珠江口盆地流花11-1油田储层非均质性及流体分布规律研究

In order to discover the distribution law of the remaining oil, the paper focuses on the quantitative characterization of the reservoir heterogeneity and the distribution law of the fluid barrier and interbed, based on fine geological study of the reservoir in Liuhuall-1 oil field. The refined quantitative reservoir geological model has been established by means of the study of core analysis, logging evaluation on vertical well and parallel well, and seismic interpretation and prediction. Utilizing a comprehensive technology combining dynamic data with static data, the distribution characteristics, formation condition and controlling factors of remaining oil in Liuhuall-1 oil field have been illustrated. The study plays an important role in the enrichment regions of the remaining oil and gives scientific direction for the next development of the remaining oil. Several achievements have been obtained as follows: l.On the basis of the study of reservoir division and correlation,eight lithohorizons (layer A, B_1, B_2, B_3, C, D, E, and F) from the top to the bottom of the reservoir are discriminated. The reef facies is subdivided into reef-core facies, fore-reef facies and backreef facies. These three subfacies are further subdivided into five microfacies: coral algal limestone, coralgal micrite, coral algal clastic limestone, bioclastic limestone and foraminiferal limestone. In order to illustrate the distribution law of remaining oil in high watercut period, the stratigraphic structure model and sedimentary model are reconstructed. 2.1n order to research intra-layer, inter-layer and plane reservoir heterogeneity, a new method to characterize reservoir heterogeneity by using IRH (Index of Reservoir Heterogeneity) is introduced. The result indicates that reservoir heterogeneity is medium in layer B_1 and B_3, hard in layer A, B_2, C, E, poor in layer D. 3.Based on the study of the distribution law of fluid barrier and interbed, the effect of fluid battier and interbed on fluid seepage is revealed. Fluid barrier and interbed is abundant in layer A, which control the distribution of crude oil in reservoir. Fluid barrier and interbed is abundant relatively in layer B_2,C and E, which control the spill movement of the bottom water. Layer B_1, B_3 and D tend to be waterflooded due to fluid barrier and interbed is poor. 4.Based on the analysis of reservoir heterogeneity, fluid barrier and interbed and the distribution of bottom water, four contributing regions are discovered. The main lies on the north of well LH11-1A. Two minors lie on the east of well LH11-1-3 and between well LH11-1-3 and well LH11-1-5. The last one lies in layer E in which the interbed is discontinuous. 5.The parameters of reservoir and fluid are obtained recurring to core analysis, logging evaluation on vertical well and parallel well, and seismic interpretation and prediction. Theses parameters provide data for the quantitative characterization of the reservoir heterogeneity and the distribution law of the fluid barrier and interbed. 6.1n the paper, an integrated method about the distribution prediction of remaining oil is put forward on basis of refined reservoir geological model and reservoir numerical simulation. The precision in history match and prediction of remaining oil is improved greatly. The integrated study embodies latest trend in this research field. 7.It is shown that the enrichment of the remaining oil with high watercut in Liuhua 11-1 oil field is influenced by reservoir heterogeneity, fluid barrier and interbed, sealing property of fault, driving manner of bottom water and exploitation manner of parallel well. 8.Using microfacies, IRH, reservoir structure, effective thickness, physical property of reservoir, distribution of fluid barrier and interbed, the analysis of oil and water movement and production data, twelve new sidetracked holes are proposed and demonstrated. The result is favorable to instruct oil field development and have gotten a good effect.

