Engineering change impact on product development processes

This paper presents a method to manage Engineering Changes (EC) during the product development process, which is seen to be a complex system. The ability to manage engineering changes efficiently reflects the agility of an enterprise. Although there are unnecessary ECs that should be avoided, many of the ECs are actually beneficial. The proposed method explores the linkages between the product development process features and product specifications dependencies. It suggests ways of identifying and managing specification dependencies to support the Engineering Change Management process. Furthermore, the impacts of an EC on the product specifications as well as on the process organization are studied. © 2009 World Scientific Publishing Company.

Effect of soil conditions on uplift of underground structures in liquefied soil

In an earthquake, underground structures located in liquefiable soil deposits are susceptible to floatation following an earthquake event due to their lower unit weight relative to the surrounding saturated soil. Such uplift response of the buoyant structure is influenced by the soil it is buried in. In the case of a liquefiable soil deposit, the soil can lose its shear strength significantly in the event of an earthquake. If the soil liquefies fully, the buoyant structure can float towards the soil surface. However, a partly liquefied soil deposit retains some of its initial shear strength and resists the uplift. This paper discusses the different soil conditions and their influence on the uplift response of buoyant structures. © 2012 World Scientific Publishing Company.

Rigid containment walls for liquefaction remediation

Many typical ground improvement techniques that are used for liquefaction remediation, such as in situ densification, are not appropriate for application under existing buildings and more novel techniques are required. This paper describes centrifuge tests investigating the performance of rigid containment walls as a liquefaction remediation method. A simple frame structure, founded on a deep layer of loose, liquefiable sand was tested under earthquake shaking. Centrifuge tests were then carried out with containment walls around the base of the structure, extending through the full depth of the liquefiable layer and also partial depth. It is found that rigid containment walls can be very effective in reducing structural settlements primarily by preventing lateral movement of the foundation sand but the impermeability of the walls may also be important. Improvements in structural settlement are observed even when the walls do not extend through the full depth of the liquefiable layer, if the depth of the walls is greater than the depth of the free field liquefaction. In addition, it is found that the accelerations of the structure are not increased, provided there is no rigid, structural connection between the structure and the containment walls. © 2012 World Scientific Publishing Company.

Biofunctionalization of PET/SiO2 surfaces for single molecule experiments and medical applications

PET/SiO2 layers were chemically modified to maintain immobilization of functional single molecules. GFP molecules provide an ideal system due to their stability and intrinsic fluorescence. GFP in vivo biotinylated within its NH2-terminal region and attached on the substrate via the biotinstreptavidin bond was further investigated with confocal microscopy, atomic force microscopy (AFM) and spectroscopic ellipsometry (SE). AFM revealed monolayered donut-like structures representing assemblies of biotinstreptavidinbiotinGFP immobilized onto PET/SiO2 surfaces via mPEG. In particular, regions with an approximate height of 12 nm, which approaches the molecular dimensions of the above complex given by molecular modeling, could be detected. The dimensions of the donut-like structures suggest a close-to-each-other positioning of the GFP molecules - which, however, retain their functionality, as evidenced by confocal microscopy. © 2011 World Scientific Publishing Company.