6 resultados para elderly men
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Duración (en horas): De 11 a 20 horas. Nivel educativo: Grado
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Eguíluz, Federico; Merino, Raquel; Olsen, Vickie; Pajares, Eterio; Santamaría, José Miguel (eds.)
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Eterio Pajares, Raquel Merino y José Miguel Santamaría (eds.)
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Background: Vitamin K has been related to glucose metabolism, insulin sensitivity and diabetes. Because inflammation underlies all these metabolic conditions, it is plausible that the potential role of vitamin K in glucose metabolism occurs through the modulation of cytokines and related molecules. The purpose of the study was to assess the associations between dietary intake of vitamin K and peripheral adipokines and other metabolic risk markers related to insulin resistance and type 2 diabetes mellitus. Methods: Cross-sectional and longitudinal assessments of these associations in 510 elderly participants recruited in the PREDIMED centers of Reus and Barcelona (Spain). We determined 1-year changes in dietary phylloquinone intake estimated by food frequency questionnaires, serum inflammatory cytokines and other metabolic risk markers. Results: In the cross-sectional analysis at baseline no significant associations were found between dietary phylloquinone intake and the rest of metabolic risk markers evaluated, with exception of a negative association with plasminogen activator inhibitor-1. After 1-year of follow-up, subjects in the upper tertile of changes in dietary phylloquinone intake showed a greater reduction in ghrelin (-15.0%), glucose-dependent insulinotropic peptide (-12.9%), glucagon-like peptide-1 (-17.6%), IL-6 (-27.9%), leptin (-10.3%), TNF (-26.9%) and visfatin (-24.9%) plasma concentrations than those in the lowest tertile (all p<0.05). Conclusion: These results show that dietary phylloquinone intake is associated with an improvement of cytokines and other markers related to insulin resistance and diabetes, thus extending the potential protection by dietary phylloquinone on chronic inflammatory diseases.
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El trabajo que se presenta a continuación es un plan de marketing para la empresa Gastronomía Vasca, concretamente, para el desarrollo de uno de sus servicios, Menú 2.0, el cual se creó en 2012 y para el que se pretende establecer el camino de crecimiento para el periodo 2015/2016. Para la determinación del modo en el que desarrollar este crecimiento, en primer lugar, se va a analizar la situación en la que se encuentra actualmente tanto a nivel interno como respecto del entorno. Esto nos permitirá detectar las fortalezas y las debilidades que presenta la empresa, así como las amenazas y las oportunidades que le ofrece el entorno, y a partir de las cuales se definirán los objetivos que deben establecerse para Menú 2.0. Por último, tras la definición de los objetivos, se establecerán las estrategias y las acciones que se han de realizar para el cumplimiento de éstos. Además, se establecerán métodos de control para que la empresa pueda medir durante el desarrollo del plan, el cumplimiento de los objetivos planteados.
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To achieve the apparently simple Periodic Table of the Elements has implied tremendous efforts over thousands of years. In this paper we present a brief history of the discovery of the chemical elements from prehistory to the present day, revealing the controversies that arose on the way and claiming the important work performed by alchemists in the advancement of knowledge. This is especially important if we consider that alchemy had a period of existence of many thousands of years, while the "Chemistry", officially established as a science in the eighteenth century, has operated as such for only a few hundred years. Even so, if we consider the progress of discovery and isolation of chemical elements throughout history, it can be observed that the number of elements identified is achieved mainly in the nineteenth and twentieth centuries, reflecting the development of instrumental techniques, that facilitated this task.