钢丝绳结构及工艺集成设计系统

针对钢丝绳实际生产需要,提出基于钢丝绳结构理论设计基础的结构与工艺集成设计系统框架,建立钢丝绳结构设计、性能分析及间隙计算的理论模型,并利用相关数据进行理论值与实际值分析,完成钢丝绳性能参数的敏感性分析模型和理论修正模型,为钢丝绳结构设计与工艺设计的并行处理提供了理论上的指导,最终实现钢丝绳的智能设计与制造

Application of uniform design and genetic algorithm in optimization of reversed-phase chromatographic separation

An optimization method based on uniform design in conjunction with genetic algorithm is described. According to the proposed method, the uniform design technique was applied to the design of starting experiments, which can reduce the number of experiments compared with traditional simultaneous methods, such as simplex. And genetic algorithm was used in optimization procedure, which can improve the rapidity of optimal procedure. The hierarchical chromatographic response function was modified to evaluate the separation equality of a chromatogram. An iterative procedure was adopted to search for the optimal condition to improve the accuracy of predicted retention and the quality of the chromatogram. The optimization procedure was tested in optimization of the chromatographic separation of 11 alkaloids in reversed-phase ion pair chromatography and satisfactory optimal result was obtained. (C) 2003 Elsevier B.V. All rights reserved.