8 resultados para SAFER
em Chinese Academy of Sciences Institutional Repositories Grid Portal
Resumo:
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Resumo:
SAFER++NESSIE27456SAFER++6SAFER++45SAFER++2\+{250}256
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SAFERSP-,.SAFER,,..
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Three-dimensional discrete element face-to-face contact model with fissure water pressure is established in this paper and the model is used to simulate three-stage process of landslide under fissure water pressure in the opencast mine, according to the actual state of landslide in Panluo iron mine where landslide happened in 1990 and was fathered in 1999. The calculation results show that fissure water pressure on the sliding surface is the main reason causing landslide and the local soft interlayer weakens the stability of slope. If the discrete element method adopts the same assumption as the limit equilibrium method, the results of two methods are in good agreement; while if the assumption is not adopted in the discrete element method, the critical phi numerically calculated is less than the one calculated by use of the limit equilibrium method for the same C. Thus, from an engineering point of view, the result from the discrete element model simulation is safer and has more widely application since the discrete element model takes into account the effect of rock mass structures.
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An experimental study of the properties of hydrodynamic forces upon a marine pipeline is presented in this paper, in the equilibrium scour conditions for various Keulegan-Carpenter numbers and various initial relative gaps between pipeline and the erosive sandy seabed. The tests are conducted in a U-shaped oscillatory water tunnel with a sand box located at the bottom of the test section. According to the experimental results, the maximum horizontal forces on the pipelines with an initial gap to seabed will decrease to some extent due to scouring process. For engineering appliances, it seems safer to estimate wave induced forces on pipelines under the assumption that seabed is plane. However, it should be noticed that great changes would be brought to the frequency properties of lift forces because of the sandy scour beneath the pipeline, which occurs for certain KC numbers.
Resumo:
NESSIE(New European Schemes for SignaturesIntegrityand Encryption)200032000111314NESSIENESSIE1791213NESSIENESSIE7IDEAKhazadMISTY1SAFER++CamelliaRC6SHACALNESSIENEESIENESSIENESSIE
Resumo:
5,0001,500WHO50 µg•L-110 µg•L-1 20~400.2 M KBH420 d•min-1Fe/82.0 mg•g-130~500 nm1,000~2,000 nm As()As()As()pHpHAs()12 h72 hLangmuir As()12.0 mg•g-1pH 6.5 (252) As()2 mg•L-11.0 g•L-1As()75.2%1.5 g•L-1As()99.9%0.1MNaOH12 hPO43-SiO32-As()SO42-CO32-C2O42-Fe2+As()0.1 M NaOH As()pHAs()pH 6.5 (252) As()2 mg•L-11.0 g•L-1 As()99.8%1.996mg•g-1As()As()As()-As()As()As() As() As()As()As()As()
Resumo:
Nonviral vectors are safer than viral systems for gene therapy applications. However, the limited efficacy always prevents their being widely used in clinical practice. Aside from searching new gene nonviral vectors, many researchers focus on finding out new substances to improve the transfection efficiency of existent vectors. In this work, we found a transfection enhancer, nocodazole (NCZ), for dimethyldioctadecylammonium (DODAB, a cationic lipid) bilayer coated gold nanoparticles (AuNPs) mediated gene delivery. It was found that NCZ produces 3-fold transfection enhancement to HEK 293T cells assessed by flow cytometry (FCM). The result was further confirmed by luciferase assay, in which NCZ induced more than 5 times improvement in transfection efficiency after 48 h of transfection. The results from the inductively coupled plasma mass spectrometry (ICP-MS) and FCM showed that NCZ did not affect the internalization of DODAB-AuNPs/DNA complexes. The trafficking of the complexes by transmission electron microscopy (TEM) indicated that the interrupted transportation of the complexes to the lysosomes contributed greatly to the transfection enhancement.
