48 resultados para Heart diseases - Experimental studies


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Experimental studies have been performed for horizontal two-phase air-water flows at normal and reduced gravity conditions in a square cross-section channel. The experiments at reduced gravity are conducted on board the Russian IL-76 reduced gravity airplane. Four flow patterns, namely bubble, slug, slug-annular transition and annular flows, are observed depending on the liquid and gas superficial velocities at both conditions. Semi-theoretical Weber number model is developed to include the shape influence on the slug-annular transition. It is shown that its prediction is in reasonable agreement with the experimental slug-annular transition under both conditions. For the case of two-phase gas-liquid flow with large value of the Froude number, the drift-flux model can predict well the observed boundary between bubble and slug flows.

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Poly(dimethylsiloxane) (PDMS) is usually considered as a dielectric material and the PDMS microchannel wall can be treated as an electrically insulated boundary in an applied electric field. However, in certain layouts of microfluidic networks, electrical leakage through the PDMS microfluidic channel walls may not be negligible, which must be carefully considered in the microfluidic circuit design. In this paper, we report on the experimental characterization of the electrical leakage current through PDMS microfluidic channel walls of different configurations. Our numerical and experimental studies indicate that for tens of microns thick PDMS channel walls, electrical leakage through the PDMS wall could significantly alter the electrical field in the main channel. We further show that we can use the electrical leakage through the PDMS microfluidic channel wall to control the electrolyte flow inside the microfluidic channel and manipulate the particle motion inside the microfluidic channel. More specifically, we can trap individual particles at different locations inside the microfluidic channel by balancing the electroosmotic flow and the electrophoretic migration of the particle.

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Field and experimental studies were conducted to investigate pathological characterizations and biochemical responses in the liver and kidney of the phytoplanktivorous bighead carp after intraperitoneal (i.p.) administration of microcystins (MCs) and exposure to natural cyanobacterial blooms in Meiliang Bay, Lake Taihu. Bighead carp in field and laboratory studies showed a progressive recovery of structure and function in terms of histological, cellular, and biochemical features. In laboratory study, when fish were i.p. injected with extracted MCs at the doses of 200 and 500 mu g MC- LReq/kg body weight, respectively, liver pathology in bighead carp was observed in a time dose-dependent manner within 24 h postinjection and characterized by disruption of liver structure, condensed cytoplasm, and the appearance of massive hepatocytes with karyopyknosis, karyorrhexis, and karyolysis. In comparison with previous studies on other fish, bighead carp in field study endured higher MC doses and longer-term exposure, but displayed less damage in the liver and kidney. Ultrastructural examination in the liver revealed the presence of lysosome proliferation, suggesting that bighead carp might eliminate or lessen cell damage caused by MCs through lysosome activation. Biochemically, sensitive responses in the antioxidant enzymes and higher basal glutathione concentrations might be responsible for their powerful resistance to MCs, suggesting that bighead carp can be used as biomanipulation fish to counteract cyanotoxin contamination.

