Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup

A transmembrane protein gene, c1orf37-dup, was identified as a young gene specific to humans. It was derived from the conserved c1orf37 gene through retroposition after the divergence of human and chimpanzee. This gene has evolved rapidly driven by positi

无指盘臭蛙皮肤活性肽及其基因和在制药中的应用

本发明涉及一种无指盘臭蛙皮肤活性肽及及其基因和在制药中的应用，属于生物医学领域。无指盘臭蛙皮肤活性肽是无指盘臭蛙皮肤活性肽基因编码的一种单链多肽，分子量3015.63道尔顿，等电点10.3，多肽全序列一级结构为： Ala Thr Ala Leu Gly Leu Ser Ser Arg Gly Leu Leu Pro Ile Gly Phe Met Phe Lys Asp Thr Ile Arg Cys Arg Lys Tyr(ATALGLSSRGLLPIGFMFKDTIRCRKY)。编码无指盘臭蛙皮肤活性肽的基因由312个核苷酸组成，其中编码成熟无指盘臭蛙皮肤活性肽为第141-222位核苷酸。人工合成的无指盘臭蛙皮肤活性肽具有很强的抑制细菌和真菌生长的作用，可以作为制备病原微生物感染疾病的治疗药物被应用。无指盘臭蛙皮肤活性肽具有结构简单、人工合成方便、抗菌谱系广、抗菌活性强的特点。

人工养殖条件下暗纹东方鲀的生长发育特性

对连续3年人工养殖的暗纹东方鲀的体重、体长、肝重、肝体系数、性腺系数和肥满度等指标进行分析,并用体长、体重相关式W=aLb进行拟合,研究其生长、发育情况.结果表明:池养暗纹东方鲀体长与体重的相关式为W=0.0557L2.9029,性成熟前肝脏与体长的相关式为W=0.0033L3.1875,肥满度为0.05±0.01,明显高于野生暗纹东方鲀.通过对性腺系数和肝体系数的分析得出,池养暗纹东方鲀如果培育良好,性腺能较好地发育.

湖北食管癌HLA-DQB1的基因多态性

目的从基因水平探讨湖北地区汉族人食管癌 HEN-DQB1等位基因的遗传易感性.方法运用序列特异性引物聚合酶链反应技术,检测无亲缘关系湖北汉族健康人136例、食管癌组42例患者的 HLA-DQB1等位基因.SAS system 统计软件数据处理.结果湖北汉族人食管癌患者与正常人比较,HEN-DQB1*0301基因频率显著增高(0.2976 vs 0.1875),P=0.046,OR=1.835,病因分数=0.1354);两组间 HLA-DQB1其余各等位基因分布频率的比较,HLA-DQB1*0201(0.0

Communities of gastrointestinal helminths of fish in historically connected habitats: habitat fragmentation effect in a carnivorous catfish Pelteobagrus fulvidraco from seven lakes in flood plain of the Yangtze River, China

Background: Habitat fragmentation may result in the reduction of diversity of parasite communities by affecting population size and dispersal pattern of species. In the flood plain of the Yangtze River in China, many lakes, which were once connected with the river, have become isolated since the 1950s from the river by the construction of dams and sluices, with many larger lakes subdivided into smaller ones by road embankments. These artificial barriers have inevitably obstructed the migration of fish between the river and lakes and also among lakes. In this study, the gastrointestinal helminth communities were investigated in a carnivorous fish, the yellowhead catfish Pelteobagrus fulvidraco, from two connected and five isolated lakes in the flood plain in order to detect the effect of lake fragmentation on the parasite communities. Results: A total of 11 species of helminths were recorded in the stomach and intestine of P. fulvidraco from seven lakes, including two lakes connected with the Yangtze River, i.e. Poyang and Dongting lakes, and five isolated lakes, i.e. Honghu, Liangzi, Tangxun, Niushan and Baoan lakes. Mean helminth individuals and diversity of helminth communities in Honghu and Dongting lakes was lower than in the other five lakes. The nematode Procamallanus fulvidraconis was the dominant species of communities in all the seven lakes. No significant difference in the Shannon-Wiener index was detected between connected lakes (0.48) and isolated lakes (0.50). The similarity of helminth communities between Niushan and Baoan lakes was the highest (0.6708), and the lowest was between Tangxun and Dongting lakes (0.1807). The similarity was low between Dongting and the other lakes, and the similarity decreased with the geographic distance among these lakes. The helminth community in one connected lake, Poyang Lake was clustered with isolated lakes, but the community in Dongting Lake was separated in the tree. Conclusion: The similarity in the helminth communities of this fish in the flood-plain lakes may be attributed to the historical connection of these habitats and to the completion of the life-cycles of this fish as well as the helminth species within the investigated habitats. The diversity and the digenean majority in the helminth communities can be related to the diet of this fish, and to the lacustrine and macrophytic characters of the habitats. The lake isolation from the river had little detectable effect on the helminth communities of the catfish in flood-plain lakes of the Yangtze River. The low similarities in helminth communities between the Dongting Lake and others may just be a reflection of its unique water environment and anthropogenic alterations or fragmentation in this lake.

