Ultrasound elastography as an adjuvant to conventional ultrasound in the preoperative assessment of axillary lymph nodes in suspected breast cancer: a pilot study.

AIMS: To compare the performance of ultrasound elastography with conventional ultrasound in the assessment of axillary lymph nodes in suspected breast cancer and whether ultrasound elastography as an adjunct to conventional ultrasound can increase the sensitivity of conventional ultrasound used alone. MATERIALS AND METHODS: Fifty symptomatic women with a sonographic suspicion for breast cancer underwent ultrasound elastography of the ipsilateral axilla concurrent with conventional ultrasound being performed as part of triple assessment. Elastograms were visually scored, strain measurements calculated and node area and perimeter measurements taken. Theoretical biopsy cut points were selected. The sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV) were calculated and receiver operating characteristic (ROC) analysis was performed and compared for elastograms and conventional ultrasound images with surgical histology as the reference standard. RESULTS: The mean age of the women was 57 years. Twenty-nine out of 50 of the nodes were histologically negative on surgical histology and 21 were positive. The sensitivity, specificity, PPV, and NPV for conventional ultrasound were 76, 78, 70, and 81%, respectively; 90, 86, 83, and 93%, respectively, for visual ultrasound elastography; and for strain scoring, 100, 48, 58 and 100%, respectively. There was no significant difference between any of the node measurements CONCLUSIONS: Initial experience with ultrasound elastography of axillary lymph nodes, showed that it is more sensitive than conventional ultrasound in detecting abnormal nodes in the axilla in cases of suspected breast cancer. The specificity remained acceptable and ultrasound elastography used as an adjunct to conventional ultrasound has the potential to improve the performance of conventional ultrasound alone.

Comment and reply on the 'assessment of combustion and submodels for turbulent nonpremixed hydrocarbon flames'

In deriving the flamelet model for nonpremixed combustion certain terms, but not the unsteady term, are assumed to be negligible. This results in a relation between all reacting scalars and the mixture fraction as independent variable. An ideal test of the flamelet assumption can be based on direct numerical simulation (DNS) data, if all reacting scalars are conditioned on mixture fraction and conditional moments are evaluated. The fundamental assumption of the flamelet model are unwillingly justified. The unsteady and steady formulations of the same equations are compared and found that unsteadiness is important in an unsteady simulation.

Analysis and performance assessment of 6-pulse inverter-fed 3-phase and 6-phase induction machines

The paper describes a model for a 6-phase induction motor driven by an inverter operating in a 6-pulse (square wave) mode. The model is implemented and performance, in terms of torque, current, efficiency and pulsating torque, compared to the performance of a 3-phase motor (both sine and 6-pulse supplied). The models are verified experimentally, in particular the efficiency performance, and it is illustrated that the improvement in inverter efficiency when in 6-pulse operating mode may improve the performance of the overall system. © 2005 IEEE.

Assessment of CFD models for shock boundary-layer interaction

A workshop on the computational fluid dynamics (CFD) prediction of shock boundary-layer interactions (SBLIs) was held at the 48th AIAA Aerospace Sciences Meeting. As part of the workshop numerous CFD analysts submitted solutions to four experimentally measured SBLIs. This paper describes the assessment of the CFD predictions. The assessment includes an uncertainty analysis of the experimental data, the definition of an error metric and the application of that metric to the CFD solutions. The CFD solutions provided very similar levels of error and in general it was difficult to discern clear trends in the data. For the Reynolds Averaged Navier-Stokes methods the choice of turbulence model appeared to be the largest factor in solution accuracy. Large-eddy simulation methods produced error levels similar to RANS methods but provided superior predictions of normal stresses.