstruction. These images may be effective to differentiate malignant and benign masses and are very promising for breast cancer screening. (C) 2015 The Authors. Published by Elsevier B.V.