A silicon capacitive microphone based on oxidized porous silicon sacrificial technology

In this paper, a new capacitive microphone fabrication technology is proposed. It describes using the oxidized porous silicon sacrificial technology to make air gap and using KOH etching technique to make the backplate containing acoustic holes based on the principle that the heavy p(+)-doping silicon can be nearly etched in KOH solution. The innovation of the method is using oxidized porous silicon technology. The sensitivity of the fabricated microphone is from -55dB ( 1.78mV/Pa) to -45dB (5.6mV/Pa) in the frequency range of 500Hz to 25kHz. Its cut-off frequency is higher than 20kHz.

多组分粒子流化床半湿式烟气脱硫研究

在借鉴国内外现有主要烟气脱硫技术优点的基础上,该研究提出了一种应用多组分粒子流化床(MSFB)的半湿式烟气脱硫技术.在常温下,该研究探讨了MSFB的各种粒子的流态化特性,还进一步研究了多种粒子混合条件下流态化的机理,明确了MSFB正常操作的区域.通过合理的简化与理论上的解析,该研究对MSFB上段自由空间内液滴的传热问题进行了分析,认为MSFB烟气脱硫装置中,液滴下落过程的温度变化极微,可以忽略不计.通过热力学关系的分析,该文提出了MSFB烟气脱硫系统正常稳定操作应遵循的条件,并研究了实验过程中死床现象出现的原因.在250℃进口烟温下,该文通过一系列的实验,研究了MSFB中密相床内浆液的干燥机理.在150℃ˉ250℃较低温度范围内,该文实施了利用Ca(OH)<,2>脱硫剂浆液的模拟烟气脱硫试验,脱硫效率可达95%以上.该文还介绍了该技术的工业示范情况,比较系统地总结了在实际应用中MSFB所遇到的问题及相应采取的解决方案.对MSFB应用于工业实践的具体案例,该文通过细致的技术经济分析,以及与应用NaOH废液时的经济性的比较分析,证明了MSFB半湿式烟气脱硫的良好的技术经济性能. 

注入噪声对光纤激光器锁模启动的影响

国家自然科学基金资助课题(60537060)

主流无载气N_2-氧碘化学激光配气方式的数值优化

针对主流无载气、副流以氮气为载气的氧碘化学激光(COIL), 应用求解3维多组分化学反应流方程的数值方法, 对流场和物理化学的耦合过程进行细致研究, 对副流载气变化带来的问题及性能提升的手段、特别是合理的配气方式进行深入分析. 结果表明:传统的在亚声速段进行喷流的配气方式不适用于主流无载气N_2-COIL系统, 必须采用超声速段射流方式; 合理的流量配比条件下, 超声速段射流方式COIL光腔位置处增益可达1.5% cm~(-1); N_2-COIL流场边界层厚度明显减小, 拓宽了增益的有效分布区域

A study of the influence of initial liquid volume on the capillary flow in an interior corner under microgravity

In this work the influence of initial liquid volume on the capillary flow in an interior corner is studied systematically by microgravity experiments using the drop tower, under three different conditions: the Concus-Finn condition is satisfied,close to and dissatisfied. The capillary flow is studied by discussing the movement of tip of the meniscus in the corner. Experimental results show that with the increase of initial liquid volume the tip location increases for a given microgravity time, the achievable maximum tip velocity increases and the flow reaches its maximum tip velocity earlier However, the results for the three different conditions show some difference. (C) 2010 Elsevier Ltd All rights reserved