2 resultados para universities and colleges
em Chinese Academy of Sciences Institutional Repositories Grid Portal
Resumo:
This book elucidates the methods of molecular gas dynamics or rarefied gas dynamics which treat the problems of gas flows when the discrete molecular effects of the gas prevail under the circumstances of low density, the emphases being stressed on the basis of the methods, the direct simulation Monte Carlo method applied to the simulation of non-equilibrium effects and the frontier subjects related to low speed microscale rarefied gas flows. It provides a solid basis for the study of molecular gas dynamics for senior students and graduates in the aerospace and mechanical engineering departments of universities and colleges. It gives a general acquaintance of modern developments of rarefied gas dynamics in various regimes and leads to the frontier topics of non-equilibrium rarefied gas dynamics and low speed microscale gas dynamics. It will be also of benefit to the scientific and technical researchers engaged in aerospace high altitude aerodynamic force and heating design and in the research on gas flow in MEMS
| [1] Molecular structure and energy states | (21) | ||
| [2] Some basic concepts of kinetic theory | (51) | ||
| [3] Interaction of molecules with solid surface | (131) | ||
| [4] Free molecular flow | (159) | ||
| [5] Continuum models | (191) | ||
| [6] Transitional regime | (231) | ||
| [7] Direct simulation Monte-Carlo (DSMC) method | (275) | ||
| [8] Microscale slow gas flows, information preservation method | (317) | ||
| [App. I] Gas properties | (367) | ||
| [App. II] Some integrals | (369) | ||
| [App. III] Sampling from a prescribed distribution | (375) | ||
| [App. IV] Program of the couette flow | (383) | ||
| Subject Index | (399) | ||
Resumo:
Recent transcription profiling studies have revealed an unexpectedly large proportion of antisense transcripts in eukaryotic genomes. These antisense genes seem to regulate gene expression by interacting with sense genes. Previous studies have focused on the non-coding antisense genes, but the possible regulatory role of the antisense protein is poorly understood. In this study, we found that a protein encoded by the antisense gene ADF1 acts as a transcription suppressor, regulating the expression of sense gene MDF1 in Saccharomyces cerevisiae. Based on the evolutionary, genetic, cytological and biochemical evidence, we show that the protein-coding sense gene MDF1 most likely originated de novo from a previously non-coding sequence and can significantly suppress the mating efficiency of baker's yeast in rich medium by binding MAT alpha 2 and thus promote vegetative growth. These results shed new light on several important issues, including a new sense-antisense interaction mechanism, the de novo origination of a functional gene, and the regulation of yeast mating pathway.
