Association of pro staglandin-endoperoxide synthase 2 (PTGS2) polymorphisms and Alzheimer's disease in Chinese

Cyclooxygenase-2 (COX-2, encoded by the gene prostaglandin-endoperoxide synthase 2, PTGS2) is a key enzyme in the conversion of arachidonic acid to prostaglandins. The prostaglandins produced by COX-2 are involved in inflammation and pain response in diff

Polymorphisms of the estrogen receptor alpha (ESR1) gene and the risk of Alzheimer's disease in a southern Chinese community

Background: Alzheimer's disease (AD) is a neurodegenerative disease with a higher prevalence in women. Expression of estrogen receptor 1 (ESR1) gene has been identified throughout the brain. Owing to the putative neuroprotective effects of estrogen, estro

Rapid label-free detection of metal-induced Alzheimer's amyloid beta peptide aggregation by electrochemical method

Amyloid beta peptide plays a critical role in the pathogenesis of Alzheimer's disease (AD). Metal ions are highly enriched in cerebral amyloid deposits in AD and are proposed to be able to mediate A beta conformation. Therefore, a rapid, low-cost, and sensitive detection of metal-induced A beta aggregation and their relation to AD is clearly needed for the clinical diagnosis and treatment. In this report, we study metal-induced A beta aggregation by a rapid, label-free electrochemical method and monitor both the aggregation kinetics and the morphology in the absence or presence of Zn (II) and Cu (II).

STUDIES ON MORPHOLOGY OF SOLUTION-CAST FILMS OF IPP/APP BLENDS

Morphologies of solution-cast films of iPP/aPP blends have been studied by means of electron microscopy and X-ray scattering techniques. Microscopic observation showed that solution-cast film of iPP consists of two kinds of structural regions, cross-hatched and lath-liked structures. The addition of small amount of aPP (less than or equal to 30%) into iPP did not change iPP's characteristic crystallization behavior. It is noticed that when the content of aPP in its blend was over 80%, iPP formed a very loosely woven-like network composed of very long lamellae with wide-angle lamellar branchings. The X-ray data showed that aPP did not cocrystallize with iPP.

iPP／aPP共混物溶液浇铸薄膜的形态结构研究

用透射电子显微镜和Ｘ射线衍射等方法研究了等规立构聚丙烯（ｉＰＰ）和无规立构聚丙烯（ａＰＰ）共混物溶液浇铸膜的形态结构，结果表明，ａＰＰ的加入对ｉＰＰ的形态结构有很大的影响。

iPP/aPP共混物薄膜的形态结构研究

聚烯烃共混物中,最常见的和已商品化的是 iPP 与三元乙丙橡胶(EPDM)的共混物。人们一直用 EPDM 或乙丙无规共聚物(EPR)作为增韧剂加入到 iPP 中以提高其冲击强度。实验证明,橡胶的加入会导致 iPP 形态结构的变化。aPP 是一种非晶聚合物,它有类似像胶的性能,据报道,aPP 与 iPP 在熔体是相容的,aPP 的加入对 iPP 形态结构有很大影响。本文用 TEM 和 X-射线衍射等方法研究了 iPP/aPP 共混物薄膜的形态结构。

iPP／aPP共混物薄膜的形态结构研究

ｉＰＰ／ａＰＰ共混物薄膜的形态结构研究陈晔，杨德才（中国科学院长春应用化学研究所高分子物理开放实验室，长春１３００２２）聚烯烃共混物中，最常见的和已商品化的是ｉＰＰ与三元乙丙橡胶（ＥＰＤＭ）的共混物。人们一直用ＥＰＤＭ或乙丙无规共聚物（ＥＰＲ）作为增...