47 resultados para 1068
em Chinese Academy of Sciences Institutional Repositories Grid Portal
Resumo:
经典广义自洽模型的最大不足是需要确定相材料的位移及应变场,这一过程十分繁杂,而且最后得到的有交剪切模量无法显式表达难以应用,该文摈弃这一经典做法,而从广义自洽模型的应变等价条件出发,在夹杂应变均匀的近似假定下,将Hill界面条件应用于整个二相体内,从而得到一种可以预报涂层夹杂体复合材料有效模量的广义自洽Mori-Tanaka模型,与已有的实验及理论的比较表明,该模型准确可靠,而且有效体积和剪切模量…
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在柱坐标系下,通过奇异摄动理论的多尺度展开法求解势流方程,研究了垂直强迫激励圆柱形容器中的单一模式水表面驻波模式.假设流体是无粘、不可压且运动是无旋的,在忽略了表面张力的影响下,用两变量时间展开法得到一个具有立方项以及底部驱动项影响的非线性振幅方程.对上述方程进行了数值计算,计算的结果显示了在不同驱动振幅和驱动频率下,会激发不同自由水表面驻波模式,从等高线的图像来看,和以往的实验结果相当吻合.
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改进了现有的基于径向双折射晶体的横向超分辨滤波器.通过调整偏振器的偏振方向和晶体光轴之间的夹角,改进的滤波器可以实现更广的超分辨可调范围,并且在相同的条件下,相对于现有的连续振幅型超分辨光瞳滤波器,超分辨性能和焦深都有较大提高.改进的超分辨滤波器,为实际应用提供了更多方便.
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目的:研究槐花提取化合物K3的体外抗HIV-1活性,并对其抗HIV-1机制进行初步探讨.方法:采用MTT比色法检测化合物对各种细胞的毒性.用合胞体形成计数法,p24抗原捕获ELISA法及RT-PCR等多种方法研究化合物体外抗HIV-1活性.结论:槐花提取化合物K3体外有较好的抗HIV-1活性,能够抑制病毒实验株(HIV-1ⅢB,耐药株(HIV-1 74v)和临床分离株(HIV-1KM018)等多种病毒株的复制,且其作用机制是多靶点的,不仅可以抑制病毒的进入,还可以抑制HIV-1逆转录酶活性.
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嗅觉是动物至关重要的感官,而嗅觉受体基因则构成了嗅觉的基础.嗅觉受体跟环境气味分子的相互作用被认为是嗅觉过程发生的第一步.气味分子结合被认为发生在由跨膜区形成的一个口袋结构中,而直接结合位点叫做绑定位点.以往的研究显示,绑定位点可能因为功能分化而受到正向选择.本研究对青鳉和三刺鱼的基因组中鉴定了OR基因,并对这些序列进行了进化分析.通过不同跨膜区与整个编码区的选择压力的比较,发现跨膜区4,5,6有较高的平均Ka/Ks值,这可能在某种程度上由正向选择所致.同时发现,许多受正向选择的位点主要分布在跨膜区.通过
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<正>中国水污染现状当前的中国,水污染和水体富营养化已成为严重的环境问题。经济合作组织(OECD)2007年7月17日的报告称,中国主要城市水质近一半不完全符合饮用水源水质标准。污染源当中,最主要的是粪便排污,其次为工业和农业化学污染;
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线虫是多样性仅次于昆虫的一个动物类群.秀丽隐杆线虫已经成为现代发育生物学、遗传学和基因组学研究的重要模式材料.然而线虫的系统位置及其系统发育关系一直争议颇多.近年来,分子系统发育研究使经典线虫系统学面临巨大的挑战,不仅提出了线虫属于蜕皮动物以及线虫五大分支系统等新观点,同时为动物分子鉴定和系统发育多样性研究提供了新思路.
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The 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) isoenzymes play a key role in cellular steroid hormone synthesis. Here, a 3 beta-HSD gene homolog,was cloned from Rana grylio virus (RGV), a member of family Iridoviridae. RGV 3 beta-HSD gene has 1068 bp, encoding a 355 aa predicted protein. Transcription analyses showed that RGV 3 beta-HSD gene was transcribed immediate-early during infection from an initiation site 19 nucleotides upstream of the translation start site. Confocal microscopy revealed that the 3 beta-HSD-EGFP fusion protein was exclusively colocalized with the mitochondria marker (pDsRed2-Mito) in EPC cells. Upon morphological observation and MTT assay, it was revealed that overexpression of RGV 3 beta-HSD in EPC cells could apparently suppress RGV-induced cytopathic effect (CPE). The present studies indicate that the RGV immediate-early 3 beta-HSD gene encodes a mitochondria-localized protein, which has a novel role in suppressing virus-induced CPE. All these suggest that RGV 3 beta-HSD might be a protein involved in host-virus interaction. @ 2006 Elsevier Inc. All rights reserved.
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The mode characteristics of a three-dimensional (3D) microdisk with a vertical refractive index distribution of n(2)/3.4/n(2) are investigated by the S-matrix method and 3D finite-difference time-domain (FDTD) technique. For the microdisk with a thickness of 0.2 mu m. and a radius of 1 mu m, the mode wavelengths and quality factors for the HE7,1 mode obtained by 3D FDTD simulation and the S-matrix method are in good agreement as n(2) increases from 1.0 to 2.6. But the Q factor obtained by the 3D FDTD rapidly decreases from 1.12 X 10(4) to 379 as n2 increases from 2.65 to 2.8 owing to the vertical radiation losses, which cannot be predicted by the proposed S-matrix method. The comparisons also show that quality factors obtained from the analytical solution of two-dimensional microdisks under the effective index approximation are five to seven times smaller than those of the 3D FDTD as n(2) = 1 and R = 1 mu m. (c) 2006 Optical Society of America.
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Red shifts of emission wavelength of self-organized In(Cla)As/GaAs quantum dots (QDs) covered by 3 nm thick InxGa1-xAs layer with three different In mole fractions (x = 0.1, 0.2 and 0.3, respectively) have been observed. Transmission electron microscopy images demonstrate that the stress along growth direction in the InAs dots was reduced due to introducing the InxGa1-xAs (x = 0.1, 0.2 and 0.3) covering layer instead of GaAs layer. Atomic force microscopy pictures show a smoother surface of InAs islands covered by an In0.2Ga0.8As layer. It is explained by the calculations that the redshifts of the photoluminescence (PL) spectra from the QDs covered by the InxGa1-xAs (x greater than or equal to 0.1) layers were mainly due to the reducing of the strain other than the InAs/GaAs intermixing in the InAs QDs. The temperature dependent PL spectra further confirm that the InGaAs covering layer can effectively suppress the temperature sensitivity of PL emissions. 1.3 mum emission wavelength with a very narrow linewidth of 19.2 mcV at room temperature has been obtained successfully from In,In0.5Ga0.5As/GaAs self-assembled QDs covered by a 3-nm In0.2Ga0.2As strain reducing layer. (C) 2001 Elsevier Science B.V. All rights reserved.