36 resultados para BMP-K2
em Chinese Academy of Sciences Institutional Repositories Grid Portal
Resumo:
Unicode标准中的非BMP平面字符多用于古籍研究或者少数民族语言文字,由于这些字符的使用面特别窄,多数软件系统包括办公软件都不支持对这些字符的处理。本文以开源办公套件OpenOffice.org为基础,分析了它对非BMP平面支持的现状,然后着重探讨了实现对非BMP平面字符的全面支持所需要解决的一系列问题,并分别给出了合理的改进方案,最后以CJK和藏文为例展示了改进后的效果。
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The complex, K2.5Na2NH4[Mo2O2S2(cit)(2)]. 5H(2)O (1), was obtained by crystallization from a solution of (NH4)(2)MoS4, potassium citrate (K(3)cit) and hydroxyl sodium in methanol and water under an atmosphere of pure nitrogen at ambient temperature. The crystals are triclinic, space group
, a = 7.376 (3)Angstrom, b = 14.620 (2) Angstrom, c = 14.661 (1) Angstrom, alpha = 71.10 (1)degrees, beta = 81.77 (1)degrees, gamma = 78.27(2)degrees, R = 0.0584 for 2545 observed (I > 2 sigma (I)) reflections. Single crystal structure analysis reveals that citrate ligand coordinated to molybdenum atom through two carboxylato oxygens and one deprotonated hydroxyl oxygen together with two bridging sulfur atoms and a terminal oxygen atom completes distorted coordination octahedron around each molybdenum atom. Principal dimensions are: Mo = O-t, 1.707 Angstrom (av); Mo-S-b, 2.341 Angstrom (av); Mo-O-(hydroxyl), 2.021 Angstrom (av); Mo-O(alpha-carboxyl), 2.1290 Angstrom (av) and Mo-O(beta-carboxyl), 2.268(av) Angstrom. IR spectrum is in agreement with the structure.
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In this paper, we present an exact higher-order asymptotic analysis on the near-crack-tip fields in elastic-plastic materials under plane strain, Mode I. A four- or five-term asymptotic series of the solutions is derived. It is found that when 1.6 < n less-than-or-equal-to 2.8 (here, n is the hardening exponent), the elastic effect enters the third-order stress field; but when 2.8< n less-than-or-equal-to 3.7 this effect turns to enter the fourth-order field, with the fifth-order field independent. Moreover, if n>3.7, the elasticity only affects the fields whose order is higher than 4. In this case, the fourth-order field remains independent. Our investigation also shows that as long as n is larger than 1.6, the third-order field is always not independent, whose amplitude coefficient K3 depends either on K1 or on both K1 and K2 (K1 and K2 arc the amplitude coefficients of the first- and second-order fields, respectively). Firmly, good agreement is found between our results and O'Dowd and Shih's numerical ones[8] by comparison.
Resumo:
A HIGHER-ORDER asymptotic analysis of a stationary crack in an elastic power-law hardening material has been carried out for plane strain, Mode 1. The extent to which elasticity affects the near-tip fields is determined by the strain hardening exponent n. Five terms in the asymptotic series for the stresses have been derived for n = 3. However, only three amplitudes can be independently prescribed. These are K1, K2 and K5 corresponding to amplitudes of the first-, second- and fifth-order terms. Four terms in the asymptotic series have been obtained for n = 5, 7 and 10; in these cases, the independent amplitudes are K1, K2 and K4. It is found that appropriate choices of K2 and K4 can reproduce near-tip fields representative of a broad range of crack tip constraints in moderate and low hardening materials. Indeed, fields characterized by distinctly different stress triaxiality levels (established by finite element analysis) have been matched by the asymptotic series. The zone of dominance of the asymptotic series extends over distances of about 10 crack openings ahead of the crack tip encompassing length scales that are microstructurally significant. Furthermore, the higher-order terms collectively describe a spatially uniform hydrostatic stress field (of adjustable magnitude) ahead of the crack. Our results lend support to a suggestion that J and a measure of near-tip stress triaxiality can describe the full range of near-tip states.
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In this paper, the governing equations and the analytical method of the secondorder asymptotic field for the plane-straln crack problems of mode I have been presented. The numerical calculation has been carried out. The amplitude coefficients k2 of the second term of the asymptotic field have been determined after comparing the present results with some fine results of the finite element calculation. The variation of coefficients k2 with changes of specimen geometry and developments of plastic zone have been analysed. It is shown that the second term of the asymptotic field has significant influence on the near-crack-tip field. Therefore, we may reasonably argue that both the J-integral and the coefficient k2 can beeome two characterizing parameters for crack initiation.