7-11岁正常儿童和ADHD儿童故事重述能力及策略的发展

儿童的故事重述涉及工作记忆和抽象表征能力，是与儿童的日常学业任务密切联系。儿童能否把握时间线索来组织故事重述，反映的是儿童抽象出故事事件内在时间关系的能力，因此对儿童故事重述的探查可以揭示儿童抽象思维发展的一般规律和特点。本研究在前人研究的基础上，系统探查了7－11岁儿童故事重述能力及其策略的发展过程，探讨了时间线索对儿童故事重述的影响，并对ADHD儿童和正常儿童的故事重述及策略进行了比较。 主要研究结果如下： (1)7－11岁儿童故事重述能力总体上随年龄增长而提高，按正确顺序重述的事件数量增多，重述过程中提取和使用的时间线索也增加。其中7－9岁有较快速的发展。 (2)随故事中包含的事件数量的增加，故事难度增大，儿童的故事重述成绩有所下降，故事长度对7岁和9岁儿童的影响大于对11岁儿童的影响。 (3)有、无时间线索语词会影响儿童的故事重述。故事中包含时间语词线索有助于儿童的故事重述。11岁儿童的故事重述已不受有、无时间线索的影响，他们在无时间线索的条件下，更多地主动使用表示因果关系的语词来表征事件关系。 (4)ADHD儿童的故事重述能力在9岁到11岁有较快的发展。但总体而言，ADHD儿童对含有时间线索故事的重述能力显著差于正常儿童。 (5)故事再学习对ADHD儿童和正常儿童的故事重述都存在促进作用。但ADHD儿童故事再学习效果不如正常儿童，低龄儿童中差距尤其明显，随着年龄的增加，ADHD儿童与正常儿童故事再学习效果的差距逐渐缩小。 (6)不同年龄的儿童主要采用四种策略解决问题。随年龄增长，正常儿童和ADHD儿童中使用水平较高的内容主线和逻辑关系策略的人数都有所增加。但ADHD儿童中高水平策略使用人数比例仍低于正常儿童。

Hydroisomerization of long-chain alkane over Pt/SAPO-11 catalysts synthesized from nonaqueous media

SAPO-11 molecular sieves were synthesized from nonaqueous media. The effects of Si and Al sources as well as solvents on the catalytic performance of SAPO-11 were investigated by the hydroisomerization reaction of n-dodecane. The samples were characterized by XRD, XRF, N-2-adsorption, SEM, NH3-TPD, IR-NH3 and Si-29 CP MAS NMR. The SAPO-11 samples synthesized with tetraethoxysilane as the Si source showed higher Si incorporation contents than the SAPO molecular sieves prepared with polymeric Si sources (fumed silica and Si colloidal gel). The reaction results showed that Pt/SAPO-11 catalysts synthesized from ethylene glycol and glycerol media with the monomeric Si and Al sources (tetraethoxysilane, aluminum isopropoxide) exhibited higher catalytic activities than those catalysts with the polymeric Si or Al (pseudo-boehmite) sources, due to the larger external surface area and higher acidity of the former ones. Especially, the catalyst synthesized in an ethylene glycol medium possessed the highest catalytic activity. Over this catalyst, 88% conversion of n-dodecane was achieved at a low temperature of 250 degrees C.

Purification and characterization of recombinant truncated human interleukin-11 expressed as fusion protein in Escherichia coli

Mature human interleukin-11 (HuIL-11) is a cytokine consisting of 178 amino acid residues that results from scission of the N-terminal signal peptide, consisting of 21 amino acid residaues, from the corresponding nascent polypeptide. A DNA fragment encoding a truncated HuIL-11 (trHuIL-11), with an additional 5 amino acid residues removed from the N-terminus, was cloned into vector pGEX-2T between the BamHI site and the EcoRI site. Upon transformation with Escherichia coli BL21, the construct over-produced a glutathione S-transferase (GST)-fused protein in a soluble form after IPTG induction. The fusion protein was initially fractionated with butyl-Sepharose 4 fast flow column and by affinity chromatography using a GSH-Sepharose 4B column. On-site enzymatic release with thrombin gave the target protein at 96% purity as judged by SDS-PAGE and HPLC. Expression of the interleukin as a GST-fused protein thus greatly improved downstream processing. Subsequent biological activity assay suggested that trHuIL-11 had similar activity profile to the naturally produced sample and may be a promising candidate for further development as biopharmaceutical.