白鱀豚人工饲养21年

<正> 世界鲸类动物的人工饲养已经有100多年的历史,鲸类动物的人工饲养不但为人们提供了一种非常有趣的娱乐项目,而且为深入研究、繁殖和保护鲸类动物提供了很好的条件。我国鲸类动物的人工饲养于1965年由青岛海产博物馆从饲养江豚开始

Apoptosis induction on human hepatoma cells Hep G2 of decabrominated diphenyl ether (PBDE-209)

Polybrominated diphenyl ethers (PBDEs) are an important class of halogenated organic brominated flame retardants. Because of their presence in abiotic and biotic environments widely and their structural similarity to polychlorinated biphenyls (PCBs), concern has been raised on their possible adverse health effects to humans. This study was designed to determine the anti-proliferative, apoptotic properties of decabrominated diphenyl ether (PBDE-209), using a human hepatoma Hep G2 line as a model system. Hep G2 cells were cultured in the presence of PBDE-209 at various concentrations (1.0-100.0 mu mol/L) for 72 h and the percentage of cell viability was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. The results showed that PBDE-209 inhibited the cells viability in time and concentration-dependent characteristics at concentrations (10.0-100.0 mu mol/L). We found that anti-proliferative effect of PBDE-209 was associated with apoptosis on Hep G2 cells by determinations of morphological changes, cell cycle and apoptosis. Mechanism study showed that PBDE-209 could increase the generation of intracellular reactive oxygen species (ROS) concentration-dependently. Antioxidant N-acetylcyteine partially inhibited the increase of ROS. The mechanism for its hepatoma-inhibitory effects was the induction of cellular apoptosis through ROS generation. In addition, activity of lactate dehydrogenase (LDH) release increased when the cells incubated with PBDE-209 at various concentrations and times. These results suggested that PBDE-209 had the toxicity activity of anti-proliferation and induction of apoptosis in tumor cells in vitro. (c) 2007 Elsevier Ireland Ltd. All rights reserved.

欧洲21世纪数据加密标准候选算法简评

简要介绍了欧洲 NESSIE( new European schemes for signatures,integrity,and encryption)大计划最近公布的 17个分组密码算法的基本设计思想、最新分析结果及其有效性 .

21世纪的光学和光电子学讲座 第三讲信息网络与半导体光电子学

于2010-11-23批量导入

21世纪的光学和光电子学讲座 第二讲 硅基发光材料和器件研究

硅基发光材料和器件是实现光电子集成的关键。文章评述了目前取得较大进展的几种主要硅基发光材料和器件的研究，包括掺饵硅，多孔硅，纳米硅以及Si/SiO_2等超晶格结构材料。展望了这些不同硅基发光材料作为发光器件和在光电集成中的发展前景。