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波浪作用下海床的稳定性与液化分析是海底管线、防波堤和海洋平台设计中必须仔细考虑的问题。本文推荐了一个循环荷载作用下土体的弹塑性实用本构模型,并给出了一种粉土的模型参数。该模型直接根据初始应力状态和循环应力的大小与作用时间计算土体的塑性应变增量,在有限元计算中不需要引入弹塑性矩阵。采用Biot理论和有限单元法,对海床有效应力的变化过程分析表明,波腹点下海床存在较大的液化可能性。波浪作用对海床存在一定的压密作用。
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利用高重频YAG激光作用在固体表面所产生的等离子体使工件和电极之间在大气环境中并且电压远低于击穿闭值的条件下产生可控定向放电。实验结果显示,放电坑基本上呈火山坑形,既有单坑结构,也有多坑结构,其形貌受到放电波形、电源极性、放电介质等因素的影响。放电坑表面形貌的规律是:①除了涂油时的阳极放电坑是单坑结构以外,其他条件下的放电坑都是复合多坑结构;②单坑结构呈火山坑形,坑底为圆弧形,熔凝物堆积在坑的边缘,而多坑结构则是一个大的放电坑中有多个凸起的尖峰,这种结构有利于毛化加工。研究表明,对于碳钢、铸铁、黄铜三种材料,放电坑直径d与电源参数的关系可以表示成:d∝Iαp(对于三角波),或d∝Υβ(对于矩形波)。α的范围在0.40~0.71,β的范围在0.23~0.47。在工件表面涂油,有利于提高放电的能量密度,使放电坑变深。介质的密度和粘性系数可作为控制放电通道扩展的有效因素。放电能量一定时,有固态相变材料的相变区深度的变化遵从以下规律:①放电波形和电源极性一定时,涂油时的深度>大气时的深度;②极性和介质一定时,矩形波时的深度≥三角波时的深度;③介质和波形一定时,阳极时的深度≥阴极时的深度。与一般的研究电极损耗即放电前后电极的质量差所不同的是,认为在激光诱导放电毛化技术中,对工件电极应该研究放电的侵蚀作用,即实验上可观测到的能量作用的范围所对应的体积V,它不仅包括脱落下来的那部分物质,也包括发生了组织变化的那部分物质。对于有固态相变的材料,V通常就是相变区边界所对应的球冠体积;对于无固态相变的材料,V通常是放电坑的体积。通过量纲分析,揭示出V是一个多元函数。当电极材料和放电介质一定时,对于电流峰值一定的矩形波放电,v主要取决于脉冲宽度γ,其函数关系为:V=K1·Υ1.41~1.45;对于脉冲宽度一定的三角波放电,V主要取决于电流峰值IP,V=K2·I1.30~2.15P,K1、K2为与材料和放电介质有关的常量。在比较分析了脉冲激光束与激光诱导放电在功率密度、作用时间和坑的深度等方面对材料的影响之后,认为:高重频激光束适合于对材料表面进行薄层熔凝和毛化,低重频长脉冲激光束适合于对材料进行表面改性处理,而激光诱导放电具有对材料表面进行造型强化和组织强化的双重作用。设计了一种转动式圆盘电极,延长了工具电极的连续工作时间。
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采用分阶段诱导方法模拟肝细胞体内发育,建立体外诱导猕猴胚胎干细胞(rhesus monkey embryonic stem cells,rESCs)分化为成熟肝细胞的体系,对研究以ES细胞为基础的临床替代治疗人类晚期肝脏疾病具有重要的意义.将rESCs团块在含有10%FBS的DMEM培养基中悬浮培养11d,形成含有早期内胚层细胞的拟胚体(embryonic bodies,EB)并开始表达早期肝细胞的部分基因或蛋白,将11日龄EB接种至包被有ECM的组织培养皿,分阶段加入aFGF、BMP-4及OSM.经aFGF和BMP-4诱导7~10d后,分化细胞形态变为具有双核的多角形细胞,表达早期和中期肝细胞特异性的蛋白(AFP、ALB及CK18)和基因(AFP、ALB、APOH,G-6-P及TAT),并具有储存糖原的功能.撤除aFGF和BMP-4,添加OSM继续诱导7~10 d,分化的细胞表达成熟肝细胞所特有基因CYP1B1和ADH1C,并具有摄取靛青绿的能力.
