中国粮食生产的区域演进研究

Grain is one of the primary material conditions of the human survival and the grain production concerns the stability and development of the society directly. The regional patterns influence greatly on the grain production and the rational production distribution the regional comparative advantages and promotes grain production. This thesis starts with summarizing of the characteristics of changes and the overall trend of regional pattern of grain production of our country since 1949. Then it carries on network analyses to the factors, which influences the evolvement of regional grain production patterns of our country. And finally it gives some proposals to the grain production distribution in the future. The main content includes: Firstly, Reviewing the regional evolvement of grain production in our country, and analyzing the changes of the regional pattern of grain production of our country on the provincial scale and county scale separately, since 1949, especially since the reform and opening up policy. The main grain production areas are acting an important position in ensuring the national grain security, so this thesis analyses the main matter of the main grain production areas, forecasts the grain production situation in the future, and selects the Northeastern main grain production areas as the typical area to carry on the positive research. Secondly, this thesis analyzes the origin causes from two respects of natural and social economy of the regional evolvement pattern of grain production in China. Thirdly, based on the summarizing to the status of the regional pattern of the grain production, this thesis proposes the precept of the grain production distribution in the future in our country. Therefore, the areas of three major cereal crops, rice, wheat and corn, are confirmed on the basis of the comparative advantages. Finally, this thesis puts forward the security system of guaranteeing the grain production progressing steady in China. According to the above analysis, some conclusions have been achieved as follows: (1) The grain gross production gets on extricating itself from awkward position frequently while fluctuating greatly annually since 1949 in China. (2) Since the reform, its traditional regional pattern of grain production, the most of which was concentrated in the south area, has changed rapidly. China's center of gravity of grain production has shifted from the south to the north, and on the belts of latitude, the grain production has represented a trend of focusing to the middle area in China. (3) The main grain production areas play a very important role in ensuring China's food security. With their relative severe situation of the problems of agriculture, rural area and peasant, China has carried out a series of measures, which aim at improving the food-producing conditions of the main grain production areas, and enhancing the grain yields there. Under this condition, a forecast of the producing amount of the main grain production areas under the nation's self-supplying rate of over 95% shows that the increasing provision production in these areas can meet the demand of the country. (4) The natural and social economic factors influence together on the changes of the grain production regional pattern. Along with the state system transition and progress of agricultural science and technology, the regional pattern of grain production is affected heavier by the agricultural policy and technological elements. (5) The grain production will be concentrated to the middle province in the future, which economic development level being medium-sized; According to crop allocation, although the rice superiority production area located in the South, its comparative advantage index is little in some degree. Meanwhile, the wheat and corn superiority production areas are in the North mainly and its scale superiority and production level advantage are all comparatively obviously.

鸡胚吗啡用药对学习记忆和成瘾易感性的影响及其受体机制

Prenatal morphine exposure affects neural development of fetus by impairing learning and memory, and increasing susceptibility to morphine abuse. Because nervous systems have different developmental characteristics during different developmental stages, administration of morphine at different stages also has different effects on learning, memory, and susceptibility to morphine. Due to the precise developmental processes of neurotransmitter systems in chick embryo’s brain, and unique superiority of chick embryo model, the purpose of the present studies was to explore critical periods correlated to the memory impairment and the increasing susceptibility to morphine, via one-trial passive avoidance and conditioned place preference as behavior models. Then the possible roles of mu and delta opioid receptors as the possible mechanism were analyzed. Experiment 1 showed that injecting low dose of morphine (1 mg/kg) during the period embryonic 5 to 8 significantly impaired the function of learning and memory, worse than any other periods of the same treatment. Experiment 2 showed that injecting low dose of morphine during the period embryonic 17 to 20 significantly increased the susceptibility to morphine in the new-born chicks. The affected chicks acquired the morphine conditioned place preference more quickly, and maintained it much longer. Experiment 3 showed that during E5-8, injecting delta receptor antagonist naltrindole reversed the learning and memory impairment caused by morphine while delta receptor agonist DPDPE impaired learning and partial memory function. On the other hand, mu opioid receptors had little effect. As for E17-20, given naloxonazine can reverse the increases of susceptibility to morphine, and the mu receptor agonist DAGO cause the increases of susceptibility to morphine. Delta receptors have no effect. The above results demonstrated that prenatal morphine expousure at different developmental periods of chick embryo caused different influences on memory and susceptibility to morphine. That is, E5-8 is the critical period correlate to memory impairment; and E17-20 is the critical period correlate to susceptibility to morphine. Delta receptors were critical in learning and memory impairment while mu receptors in susceptibility.

Integration of ion-exchange chromatography fractionation with reversed-phase liquid chromatography-atmospheric pressure chemical ionization mass spectrometer and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for isolation and identification of compounds in Psoralea corylifolia

An approach for the separation and identification of components in a traditional Chinese medicine Psoralea corylifolia was developed. Ion-exchange chromatography (IEC) was applied for the fractionation of P corylifolia extract, and then followed by concentration of all the fractions with rotary vacuum evaporator. Each of the enriched fractions was then further separated on an ODS column with detection of UV absorbance and atmospheric pressure chemical ionization mass spectrometer (APCI/MS), respectively, and also analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) with matrix of oxidized carbon nanotubes. Totally more than 188 components in P. corylifolia extract were detected with this integrated approach, and 12 of them were preliminary identified according to their UV spectra and mass spectra performed by APCI/MS and MALDI-TOF/MS. The obtained analytical results not only demonstrated the powerful resolution of integration IEC fractionation with reversed-phase liquid chromatography (RPLC)-APCI/MS and MALDI-TOF/MS for analysis of compounds in a complex sample, but also exhibited the superiority of APCI/MS and MALDI-TOF/MS for identification of low-mass compounds, such as for study of traditional Chinese medicines (TCMs) and metabolome. (c) 2005 Published by Elsevier B.V.