Multiphase Flow Measurement in the Offshore Oil Industry

In recent years, considerable research has been conducted into the development of a three-phase flowmeter suitable for use in an offshore environment, and oil/gas/water three-phase metering becomes an important aspect in multiphase flow measurement. This paper discusses the importance of three-phase flow measurement in offshore oil industry, describes the current development in this area, and points out the principal strategies which may be used to meter three-phase flow.

低渗油田“层内爆炸”增产技术的小尺度模拟实验研究

本文是关于低渗油田增产技术的室内模拟实验研究的论文。我们对井内爆炸采油、核爆采油和高能气体压裂进行全面调研以后，吸取了井内爆炸采油的教训，借鉴了高能气体压裂的成功经验，提出了低渗油田“层内爆炸”增产技术。该技术是利用水力压裂技术的现有设备，将适当的炸药压入岩石裂缝，再用适当的方法起爆，从而在岩石裂缝周围产生大量裂缝，在不会对储层产生不利影响也不会毁坏井筒的前提下，达到提高采取收率并增产油气的目的。首先，建立了圆管点火实验装置、小尺度模拟实验装置和平板点火实验装置；然后利用实验装置进行了“层内爆炸”用特种火药和特种炸药配方的探索。通过实验我们至少找到了一种“层内爆炸”用药品的配方，并且在小尺度模拟实验装置中实现了“层内爆炸”基本过程的模拟实验，从而证实“层内爆炸”思路正确，原理上可行。接着，建立了爆燃推进的模型，并在恒稳推进和不可压缩简化条件下得到几组算例，这些解在物理上是合理的。通过计算我们得知爆燃恒温推进的条件是苛刻的，需要多个参数的匹配。通过本人硕士论文的工作，证实了低渗油田“层内爆炸”增产技术在原理上的可行性。但因为“层内爆炸”过程中牵涉到多个特征尺度，因此并不能从小尺度向大尺度简单地推广，下一步工作是建立中大尺度模拟实验装置，考察在中大尺度条件下“层内爆炸”的可行性，为现场实际应用作充分的实验准备。

Nonlinear Fluid Damping In Structure-Wake Oscillators In Modeling Vortex-Induced Vibrations

A Nonlinear Fluid Damping (NFD) in the form of the square-velocity is applied in the response analysis of Vortex-induced Vibrations (VIV). Its nonlinear hydrodynamic effects oil the coupled wake and structure oscillators are investigated. A comparison between the coupled systems with the linear and nonlinear fluid dampings and experiments shows that the NFD model can well describe response characteristics, such as the amplification of body displacement at lock-in and frequency lock-ill, both at high and low mass ratios. Particularly, the predicted peak amplitude of the body in the Griffin plot is ill good agreement with experimental data and empirical equation, indicating the significant effect of the NFD on the structure motion.

Simulated pathogenic conformational switch regions matched well with the biochemical findings

Pathogenic conformational conversion is a general causation of many disease, such as transmissible spon- giform encephalopathy (TSE) caused by misfolding of prion, sickle cell anemia, and etc. In such structural changes, misfolding occurs in regions important for the stability of native structure firstly. This destabi- lizes the normal conformation and leads to subsequent errors in folding pathway. Sites involved in the first stage can be deemed switch regions of the protein, and are vital for conformational conversion. Namely it could be a switch of disease at residue level. Here we report an algorithm that can identify such sites computationally with an accuracy of 93%, by calculating the probability of the native structure of a short segment jumping to a mistake one. Knowledge of such switch sites could be used to target clinical therapy, study physiological and pathologic mechanism of protein, and etc.

Splitting the fast and slow motions in molecular dynamics simulations based on the change of cold potential well bottom

Abstract. The atomic motion is coupled by the fast and slow components due to the high frequency vibration of atoms and the low frequency deformation of atomic lattice, respectively. A two-step approximate method was presented to determine the atomic slow motion. The first step is based on the change of the location of the cold potential well bottom and the second step is based on the average of the appropriate slow velocities of the surrounding atoms. The simple tensions of one-dimensional atoms and two-dimensional atoms were performed with the full molecular dynamics simulations. The conjugate gradient method was employed to determine the corresponding location of cold potential well bottom. Results show that our two-step approximate method is appropriate to determine the atomic slow motion under the low strain rate loading. This splitting method may be helpful to develop more efficient molecular modeling methods and simulations pertinent to realistic loading conditions of materials.