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维生素(Vitamin)又称维他命,为“万年青”产品,是维持人体生命健康必需的一类低分子有机化合物质。维生素对人体健康的作用人们研究很多, 维生素可以增强人体对感染的抵抗力,降低出生缺陷及降低癌症和心脏病发病率等,一旦缺乏,肌体代谢就会失去平衡,免疫力下降,各种疾病,病毒就会趁虚而入;而维生素对作物影响的研究却很少。目前为止,尚无对用维生素浸种的方法来研究外源维生素是否对小麦种子萌发及幼苗生长起调节作用的报道,且对其在小麦抗逆性方面影响的研究甚少,对盐的胁迫抗性研究尚未有人报道。小麦(Triticum aestivum L.)属于拒盐的淡土性作物。盐害不利于小麦生长,严重影响小麦的产量和品质。本研究采用4 种不同维生素VB1、VC、VB6、VPP,分别对供试小麦品种川育12(红皮)、川育16(白皮)小麦浸种后,在一般自然条件下和逆境(盐胁迫条件)下,进行试验。探讨在正常情况下与在不同盐浓度条件下,各维生素及盐浓度对小麦发芽及幼苗生长的影响,并且比较两种不同皮色的小麦在相同盐胁迫条件下的差异表现,同时研究维生素处理的特异性,且哪种维生素对盐害缓解作用最佳。研究结果表明:在无盐胁迫(自然)条件下,对用4 种不同维生素VB1、VC、VB6、VPP 浸种小麦川育12、川育16 后的种子萌发及幼苗生长(幼苗的根长、根重、苗高、苗鲜重)的研究结果表明:4 种外源维生素浸种均对小麦发芽有调节作用,都能提高其最终发芽率。但是提高幅度有所差异。用VB6 浸种后的小麦提高幅度最多,VC 次之,VPP 提高幅度最小。同时,4 种外源维生素浸种对小麦种子的出芽速度及芽后长势也有一定的影响。VB6、VC 处理的小麦种子出芽速度最快,萌发后长势最好;VB1 出芽速度相对较慢,VPP 最慢,但都大于对照;VB1 处理长势略高于对照,VPP 处理的小麦长势则低于对照。从整体来看,VB6、VC处理促进效应明显, VB1 次之,而VPP 在某些方面无效甚至产生负效应。此外,相同的维生素处理对不同的品种的种子萌发、生长效果也存在差异,各种维生素作用于川育12 的效应均强于对川育16。进一步对幼苗根系TTC 还原力及幼苗叶片中硝酸还原酶活性进行测定、分析。研究发现:并非所有种类的维生素对幼苗根系TTC 还原力及幼苗叶片中硝酸还原酶活性的提高都有帮助。幼苗根系TTC 还原力在不同维生素处理下存在显著差异,而与小麦品种关系甚微。经VB6、VC 处理后,根系TTC 还原力测定值均显著高于对照,VB1 不明显,VPP 则略低于对照。VB6、VC 处理的幼苗叶片中硝酸还原酶的含量大于对照,VB1 与对照相差无几,而VPP 处理的川育12 幼苗叶片中的硝酸还原酶活性比对照CK 略高,而在川育16 中则略比对照CK 有所下降,呈现出抑制效应。综上结果表明:VB6、VC 具有促进种子发芽,幼苗生长及根系生长的作用,是较好的促生长剂;VPP 具有抑制作用,是较好的抑制剂,可进一步研究、开发利用。在盐胁迫条件下,对用4 种不同维生素VB1、VC、VB6、VPP 浸种川育12、川育16 后的种子萌发及幼苗生长(幼苗的根长、根重、苗高、苗鲜重)的研究结果表明:在不同盐浓度胁迫条件下, 各处理的种子萌发及幼苗生长均受到不同程度的抑制。随着盐浓度的增加, 发芽率、发芽指数和活力指数成下降趋势;幼苗的根长、根重、苗高、苗鲜重不断降低。4 种维生素处理间也表现出较大差异。VB6、VC 在每个处理中均保持对盐害的缓解作用,VB6 较VC 更易于促进发芽及幼苗生长。最终发芽率高,根系多、长、重,苗高高、重。而VB1、VPP 则表现出抑制作用。在高盐浓度150mM 时,4 种维生素浸种后的种子,其最终发芽率均不能达到40%,但VB6、VC 处理最终发芽率、苗重、根重均高于对照,VPP 最终发芽率、苗重、根重均低于对照。进一步对幼苗根系TTC 还原力及幼苗叶片中脯氨酸含量进行测定、分析。研究发现:不同盐浓度,不同维生素处理、不同品种间存在差异。随着盐浓度的增加(75mM,100mM,150mM),幼苗根系TTC 还原力活性成下降趋势,幼苗叶片中脯氨酸的积累量成上升趋势。VB6 处理脯氨酸含量增加最为明显,VC 次之,VPP 与对照接近,其变化幅度最小。经VB6、VC 处理后的幼苗根系还原强度,在不同盐浓度下,测定值均显著高于对照,VB1 不明显,VPP 则低于对照,产生负效应。此外,品种间表现不尽相同,相同的维生素处理,相同的盐浓度对不同的品种的种子萌发、生长效果也存在差异, 4 种维生素对川育16 的作用均强于川育12,但其影响趋势是一致的。说明VB6、VC 具有耐(抗)盐性,可以促进种子发芽和幼苗生长,是较好的耐(抗)盐拌种剂。 Vitamin is one kind of necessary low molecular compound for humans tosustain health and life. Lots of Studies have been done on the effectc of the vitaminsfor people. Vitamin can help people improve the body's natural resistance to disease,Drop the rate of birth defects、cacers and the incidence of the heart diseases. Ifpeople have less of them, the metabolism of the organism may throw off balance,immunity may drop off, and catch disease; Though the effects for Vitamin to thecrops are limited. up to now, there’s no one use soking seeds of wheats with vitaminsas a method, to study on how the effects will happen on the wheat seed germinationand seedling growth, and there are only few reserches on antireversion force forwheats ,none for the antireversion force in Sault stress condition.Wheat(Triticum aestivum L.)is sensitive to the salt, so the salt damage will doharm to wheat’s growth, it will have an unfavorable impact on the output and thequality of wheat.On this reaserch, we Soaking CHY12(red)、CHY16 (white) wheat seeds withVitamin C, B1, PP, B6 (50mg/L) as a pretreatment first. Then under two condition: one is in the normal environment the other is in different Salinity, we begin ourexperiments. Then disscuss on if the vitamin and salinity affect the wheat seedgermination and seedling growth, and what is the different between the two of them,the result shows that:Under the normal condition, after soaking seeds with VB1、VC、VB6、Vpp,we study on the their seed germination and the seeding growth(the root length andweights, The seedling heights and weights), it shows that all of those four kinds ofvitamin can adjust the seed germination, but different in The growth