Electrical and optical spectroscopy for quantitative screening of hepatic steatosis in donor livers.

Macro-steatosis in deceased donor livers is increasingly prevalent and is associated with poor or non-function of the liver upon reperfusion. Current assessment of the extent of steatosis depends upon the macroscopic assessment of the liver by the surgeon and histological examination, if available. In this paper we demonstrate electrical and optical spectroscopy techniques which quantitatively characterize fatty infiltration in liver tissue. Optical spectroscopy showed a correlation coefficient of 0.85 in humans when referenced to clinical hematoxylin and eosin (H&E) sections in 20 human samples. With further development, an optical probe may provide a comprehensive measure of steatosis across the liver at the time of procurement.

Performance optimization of adaptive loading algorithms for SMF-based optical OFDM transceivers

Detailed investigations of the effectiveness of three widely adopted optical orthogonal frequency division multiplexing (OOFDM) adaptive loading algorithms, including power loading (PL), bit loading (BL), and bit-and-power loading (BPL), are undertaken, over < 100km single-mode fibre (SMF) system without incorporating inline optical amplification and chromatic dispersion (CD) compensation. It is shown that the BPL (PL) algorithm always offers the best (worst) transmission performance. The absolute transmission capacity differences between these algorithms are independent of transmission distance and launched optical power. Moreover, it is shown that in comparison with the most sophisticated BPL algorithm, the simplest PL algorithm is effective in escalating the OOFDM SMF links performance to its maximum potential. On the other hand, when employing a large number of subcarriers and a high digital-to-analogue DAC)/analogue-to-digital (ADC) sampling rate, the sophisticated BPL algorithm has to be adopted. © 2011 IEEE.