RADIANCE-A planning software for intra-operative radiation therapy

In the last decades accumulated clinical evidence has proven that intra-operative radiation therapy (IORT) is a very valuable technique. In spite of that, planning technology has not evolved since its conception, being outdated in comparison to current state of the art in other radiotherapy techniques and therefore slowing down the adoption of IORT. RADIANCE is an IORT planning system, CE and FDA certified, developed by a consortium of companies, hospitals and universities to overcome such technological backwardness. RADIANCE provides all basic radiotherapy planning tools which are specifically adapted to IORT. These include, but are not limited to image visualization, contouring, dose calculation algorithms-Pencil Beam (PB) and Monte Carlo (MC), DVH calculation and reporting. Other new tools, such as surgical simulation tools have been developed to deal with specific conditions of the technique. Planning with preoperative images (preplanning) has been evaluated and the validity of the system being proven in terms of documentation, treatment preparation, learning as well as improvement of surgeons/radiation oncologists (ROs) communication process. Preliminary studies on Navigation systems envisage benefits on how the specialist to accurately/safely apply the pre-plan into the treatment, updating the plan as needed. Improvements on the usability of this kind of systems and workflow are needed to make them more practical. Preliminary studies on Intraoperative imaging could provide an improved anatomy for the dose computation, comparing it with the previous pre-plan, although not all devices in the market provide good characteristics to do so. DICOM.RT standard, for radiotherapy information exchange, has been updated to cover IORT particularities and enabling the possibility of dose summation with external radiotherapy. The effect of this planning technology on the global risk of the IORT technique has been assessed and documented as part of a failure mode and effect analysis (FMEA). Having these technological innovations and their clinical evaluation (including risk analysis) we consider that RADIANCE is a very valuable tool to the specialist covering the demands from professional societies (AAPM, ICRU, EURATOM) for current radiotherapy procedures.

Nuevas tecnologías y participación política en tiempos de globalización

Lo primero que se encontrará el lector y lectora en este cuadernillo es una breve y esquemática aproximación o contextualización histórica al uso de las redes telemáticas en política (2). Decía Wright Mills que “muchas veces tenemos que estudiar la historia para librarnos de ella”. De esta forma, una vez enmarcados y ubicados nuestros principales protagonistas, podemos olvidarnos (temporalmente) de esa historia que los ha llevado hasta donde ahora estamos. Además, en este trabajo hemos preferido optar por ecamino empírico, aquel que busca y encuentra casos prácticos a cada paso y que iluminan la senda. Muchas teorizaciones yerran sus análisis o profecías por apresurarse a afirmar categóricamente sin mirar fuera. Nosotros hemos optado por observar de cerca y quedarnos con muchos de los procesos que están, actualmente, en marcha. Es por ello que hemos dedicado gran parte de nuestra aportación a describir algunos casos que hemos valorado como relevantes: el tipo de acceso de las organizaciones sociales a las nuevas tecnologías (3.1), las movilizaciones contra la guerra y el papel de Internet en ellas (3.2) y la aparición de un nuevo movimiento social, los hackers (3.3). A continuación introducimos una pequeña encuesta de producción propia (4) que nos permitirá comparar con otros estudios realizados y sacar alguna conclusión tal vez aventurada. Finalmente dedicamos una parte considerable del estudio (5) a eso que se ha venido denominando la antiglobalización (los movimientos de resistencia a la globalización capitalista) y, en concreto, al papel de un recurso telemático nuevo y sumamente interesante, Indymedia (6), que aparece como complemento de los movimientos antes señalados. La intención final no es otra que obtener una radiografía aproximada de qué pasa y qué se mueve por las fibras y los cables de las redes que nos surcan y surcamos.

Simbologías del espacio y del tiempo de la nueva Albania en El Accidente de Ismaíl Kadaré

En el presente trabajo se pretende abordar el estudio de la novela "El accidente", una de las últimas publicadas por el albanés Ismaíl Kadaré

Charged-current inclusive neutrino cross sections in the SuperScaling model

SuperScaling model (SuSA) predictions to neutrino-induced charged-current pi(+) production in the Delta-resonance region are explored under MiniBooNE experimental conditions. The SuSA charged-current pi(+) results are in good agreement with data on neutrino flux-averaged double-differential cross sections. The SuSA model for quasielastic scattering and its extension to the pion production region are used for predictions of charged-current inclusive neutrino-nucleus cross sections. Results are also compared with the T2K experimental data for inclusive scattering.

Global relativistic folding optical potential and the relativistic Green's function model

Optical potentials provide critical input for calculations on a wide variety of nuclear reactions, in particular, for neutrino-nucleus reactions, which are of great interest in the light of the new neutrino oscillation experiments. We present the global relativistic folding optical potential (GRFOP) fits to elastic proton scattering data from C-12 nucleus at energies between 20 and 1040 MeV. We estimate observables, such as the differential cross section, the analyzing power, and the spin rotation parameter, in elastic proton scattering within the relativistic impulse approximation. The new GRFOP potential is employed within the relativistic Green's function model for inclusive quasielastic electron scattering and for (anti) neutrino-nucleus scattering at MiniBooNE kinematics.

Multi-modal ultrasound imaging for breast cancer detection

This work describes preliminary results of a two-modality imaging system aimed at the early detection of breast cancer. The first technique is based on compounding conventional echographic images taken at regular angular intervals around the imaged breast. The other modality obtains tomographic images of propagation velocity using the same circular geometry. For this study, a low-cost prototype has been built. It is based on a pair of opposed 128-element, 3.2 MHz array transducers that are mechanically moved around tissue mimicking phantoms. Compounded images around 360 degrees provide improved resolution, clutter reduction, artifact suppression and reinforce the visualization of internal structures. However, refraction at the skin interface must be corrected for an accurate image compounding process. This is achieved by estimation of the interface geometry followed by computing the internal ray paths. On the other hand, sound velocity tomographic images from time of flight projections have been also obtained. Two reconstruction methods, Filtered Back Projection (FBP) and 2D Ordered Subset Expectation Maximization (2D OSEM), were used as a first attempt towards tomographic reconstruction. These methods yield useable images in short computational times that can be considered as initial estimates in subsequent more complex methods of ultrasound image reconstruction. These images may be effective to differentiate malignant and benign masses and are very promising for breast cancer screening. (C) 2015 The Authors. Published by Elsevier B.V.