rate. VB6 isbest for increase, VC comes second,VPP is the worst. Meanwhile, those four vitaminalso have effect on the speed of the sprouting of the wheat. VB6、Vc can faster theseed germination most, and the seedlings are all doing well; VB1 do little effects onthe budding, Vpp is the worst, but all treatments are better than CK; but in Vi, VB1some what above the CK, while VPP lower than that. On the whole, the acceleratingeffect of VB6、VC are obvious, VB1 takes second place, but VPP in some aspects arenoneffective even have negative effect. Furthermore, different kind of seeds with thesame vitamin may different in seed germination and seedling growth, four vitaminson CHY16 is better than CHY12.More studies on TTC reductive capacity of roots and the activity of nitratereductase in the leaves, the reasult shows not all the vitamin can help the seedlings toimprove the TTC reductive capacity and the activity of nitrate reductase. TTCreductive capacity in different treatments shows significant differences,but notcorrelate to the variety of the wheat. The TTC reductive capacity of VB6、Vctreatments are all higher than CK, VB1 is nearly the same as CK, VPP is a littlelower than CK. Through the study of acivity of nitrate reductase, it shows that,VB6、VC are higher than CK ,VB1 is nearly the same as CK also, VPP is a little higher inthe CK of CHY12 but lower in CHY16. Through all the results above: VB6、Vc helpthe wheat seed germination, seedling growth and the growth of roots, is theperfectable factor of stimulating the growth; Vpp is a inhibition, that’ll be furtherreserch,and well develop and utilize in the future.Under the different Salinity condition, after soaking seeds with VB1、VC、VB6、Vpp,we study on the their seed germination and the seeding growth(the root lengthand weights, The seedling heights and weights), it shows that: under differentsalinity, the seed germination and the seedling growth of any treatment are inhibited.With the increase of the concentration, the germination rate, Vi、Gi all had fallen; theroot length and weight, the seedling heights and weights steadily sank down. There are also have pronounced difference between all treatments with four differentvitamins.VB6、VC in all treatments are alleviative the salt damage, VB6 is easier tocause to put forth buds than VC, and it’s quantitative value is the highest in theultimate germination rate, in root and seedlings’ hight and weight. Though the VPP、VB1 are seems to inhibite its growth. Under the high concentration150mM Nacl, theultimate germination rate in all treatments are below the 40%, but VB6、VC’squantitative values in any experiments are higher than CK,while VPP lower thanCK.Then we study on the TTC reductive capacity of roots and the content of Polinein leaves, the result shows that between the different salinity, different vitamintreatments, different varieties of the wheat have discrepancy.along with theincreasing concentraion of the salinity(75mM,100mM,150mM),TTC reductivecapacity of roots decreases, the accumulation of the content of Poline in leaves havean upward trend. The increase of VB6’s treatment are obviously, VC comessecond,VPP is nearly come up with CK, changes a little. In TTC reductive capacity of roots’s reserch, VB6、VC are higher than CK at any time,VB1 is not palpable,VPP is lower than CK, makes negative affect on wheat. In addition, varieties of thewheats are remain different, no matter it shows promoting or inhibiting, all fourvitamins have moreobvious effects on CHY16 than CHY12, but the tendency of theeffection are the same. It is say that VB6、VC can help wheat to standwith the saultwell, and promot in growth,they are the better reagent to mix with the seed.

