Singapore's biomedical science sector development strategy: is it sustainable?

This paper outlines the strategic efforts undertaken by Singapore to establish its national capability in the biomedical science sector, reviews the commercial base as a result of these efforts and compares Singapore's approach to the UK and the US development models, discusses the challenges that Singapore faces and raises some questions on the long term sustainability of the sector.

Laboratory measurement of strength mobilisation in kaolin: Link to stress history

This letter presents data from triaxial tests conducted as part of a research programme into the stress-strain behaviour of clays and silts at Cambridge University. To support findings from earlier research using databases of soil tests, eighteen CIU triaxial tests on speswhite kaolin were performed to confirm an assumed link between mobilisation strain (γ M=2) and overconsolidation ratio (OCR). In the moderate shear stress range (0.2c u to 0.8c u) the test data are essentially linear on log-log plots. Both the slopes and intercepts of these lines are simple functions of OCR.

Building damage assessment for deep excavations in Singapore and the influence of building stiffness

One of the biggest issues for underground construction in a densely built-up urban environment is the potentially adverse impact on buildings adjacent to deep excavations. In Singapore, a building damage assessment is usually carried out using a three-staged approach to assess the risk of damage caused by major underground construction projects. However, the tensile strains used for assessing the risk of building damage are often derived using deflection ratios and horizontal strains under 'greenfield' conditions. This ignores the effects of building stiffness and in many cases may be conservative. This paper presents some findings from a study on the response of buildings to deep excavations. Firstly, the paper discusses the settlement response of an actual building - the Singapore Art Museum - adjacent to a deep excavation. By comparing the monitored building settlement with the adjacent ground settlement markers, the influence of building stiffness in modifying the response to excavation-induced settlements is observed. Using the finite element method, a numerical study on the building response to movements induced by deep excavations found a consistent relationship between the building modification factor and a newly defined relative bending stiffness of the building. This relationship can be used as a design guidance to estimate the deflection ratio in a building from the greenfield condition. By comparing the case study results with the design guidance developed from finite element analysis, this paper presents some important characteristics of the influence of building stiffness on building damages for deep excavations.