1 resultado para Learning processes
em Chinese Academy of Sciences Institutional Repositories Grid Portal
Filtro por publicador
- JISC Information Environment Repository (1)
- Repository Napier (2)
- Aberystwyth University Repository - Reino Unido (2)
- Academic Archive On-line (Karlstad University; Sweden) (1)
- Academic Archive On-line (Stockholm University; Sweden) (2)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- Adam Mickiewicz University Repository (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (5)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (3)
- Archive of European Integration (3)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (8)
- Aston University Research Archive (15)
- Biblioteca de Teses e Dissertações da USP (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (1)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (10)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (38)
- Boston University Digital Common (10)
- Brock University, Canada (13)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- Bulgarian Digital Mathematics Library at IMI-BAS (2)
- CaltechTHESIS (2)
- Cambridge University Engineering Department Publications Database (34)
- CentAUR: Central Archive University of Reading - UK (29)
- Central European University - Research Support Scheme (1)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (1)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (6)
- CORA - Cork Open Research Archive - University College Cork - Ireland (4)
- Dalarna University College Electronic Archive (7)
- Deakin Research Online - Australia (118)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (3)
- Digital Archives@Colby (1)
- Digital Commons - Michigan Tech (1)
- Digital Commons @ DU | University of Denver Research (1)
- Digital Commons at Florida International University (5)
- Digital Peer Publishing (9)
- DigitalCommons - The University of Maine Research (1)
- DigitalCommons@The Texas Medical Center (5)
- Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland (3)
- Duke University (1)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (1)
- Escola Superior de Educação de Paula Frassinetti (3)
- Fachlicher Dokumentenserver Paedagogik/Erziehungswissenschaften (3)
- Glasgow Theses Service (1)
- Greenwich Academic Literature Archive - UK (1)
- Helda - Digital Repository of University of Helsinki (13)
- Helvia: Repositorio Institucional de la Universidad de Córdoba (1)
- Indian Institute of Science - Bangalore - Índia (6)
- Instituto Politécnico de Castelo Branco - Portugal (2)
- Instituto Politécnico de Santarém (2)
- Instituto Politécnico do Porto, Portugal (14)
- Instituto Superior de Psicologia Aplicada - Lisboa (1)
- Lume - Repositório Digital da Universidade Federal do Rio Grande do Sul (2)
- Massachusetts Institute of Technology (1)
- Memoria Académica - FaHCE, UNLP - Argentina (13)
- Ministerio de Cultura, Spain (3)
- National Center for Biotechnology Information - NCBI (8)
- Nottingham eTheses (2)
- Open University Netherlands (6)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (1)
- Portal de Revistas Científicas Complutenses - Espanha (6)
- Publishing Network for Geoscientific & Environmental Data (1)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (28)
- Queensland University of Technology - ePrints Archive (158)
- RDBU - Repositório Digital da Biblioteca da Unisinos (2)
- ReCiL - Repositório Científico Lusófona - Grupo Lusófona, Portugal (4)
- Repositório Aberto da Universidade Aberta de Portugal (1)
- Repositorio Académico de la Universidad Nacional de Costa Rica (5)
- Repositório Científico da Universidade de Évora - Portugal (8)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (7)
- Repositório Científico do Instituto Politécnico de Santarém - Portugal (2)
- Repositório digital da Fundação Getúlio Vargas - FGV (23)
- Repositório Institucional da Universidade de Aveiro - Portugal (11)
- Repositório Institucional da Universidade de Brasília (1)
- Repositório Institucional da Universidade Federal do Rio Grande - FURG (1)
- Repositório Institucional da Universidade Tecnológica Federal do Paraná (RIUT) (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (59)
- Research Open Access Repository of the University of East London. (3)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (3)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (1)
- Universidad de Alicante (9)
- Universidad del Rosario, Colombia (6)
- Universidad Politécnica de Madrid (19)
- Universidade de Lisboa - Repositório Aberto (13)
- Universidade dos Açores - Portugal (1)
- Universidade Federal de Uberlândia (1)
- Universidade Federal do Pará (3)
- Universidade Federal do Rio Grande do Norte (UFRN) (17)
- Universidade Metodista de São Paulo (9)
- Universidade Técnica de Lisboa (1)
- Universitat de Girona, Spain (5)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (5)
- Université de Lausanne, Switzerland (2)
- Université de Montréal, Canada (9)
- University of Michigan (1)
- University of Queensland eSpace - Australia (14)
- University of Southampton, United Kingdom (1)
- University of Washington (2)
- WestminsterResearch - UK (2)
- Worcester Research and Publications - Worcester Research and Publications - UK (2)
Resumo:
Rewarding experience after drug use is one of the mechanisms of substance abuse. Previous evidence indicated that rewarding experience was closely related to learning processes. Neuroscience studies have already established multiple-mode learning model. Reference memory system and habit memory are associated with hippocampus and dorsa striatum respectively, which are also involved in the rewarding effect of morphine. However, the relationship between spatial/habit learning and morphine reward property is still unclear. After drug use, with sensitization to rewarding effect, spatial learning is also changed. To study the mechanism of increment of spatial learning would provide new perspective about reward learning. Based on the individual difference between spatial learning and reward learning, the experiments studied relationship between the two leaning abilities and tested the function of dorsal hippocampus and dorsal striatum in morphine-induced CPP. The results were summarized below: 1 In a single-rule learning water maze task, subjects better in spatial learning also excelled in rewarding learning. In a multi-rule learning task, morphine administration was more rewarding to subjects of use place strategy. 2 Treatment potentiating the rewarding effect of morphine also increased place-rule learning, with no significant improvement in habit learning. 3 Intracranial injections into CA1 of hippocampus or dorsal striatum of M1 antagonist, Pirenzepine, could block the establishment of morphine CPP after three days morphine treatment. In contrast, the antagonist of D1 receptor SCH23390 had no blocking effect. Both Pirenzepine and SCH23390 blocked the locomotor-stimulating effect of morphine. In summary, spatial learning stimulated the behavioral expression of morphine’s rewarding effect, in which CA1 of hippocampus was critically involved. On the other side, a pretreatment schedule of morphine, while increased the rewarding effect, improved place-rule learning, indicating that spatial learning might be one chain of sensitization to drug rewards effects