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研究了应用射流泵输送油水两相管流时泵对下游管道中流型和压降的影响。实验管线为内径50mm的透明有机玻璃管,管线从入口到分离器长约35m,实验段由一个垂直倒U型管和一个长3m水平管组成。分别给出了不同入口条件下实验管段的流型图和压降图。结果表明:采用射流泵输送油水两相流动,对下游管道流型和油水乳化速度有着显著的影响,但对下游管道内的压降随混合流速和体积份额的变化趋势影响很小。

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通过实验的方法研究了金属长杆撞击带薄盖板约束炸药的引爆现象。观察带有随机偏航角的金属长杆以不同速度撞击炸药的响应情况。找出了金属长杆在不同入射角度和炸药约束条件下,炸药的冲击爆轰阈值。讨论了判别未知炸药发生爆轰、延迟爆轰、非爆轰性爆炸、点火后淬熄和不反应的试验测量手段和方法。结果表明:冲击引爆阈值速度,对于不覆板的裸炸药,随入射角度(0、30、45)的增加而增加;随着覆板厚度的增加而增加。炸药的侧向约束情况对发生延迟爆轰有影响。射弹偏航也是影响炸药引爆的因素之一。Jacobs 判据是关于炸药冲击引爆阈值的经验判据,它可以适用于8701 炸药,文中给出了对平头钢弹、钢覆板情况下,用实验数据拟合的Jacobs公式。由于其它机理引发延迟爆轰(XDT)的现象是存在的,Jacobs 判据对这类现象不适用。

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This article is the result of experimental studies of the rheologv, viscosities, surface tensions, and atomization of water-methanol and diesel emulsions. The Span 80 and Tween 60 are employed to make three emulsifying agents, Y01, Y02, and Y03, with viscosity of 1.32-1.5 Pa s and HLB values of 5.36, 4.83, and 4.51, respectively. In the water-in-oil emulsions, the aqueous phase is between 10% and 50%; the agent concentration added is 0.8-8.0%. The viscosity of the emulsions is 0.003-0.02 Pa s, and the surface tens ion is 0.04-0.1 N/m. The types and concentrations of agents significantly influence the viscosity of the emulsions, and the higher concentration of the aqueous phase (<50%) in creases the viscosities of the emulsions, especially for higher agent concentration. Interfacial membrane and HLB values of the agents can explain all these phenomena. Higher aqueous phase concentration and agent viscosity results in larger Sauter mean diameter.

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Thoroughly understanding AFM tip-surface interactions is crucial for many experimental studies and applications. It is important to realize that despite its simple appearance, the system of tip and sample surface involves multiscale interactions. In fact, the system is governed by a combination of molecular force (like the van der Waals force), its macroscopic representations (such as surface force) and gravitational force (a macroscopic force). Hence, in the system, various length scales are operative, from sub-nanoscale (at the molecular level) to the macroscopic scale. By integrating molecular forces into continuum equations, we performed a multiscale analysis and revealed the nonlocality effect between a tip and a rough solid surface and the mechanism governing liquid surface deformation and jumping. The results have several significant implications for practical applications. For instance, nonlocality may affect the measurement accuracy of surface morphology. At the critical state of liquid surface jump, the ratio of the gap between a tip and a liquid dome (delta) over the dome height (y(o)) is approximately (n-4) (for a large tip), which depends on the power law exponent n of the molecular interaction energy. These findings demonstrate that the multiscale analysis is not only useful but also necessary in the understanding of practical phenomena involving molecular forces. (c) 2007 Elsevier Ltd. All rights reserved.

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采用SHTB技术对纤维增强复合材料裂纹动态起裂行为进行了实验研究。使用应变片方法确定了裂纹的起裂时间,结合有限元数值模拟得到了裂纹的起裂韧性;同时观察了裂纹在冲击载荷作用下的裂纹起裂和扩展方式,分析了纤维的铺层角度对裂纹起裂和扩增的影响。

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This paper shows the result of experimental studies of the influence of viscosities, surface tensions on atomization characteristics of water/methanol and diesel emulsions. Three emulsifying agents Y01, Y02 and Y03, with viscosity of 1.32 ~ 1.5 Pa·s and HLB values of 5.36, 4.83 and 4.51 respectively was produced by Span 80 and Tween 60. In the W/O emulsions, the aqueous phase is between 10% and 50%; the agent concentration added is 0.8 ~ 8.0%. The viscosity of the emulsions is 0.003 ~ 0.02 Pa·s, and the surface tension is 0.04 ~ 0.1 N/m. The types and concentrations of agents and the aqueous phase ( < 50%) significantly influence the viscosity of the emulsions and the Sauter Mean Diameter, measured by Malvern Particle Analyzer SERIES 2600.

