226 resultados para nitrocefin, HEK 293, HEK 293T, biopharmaceuticals
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本文通过自相关分析探讨在“Maunder极小期”期间太阳活动是否仍然存在11年活动周期.利用Eddy根据欧洲望远镜在“Maunder极小期”时观测的太阳黑子记录所作的相对黑子数年平均值进行了自相关分析,也与中国地方志在“Maunder极小期”时的有关黑子记录一起进行了同样的自相关分析.在作自相关分析时采用几种不同的方法进行比较,结果发现,11年活动周期性的存在与否与所选用的统计方法有关,因此不能绝对地说在“Maunder极小期”时太阳活动完全停止了,或者说在“Maunder极小期”时仍然存在着11年周期的活动性质.
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<正> 由于同位素分离日益增长的需要,提高单极分离系数和产量成为十分重要的问题.机械离心机可以使两种不同气体或液体高速旋转,达到使其分离的目的.但因结构强度限制和存在机械振动,继续提高分离系数有一定困难.能否使用电磁场力来推动两种同位素气体产生更高的转速,达到分离的目的呢?六十年代开始探索其可能性.Gross等人利
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从溶液中聚集体的角度研究了溶液的热历史改变生长出的蛋白质晶体的数目和尺寸的内在原因.将在281和309 K下保存1 d的两组溶菌酶溶液按不同比例混合,加入沉淀剂生长晶体.随着高温溶液的比例增加,生长出的晶体数目减少,同时溶液中生长基元的尺寸增大.在5周内,采用动态光散射对281,293和309K三种温度下保存的溶菌酶溶液中聚集体的变化情况进行监测,发现溶液中均存在大小不同的两部分聚集体,称之为小聚集体与多聚体.前者的尺寸基本不随保存时间而变化,而后者尺寸随保存时间增加而减小,减小的速度与保存温度有关.多聚体的尺寸经过5周后和小聚集体基本相同.研究结果表明,处于无序聚集阶段的溶液的均一化程度和成核阶段生长基元的尺寸受到了溶液热历史的影响,并最终对晶体的数目产生影响.
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Table of Contents
1 | Introduction | 1 |
1.1 | What is an Adiabatic Shear Band? | 1 |
1.2 | The Importance of Adiabatic Shear Bands | 6 |
1.3 | Where Adiabatic Shear Bands Occur | 10 |
1.4 | Historical Aspects of Shear Bands | 11 |
1.5 | Adiabatic Shear Bands and Fracture Maps | 14 |
1.6 | Scope of the Book | 20 |
2 | Characteristic Aspects of Adiabatic Shear Bands | 24 |
2.1 | General Features | 24 |
2.2 | Deformed Bands | 27 |
2.3 | Transformed Bands | 28 |
2.4 | Variables Relevant to Adiabatic Shear Banding | 35 |
2.5 | Adiabatic Shear Bands in Non-Metals | 44 |
3 | Fracture and Damage Related to Adiabatic Shear Bands | 54 |
3.1 | Adiabatic Shear Band Induced Fracture | 54 |
3.2 | Microscopic Damage in Adiabatic Shear Bands | 57 |
3.3 | Metallurgical Implications | 69 |
3.4 | Effects of Stress State | 73 |
4 | Testing Methods | 76 |
4.1 | General Requirements and Remarks | 76 |
4.2 | Dynamic Torsion Tests | 80 |
4.3 | Dynamic Compression Tests | 91 |
4.4 | Contained Cylinder Tests | 95 |
4.5 | Transient Measurements | 98 |
5 | Constitutive Equations | 104 |
5.1 | Effect of Strain Rate on Stress-Strain Behaviour | 104 |
5.2 | Strain-Rate History Effects | 110 |
5.3 | Effect of Temperature on Stress-Strain Behaviour | 114 |
5.4 | Constitutive Equations for Non-Metals | 124 |
6 | Occurrence of Adiabatic Shear Bands | 125 |
6.1 | Empirical Criteria | 125 |
6.2 | One-Dimensional Equations and Linear Instability Analysis | 134 |
6.3 | Localization Analysis | 140 |
6.4 | Experimental Verification | 146 |
7 | Formation and Evolution of Shear Bands | 155 |
7.1 | Post-Instability Phenomena | 156 |
7.2 | Scaling and Approximations | 162 |
7.3 | Wave Trapping and Viscous Dissipation | 167 |
7.4 | The Intermediate Stage and the Formation of Adiabatic Shear Bands | 171 |
7.5 | Late Stage Behaviour and Post-Mortem Morphology | 179 |
7.6 | Adiabatic Shear Bands in Multi-Dimensional Stress States | 187 |
8 | Numerical Studies of Adiabatic Shear Bands | 194 |
8.1 | Objects, Problems and Techniques Involved in Numerical Simulations | 194 |
8.2 | One-Dimensional Simulation of Adiabatic Shear Banding | 199 |
8.3 | Simulation with Adaptive Finite Element Methods | 213 |
8.4 | Adiabatic Shear Bands in the Plane Strain Stress State | 218 |
9 | Selected Topics in Impact Dynamics | 229 |
9.1 | Planar Impact | 230 |
9.2 | Fragmentation | 237 |
9.3 | Penetration | 244 |
9.4 | Erosion | 255 |
9.5 | Ignition of Explosives | 261 |
9.6 | Explosive Welding | 268 |
10 | Selected Topics in Metalworking | 273 |
10.1 | Classification of Processes | 273 |
10.2 | Upsetting | 276 |
10.3 | Metalcutting | 286 |
10.4 | Blanking | 293 |
Appendices | 297 | |
A | Quick Reference | 298 |
B | Specific Heat and Thermal Conductivity | 301 |
C | Thermal Softening and Related Temperature Dependence | 312 |
D | Materials Showing Adiabatic Shear Bands | 335 |
E | Specification of Selected Materials Showing Adiabatic Shear Bands | 341 |
F | Conversion Factors | 357 |
References | 358 | |
Author Index | 369 | |
Subject Index | 375 |
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Mitochondria dynamics is crucial to many biological processes such as mitochondria fusion and fission, which is highly correlated to the mechanics of single mitochondria. However, the mechanobiological coupling of mitochondria has been poorly understood. Here membrane deformability and membrane tension of individual mitochondria isolated from MtDsRed labeled human embryonic T-Rex-293 kidney cells were measured using a micropipette aspiration assay. The results demonstrated that membrane deformation of isolated mitochondria exhibited an elastic transition phase followed by an equilibrium phase, and mitochondrial membrane tension was proportional to the area compressibility. It was also indicated that mitochondrial membrane deformability was significantly affected by physical chemical factors such as osmotic pressure or pH value, and was further correlated to mitochondrial functionality in different respiratory states and Ca2+ regulation. These findings provide a new insight into understanding the mechanical regulation of mitochondrial physiology.
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Based on birefringence, a building-block stacking technique is suggested in this paper. A solid-state optical morphological processor module is thus developed, which is an integration of a beam array generator submodule, an optical connector submodule, and a Pockels readout optical modulator. It is shown that the technique is compact in construction, simple for fabrication, and insensitive to the environment.