经皮制剂高效筛选实验自动化系统基于MSC1210和ROLAND DXY-880A绘图仪设计

介绍了经皮制剂高效筛选实验的原理和方法。介绍了MSC1210的结构和性能,主要讨论了其在高精度数据采集中的应用。分析基于MSC1210和ROLAND DXY-880A绘图仪的经皮制剂高效筛选实验自动化系统的硬件结构和软件设计,详细讨论了软件部分的设计和实现。

第17届国际气体放电会议(ICPIG-17)

<正> Ⅰ.概况 国际气体放电会议(ICPIG)每两年举行一次,主要交流在气体放电领域中有关的研究和发展情况。ICPIG-17由匈牙利Roland Etvs物理学会和物理中心研究所组织,匈牙利科学院赞助,在布达佩斯技术大学举行。会期1985年7月8—12日。到会代表360人,其中我国1人。邀请报告共31篇,其中11篇在大会上宣读。张贴论文共394篇。

T-Muurolol Sesquiterpenes from the Marine Streptomyces sp M491 and Revision of the Configuration of Previously Reported Amorphanes

Two new sesquiterpenes, 15-hydroxy-T-muurolol (3d) and 11,15-dihydroxy-T-muurolol (3e), along with the plant cadinenes T-muurolol (3f) and 3 alpha-hydroxy-T-muurolol (3g), were isolated from the marine-derived Streptomyces sp. M491. Their absolute configuration was established via NMR spectroscopy and X-ray crystallography of 3-oxo-T-muurolol (3a), which was reisolated from this strain. In addition, the absolute configuration of further sesquiterpenes previously reported from this strain was revised. These products were tested for their cytotoxicity against 37 human tumor cell lines using the MTT method. Only 3d was cytotoxic against a range of human tumor cell lines with a mean IC50 of 6.7 mu g/mL.