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微重力流体物理是微重力科学的重要组成部分,包括简单流体的许多新体系、气/液两相流动和传热以及复杂流体力学.微重力流体物理除其本身学术和应用的重要意义外,还与微重力燃烧学、空间生物技术和空间材料科学密切结合,促进了交叉学科的发展.利用我国返回式卫星和神舟飞船,进行了一批微重力科学的空间实验,使我国微重力科学迅速进展.本文主要介绍近10年来我国微重力流体科学的空间实验研究和主要学术成果.

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报道了利用皮秒激光驱动产生瞬态类镍银X射线激光的实验结果.采用一路脉冲宽度为数百皮秒的激光作为预脉冲,配合另一路皮秒激光作为主脉冲联合驱动平面靶,获得了一定强度的类镍银X射线激光输出,输出能量约为5-10nJ.

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We apply a scattering theory of nonperturbative quantum electrodynamics to study the photoelectron angular distributions (PADs) of a hydrogen atom irradiated by linearly polarized laser light. The calculated PADs show main lobes and jetlike structure. Previous experimental studies reveal that in a set of above-threshold-ionization peaks when the absorbed-photon number increases by one, the jet number also increases by one. Our study confirms this experimental observation. Our calculations further predict that in some cases three more jets may appear with just one-more-photon absorption. With consideration of laser-frequency change, one less jet may also appear with one-more-photon absorption. The jetlike structure of PADs is due to the maxima of generalized phased Bessel functions, not an indication of the quantum number of photoelectron angular momentum states.

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研究了两种新型D-π-D结构的芴类衍生物4-{7-[4-(二甲基胺)苯基]-9,9-二(2-乙基己基)-9H--2-}-N,N-二甲基苯胺[缩写为B(DMAP)F]和4-{2-[7-(4-氨基苯乙烯基)-9,9-二(2-乙基己基)-9H--2-]乙烯基}苯胺(缩写为BASF)在四氢呋喃(THF)和N,N-二甲基甲酰胺(DMF)中的线性吸收和单光子荧光行为,用脉冲宽度为38ps,重复频率为10Hz的1064nmNd;YAG脉冲激光研究了两种化合物的三光子吸收性质,结果表明:受溶剂效应的影响,两种化合物在

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羊草草原、大针茅草原和草甸草原是内蒙古温带典型草原地区的三种主要植被类型,本文以此为研究对象,应用时空替代、温室、网室、自然降水接移、养分添加等多种方法模拟未来可能发生的气候变化,研究了这些变化对上述草原植物群落和生态系统过程的直接和间接影响。主要研究结果如下: 1. 气候变暖及其诱导的土壤养分释放速率增加对植物群落有明显的影响,表现在种种植物群落在高度、盖度、密度和生物量等都有不同程度的变化。说明我国温带草原生态系统对气候变化反应敏感。 2. 在群落说平上,气候变暖直接或间接使地上生物量提高17%~90%,但在种群水平,不同种群对模拟气候变化的响应具有很强的个性,而不具普遍性,不同种群反应的大小、方向不同。因此由在不同群落进行研究得出的推论只有部分是可能的,并且即使观测到相类似的反应,它们内在的机制也很可能是不同的。 3. 气候变化显著地影响着凋落物的分解特征。但不同的气候变化情景下,凋落物分解过程的响应不同。在温度升高降水变化不大或升高的情景下,凋落物的分解速率将加快;在气温上升,降水明显下降的情景下,凋落物的分解速率将降低。 4. 草甸草原土壤碳素释放过程和氮素矿化过程对气候变暖有明显的响应。气候变暖将促进土壤有机碳的释放,使草甸草原土壤成为碳源,同时加速氮素矿化速率,在一定程度上提高土壤有效养分的浓度。 5. 在中小尺度上,海拔样带所是应用时空替代原理,研究陆地生态系统与气候变化的理想平台,生物量是综合反应气候变化对土壤-植物系统影响的敏感指标。 6. 草原土壤有机碳和氮在2m~3m的小尺度上存在空间自相关性,其空间自相关尺度受人类活动的影响。