Morphine withdrawal affects both delayed-escape behaviour in Morris water maze and hippocampal NR2A/2B expression ratio

Repeated low-dose morphine treatment facilitates delayed-escape behaviour of hippocampus-dependent Morris water maze and morphine withdrawal influences hippocampal NMDA receptor-dependent synaptic plasticity. Here, we examined whether and how morphine wit

中国拉曼光谱研究十年(1981～1991)

本文介绍了1981～1991年的十年间我国在有机化学、无机化学、生物化学及简正振动分析各领域里拉曼和表面增强拉曼光谱研究的概况。

Effects of starvation on larval growth, survival and metamorphosis of Ivory shell Babylonia formosae habei Altena et al., 1981 (Neogastropoda : Buccinidae)

The impact of starvation on larvae of Ivory shell Babylonia formosae habei was studied in a laboratory experiment. Newly hatched veligers showed considerable tolerance to starvation due to their endogenous yolk material, and time to the point-of-no-return (PNR; the threshold point during starvation after which larvae can longer metamorphose even if food is provided) was calculated to be 104.5 h. However, starvation still affected larval growth, survival, and metamorphosis. Mean shell length of larvae increased 49.77 mum day(-1) for nonstarved, but only 11.13 mum day (-1) for larvae starved for 108 h. After larvae began feeding, their growth rates rapidly recovered to the level of the nonstarved following short periods of starvation (less than 48 h), but were inhibited and unable to ever reach the level of the nonstarved when being starved beyond 48 h. Percent metamorphosis was 53.75% for the nonstarved, but all larvae died before 10 days for those starved for 108 h. Starvation not only affected larval time to reach metamorphosis, but also caused the delay in the time to metamorphosis. For the nonstarved, larvae took only 11.5 days to reach spontaneous metamorphosis, but they took 20 days to reach spontaneous metamorphosis when starved for 96 h, and this duration of delayed metamorphosis reached 8.5 days. Furthermore, the importance of yolk material for maintaining larval survival of B. formosae habei during starvation periods is also discussed. (C) 2004 Elsevier B.V. All rights reserved.

青藏公路与铁路沿途1981年～2001年植被覆盖变化

在青藏公路与铁路沿途区域,利用1981年至2001年的8km分辨率PathfinderNOAA/NDVI数据,基于每个象元变化的年植被峰值计算进行了像元水平的线性趋势分析,并运用地理信息系统(GIS)软件研究了区域植被覆盖的空间分布和动态变化特征.主要结论:①在研究区内,反映植被覆盖的NDVI值在空间上呈现出两端高中间低的态势,依次是农作区和森林区＞高寒草甸＞高寒草原＞荒漠草原;②20年间,研究区植被覆盖程度变化总体趋于稳定,覆盖程度呈减少趋势的区域明显高于增加的区域,植被覆盖程度增减因区域而异;植被覆盖程度增加和显著减少地区主要分布在农作区和高寒草甸区,轻微减少地区主要分布在高寒草原和荒漠草原区;③植被覆盖变化程度在拉萨河谷地、湟水谷地和黄河流域等人类活动比较频繁的区域增减趋势比较明显;而在可可西里地区等人类活动比较少的区域变化轻微.

隔区损毁对大鼠空间认知能力的影响及其在Morris迷宫中搜索策略的比较

Separate groups of rats with bilateral or unilateral lesions in septum were tested for acquisition and retention of the Morris water maze spatial cognitive task. Some of the animals in each lesion group received preoperative training in the task. Other animals in each group received no preoperative training. The results indicate that although both lesions lead to a spatial cognitive impairment in both the acquisition and retention of the task, the animals with bilateral lesions were more severely impaired than were the animals with unilateral, as indicated by quantitative measure. Searching strategies were used as an index to eximine the qualitative difference in the animals swim be havior, we found that the unilateral damaged animals still tend to use "mapping" strategies to solve the task as in the case of control groups but the accuracy is lower. The searching strategies used by the bilateral damaged animals showed complex patterns. The acquisition group with bilateral tend to use random and paratic strategies, however, the retention group with bilateral had a tendacy to use paratic and taxic strategies. The difference between searching strategies and its dynamic, change possibly suggest that other cognitive processing systems play an role in the processing of information about the task.