86 resultados para SENSORLESS DRIVES
em Cambridge University Engineering Department Publications Database
Resumo:
A sensorless scheme is presented for a two-phase permanent-magnet linear machine targeted for use in marine wave-power generation. This is a field where system reliability is a key concern. The scheme is able to extract the effective inductance and back-emf of the machine's phases simultaneously from measurements of the current ripple present on the power electronic converter. These measurements can then be used to estimate position. An enhancement to the scheme in the presence of spatially-varying mutual inductance between phases allows more accurate and reliable tracking from indutance-based measurements than would otherwise be expected. This scheme is able to operate at any speed including, critically, when stationary. Experimental results show promise for the scheme, although some work to reduce the level of noise would be desirable. © 2013 IEEE.
Resumo:
The propensity of protein molecules to self-assemble into highly ordered, fibrillar aggregates lies at the heart of understanding many disorders ranging from Alzheimer's disease to systemic lysozyme amyloidosis. In this paper we use highly accurate kinetic measurements of amyloid fibril growth in combination with spectroscopic tools to quantify the effect of modifications in solution conditions and in the amino acid sequence of human lysozyme on its propensity to form amyloid fibrils under acidic conditions. We elucidate and quantify the correlation between the rate of amyloid growth and the population of nonnative states, and we show that changes in amyloidogenicity are almost entirely due to alterations in the stability of the native state, while other regions of the global free-energy surface remain largely unmodified. These results provide insight into the complex dynamics of a macromolecule on a multidimensional energy landscape and point the way for a better understanding of amyloid diseases.
