Enduring Borderlands: the Marches of Ireland and Wales in the Early Modern Period

This joint chapter explores similarities and differences between two borderlands within the early modern ‘British’ state – the marches of Ireland and Wales. In some respects, the two regions were very different, most fundamentally because the Irish march remained militarised throughout the Tudor period, while Welsh society was markedly more peaceful. However, there was also much in common. In the later middle ages both marches were frontiers between the expanding Anglo-Normans and native Celtic society. The notion that the march separated ‘civility’ from ‘savagery’ was an enduring one: despite the efforts of the Tudors to impose centralisation and uniformity throughout its territories, there remained institutions, structures of power, and mentalities which ensured that both sets of marches were still in existence by the end of the 16th century. This chapter explores the reasons for the endurance of these borderlands, and indicates how political reforms of the 16th century caused the perception – and sometimes the very location – of the marches to alter.

The role of adaptive thermal comfort in the prediction of the thermal performance of a modern mixed-mode office building in the UK under climate change

Climate change is becoming a serious issue for the construction industry, since the time scales at which climate change takes place can be expected to show a true impact on the thermal performance of buildings and HVAC systems. In predicting this future building performance by means of building simulation, the underlying assumptions regarding thermal comfort conditions and the related heating, ventilating and air conditioning (HVAC) control set points become important. This article studies the thermal performance of a reference office building with mixedmode ventilation in the UK, using static and adaptive thermal approaches, for a series of time horizons (2020, 2050 and 2080). Results demonstrate the importance of the implementation of adaptive thermal comfort models, and underpin the case for its use in climate change impact studies. Adaptive thermal comfort can also be used by building designers to make buildings more resilient towards change. © 2010 International Building Performance Simulation Association (IBPSA).

BarraCUDA – a Fast Sequence Mapping Software using Graphics Processing Units

High-throughput DNA sequencing (HTS) instruments today are capable of generating millions of sequencing reads in a short period of time, and this represents a serious challenge to current bioinformatics pipeline in processing such an enormous amount of data in a fast and economical fashion. Modern graphics cards are powerful processing units that consist of hundreds of scalar processors in parallel in order to handle the rendering of high-definition graphics in real-time. It is this computational capability that we propose to harness in order to accelerate some of the time-consuming steps in analyzing data generated by the HTS instruments. We have developed BarraCUDA, a novel sequence mapping software that utilizes the parallelism of NVIDIA CUDA graphics cards to map sequencing reads to a particular location on a reference genome. While delivering a similar mapping fidelity as other mainstream programs , BarraCUDA is a magnitude faster in mapping throughput compared to its CPU counterparts. The software is also capable of supporting multiple CUDA devices in parallel to further accelerate the mapping throughput. BarraCUDA is designed to take advantage of the parallelism of GPU to accelerate the mapping of millions of sequencing reads generated by HTS instruments. By doing this, we could, at least in part streamline the current bioinformatics pipeline such that the wider scientific community could benefit from the sequencing technology. BarraCUDA is currently available at http://seqbarracuda.sf.net

Modern challenges facing turbomachinery aeroacoustics

In this review we describe current scientific and technological issues in the quest to reduce aeroengine noise, in the face of predicted rapid increases in the volume of air traffic, on the one hand, and increasingly strict environmental regulation, on the other. Alongside conventional ducted turbofan designs, new open-rotor contra-rotating power plants are currently under development, which present their own noise challenges. The key sources of tonal and broadband noise, and the way in which noise propagates away from the source, are surveyed in both cases. We also consider in detail two key aspects underpinning the flow physics that continue to receive considerable attention, namely the acoustics of swirling flow and unsteady flow-blade interactions. Finally, we describe possible innovations in open-rotor engine design for low noise.