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使用分子生物学的方法对亚科鱼类的单系性进行了探讨。通过PCR方法 ,获得了 13种鲤科鱼类S7核糖体蛋白基因第 1内含子序列 ,其中包括 6种亚科鱼类。使用MEGA软件中的Neighbor Joining法和Most Parsimony法分别构建分支系统图。研究结果显示目前所确认的亚科鱼类实际上没有形成单系类群。其中属、波鱼属和低线属位于系统树基部 ,显示出原始性。而由细鲫属、马口鱼属和属构成的类群相对于亚科中的原始种类起源较晚 ,可能和较晚起源的东亚鲤科类群之间有更为密切的关系。
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介绍多年来对鲸类动物在人工饲养条件下繁殖问题的研究成果 ,包括 :雌雄性生殖器官的组织解剖 ,饲养和采精训练 ,人工饲养条件下的繁殖 ,孕豚护理 ,分娩和幼豚饲养。为推动我国鲸类动物的人工繁殖提供科学资料。
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以 GPS为辅助 ,在保安湖主体湖和桥墩湖进行沉水植物调查。将野外调查数据构建 GIS数据库 ,基于 GIS软件平台 ,运用 Kringing插值法对保安湖沉水植物分布进行模拟。模拟结果清楚地显示出调查时保安湖沉水植物及 4优势种 (金鱼藻 Ceratophyllum demersum L.、穗状狐尾藻 Myriophyllum spicatum L .、微齿眼子菜 Potamogeton maackianus A.Benn.及苦草 Vallisneria spiralis L.)分别在湖中的分布情况。统
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本文介绍了鱼类耳石微结构图像识别系统的工作原理和应用实例 ,该系统实现了对鱼类的耳石日轮的自动识别计数和测量日轮宽度 ,并将分析结果自动保存为Excel可识别格式的数据文件。用草鱼微耳石对该系统进行测试的结果表明 ,在随机抽取的 30个样本中 ,有 2 8个样本日轮自动识别的正确率为 1 0 0 % ,其余 2个样本经过手工修改后也能达到对日轮的完全识别。此外 ,采用 768× 5 82像素的BMP格式数字图像测量日轮宽度 ,计算机的分辨率比显微镜提高了约 1 3倍。该系统还可应用于鱼类的鳞片、胸鳍棘和脊
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应用地高辛标记的对虾白斑杆状病毒 (whitespotsyndromebaculovirus,WSSV)核酸探针 ,与人工感染后不同时间采集的对虾组织样品进行原位杂交 ,以动态研究病毒从侵染至对虾发病死亡的过程。将典型感染WSSV的病虾组织投喂健康对虾 ,结果显示 :WSSV首先通过侵染消化道上皮进入虾体内增殖 ,此后随着细胞裂解、病毒粒子释放 ,游离的病毒粒子伴随血淋巴循环进而侵染其它靶组织 ,直至对虾发病死亡。
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中国科学院资助项目 (K2 9511- 131- 111) ; 农业部重点科研项目 (渔 95 -B - 96 - 0 6 - 0 3) ; 湖北省自然科学基金资助 项目
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Insect PGRPs can function as bacterial recognition molecules triggering proteolytic and/or signal transduction pathways, with the resultant production of antimicrobial peptides. To explore if zebrafish peptidoglycan recognition protein SC (zfPGRP-SC) has such effects, RNA interference (siRNA) and high-density oligonucleotide microarray analysis were used to identify differentially expressed genes regulated by zfPGRP-SC. The mRNA levels for a set of genes involved in Toll-like receptor signaling pathway, such as TLRs, SARM, MyD88, TRAF6 and nuclear factor (NF)-kappa B2 (p100/p52), were examined by quantitative RT-PCR (QT-PCR). The results from the arrays and QT-PCR showed that the expression of 133 genes was involved in signal transduction pathways, which included Toll-like receptor signaling, Wnt signaling, BMP signaling, insulin receptor signaling, TGF-beta signaling, GPCR signaling, small GTPase signaling, second-messenger-mediated signaling, MAPK signaling, JAK/STAT signaling, apoptosis and anti-apoptosis signaling and other signaling cascades. These signaling pathways may connect with each other to form a complex network to regulate not just immune responses but also other processes such as development and apoptosis. When transiently over-expressed in HEK293T cells, zfPGRP-SC inhibited NF-kappa B activity with and without lipopolysacharide (LPS) stimulation. (C) 2008 Elsevier Ltd. All rights reserved.