Designing for validation of medical devices and equipment

Validation is important in the design, development and production of medical devices since effective and appropriate validation plays a vital role in defining the success of a product in both technical and economic terms. Regulations and quality standards lay out the requirements for product validation, but it is left to each individual manufacturer to establish and maintain their own validation procedures. More recently, there has also been a change of emphasis in the regulations and standards that encourage the integration of validation into the development process. However, this poses particular challenges to the manufacturer since there is a distinct lack of guidance to assist this integration. This workbook provides the first real guidance on good design practices for medical device development. It has been developed through extensive consultation with device manufacturers and analysis of regulatory requirements. The approach is intended to assist manufacturers in meeting the new regulations.

Analysis of document-mining techniques and tools for technology intelligence: Discovering knowledge from technical documents

This research proposes a method for extracting technology intelligence (TI) systematically from a large set of document data. To do this, the internal and external sources in the form of documents, which might be valuable for TI, are first identified. Then the existing techniques and software systems applicable to document analysis are examined. Finally, based on the reviews, a document-mining framework designed for TI is suggested and guidelines for software selection are proposed. The research output is expected to support intelligence operatives in finding suitable techniques and software systems for getting value from document-mining and thus facilitate effective knowledge management. Copyright © 2012 Inderscience Enterprises Ltd.

A decoupled whole-building simulation engine for rapid exhaustive search of low-carbon and low-energy building refurbishment options

This paper presents the development of a new building physics and energy supply systems simulation platform. It has been adapted from both existing commercial models and empirical works, but designed to provide expedient exhaustive simulation of all salient types of energy- and carbon-reducing retrofit options. These options may include any combination of behavioural measures, building fabric and equipment upgrades, improved HVAC control strategies, or novel low-carbon energy supply technologies. We provide a methodological description of the proposed model, followed by two illustrative case studies of the tool when used to investigate retrofit options of a mixed-use office building and primary school in the UK. It is not the intention of this paper, nor would it be feasible, to provide a complete engineering decomposition of the proposed model, describing all calculation processes in detail. Instead, this paper concentrates on presenting the particular engineering aspects of the model which steer away from conventional practise. © 2011 Elsevier Ltd.

Validation of Vision Tracking at Egnatia Odos Motorway

Tracking applications provide real time on-site information that can be used to detect travel path conflicts, calculate crew productivity and eliminate unnecessary processes at the site. This paper presents the validation of a novel vision based tracking methodology at the Egnatia Odos Motorway in Thessaloniki, Greece. Egnatia Odos is a motorway that connects Turkey with Italy through Greece. Its multiple open construction sites serves as an ideal multi-site test bed for validating construction site tracking methods. The vision based tracking methodology uses video cameras and computer algorithms to calculate the 3D position of project related entities (e.g. personnel, materials and equipment) in construction sites. The approach provides an unobtrusive, inexpensive way of effectively identifying and tracking the 3D location of entities. The process followed in this study starts by acquiring video data from multiple synchronous cameras at several large scale project sites of Egnatia Odos, such as tunnels, interchanges and bridges under construction. Subsequent steps include the evaluation of the collected data and finally, performing the 3D tracking operations on selected entities (heavy equipment and personnel). The accuracy and precision of the method's results is evaluated by comparing it with the actual 3D position of the object, thus assessing the 3D tracking method's effectiveness.