Augmented Peter Pan: un cuento multilingüe con Realidad Aumentada

[SPA] El objetivo de este Trabajo de Fin de Grado ha sido diseñar un cuento multilingüe que incorpora una innovación tecnológica, la Realidad Aumentada, para favorecer el proceso de enseñanza-aprendizaje lingüístico en la escuela. Para ello, hemos analizado algunos cuentos con Realidad Aumentada que se pueden encontrar en el mercado. Al no encontrar ningún cuento que cumpliese nuestras expectativas, hemos creado un cuento multilingüe con Realidad Aumentada adaptando el cuento clásico “Peter Pan”, que cumple los objetivos de fomentar el aprendizaje de diferentes idiomas y el gusto por la lectura, valorar las lenguas inmigrantes en las aulas y promover el uso de las TIC.

Uso de la Realidad Aumentada para facilitar la lectura e interpretación de planos

[ES] Este proyecto genera productos adicionales de trabajos también disponibles en el repositori, en concreto:

[A_Llodio_Yermo] Documentación geométrica para la puesta en valor y difusión social del Santuario de Santa María del Yermo (Laudio/Llodio, Álava)

[ES] La iglesia de Santa María tiene una planta de unos 22x18 metros y cuenta con tres pórticos (sur, oeste y norte) así como una espadaña exenta. Adyacente al sudeste se encuentra la ermita de Santa Lucía. Las excavaciones arqueológicas de dos zonas de unos 6 x 3 metros en el interior y el exterior de la iglesia sirven como hilo conductor a las jornadas de puertas abiertas al público.

Interculturalidad y realidad aumentada: una colección de cuentos para trabajar en el aula

Este trabajo presenta un diagnóstico llevado a cabo en un aula de segundo de Educación Primaria con alto índice de inmigración, que se conocía con anterioridad por unas prácticas del Grado de Educación Primaria llevadas a cabo en esa escuela. A partir de los resultados de este diagnóstico se ha creado una colección de cuentos de las culturas existentes en el aula seleccionada. Además, en el cuento se integra como innovación el uso de la Realidad Aumentada y se pretende, también, fomentar entre el alumnado el gusto de la lectura desde el punto de vista intercultural, aspecto cada vez más visible en los centros de enseñanza actuales.

The role of the term spread in an augmented Taylor rule: An empirical investigation

Using US data for the period 1967:5-2002:4, this paper empirically investigates the performance of an augmented version of the Taylor rule (ATR) that (i) allows for the presence of switching regimes, (ii) considers the long-short term spread in addition to the typical variables, (iii) uses an alternative monthly indicator of general economic activity suggested by Stock and Watson (1999), and (iv) considers interest rate smoothing. The estimation results show the existence of switching regimes, one characterized by low volatility and the other by high volatility. Moreover, the scale of the responses of the Federal funds rate to movements in the term spread, inflation and the economic activity index depend on the regime. The estimation results also show robust empirical evidence that the ATR has been more stable during the term of office of Chairman Greenspan than in the pre-Greenspan period. However, a closer look at the Greenspan period shows the existence of two alternative regimes and that the response of the Fed funds rate to inflation has not been significant during this period once the term spread is considered.

Fine mapping and functional analysis of the multiple sclerosis risk gene CD6

CD6 has recently been identified and validated as risk gene for multiple sclerosis (MS), based on the association of a single nucleotide polymorphism (SNP), rs17824933, located in intron 1. CD6 is a cell surface scavenger receptor involved in T-cell activation and proliferation, as well as in thymocyte differentiation. In this study, we performed a haptag SNP screen of the CD6 gene locus using a total of thirteen tagging SNPs, of which three were non-synonymous SNPs, and replicated the recently reported GWAS SNP rs650258 in a Spanish-Basque collection of 814 controls and 823 cases. Validation of the six most strongly associated SNPs was performed in an independent collection of 2265 MS patients and 2600 healthy controls. We identified association of haplotypes composed of two non-synonymous SNPs [rs11230563 (R225W) and rs2074225 (A257V)] in the 2nd SRCR domain with susceptibility to MS (Pmax(T) permutation=161024). The effect of these haplotypes on CD6 surface expression and cytokine secretion was also tested. The analysis showed significantly different CD6 expression patterns in the distinct cell subsets, i.e. – CD4+ naı¨ve cells, P = 0.0001; CD8+ naı¨ve cells, P,0.0001; CD4+ and CD8+ central memory cells, P = 0.01 and 0.05, respectively; and natural killer T (NKT) cells, P = 0.02; with the protective haplotype (RA) showing higher expression of CD6. However, no significant changes were observed in natural killer (NK) cells, effector memory and terminally differentiated effector memory T cells. Our findings reveal that this new MS-associated CD6 risk haplotype significantly modifies expression of CD6 on CD4+ and CD8+ T cells.

Towards a Comprehensive Approach to Quantifying and Mapping Ecosystem Services Flows

25 p.

BAMS: A Tool for Supervised Burned Area Mapping Using Landsat Data

A new supervised burned area mapping software named BAMS (Burned Area Mapping Software) is presented in this paper. The tool was built from standard ArcGIS (TM) libraries. It computes several of the spectral indexes most commonly used in burned area detection and implements a two-phase supervised strategy to map areas burned between two Landsat multitemporal images. The only input required from the user is the visual delimitation of a few burned areas, from which burned perimeters are extracted. After the discrimination of burned patches, the user can visually assess the results, and iteratively select additional sampling burned areas to improve the extent of the burned patches. The final result of the BAMS program is a polygon vector layer containing three categories: (a) burned perimeters, (b) unburned areas, and (c) non-observed areas. The latter refer to clouds or sensor observation errors. Outputs of the BAMS code meet the requirements of file formats and structure of standard validation protocols. This paper presents the tool's structure and technical basis. The program has been tested in six areas located in the United States, for various ecosystems and land covers, and then compared against the National Monitoring Trends in Burn Severity (MTBS) Burned Area Boundaries Dataset.

Epitope mapping of antibodies to alpha-synuclein in LRRK2 mutation carriers, idiopathic Parkinson disease patients, and healthy controls

Alpha-synuclein (Snca) plays a major role in Parkinson disease (PD). Circulating anti-Snca antibodies has been described in PD patients and healthy controls, but they have been poorly characterized. This study was designed to assess the prevalence of anti-Snca reactivity in human subjects carrying the LRRK2 mutation, idiopathic PD (iPD) patients, and healthy controls and to map the epitopes of the anti-Snca antibodies. Antibodies to Snca were detected by ELISA and immunoblotting using purified recombinant Snca in plasma from individuals carrying LRRK2 mutations (104), iPD patients (59), and healthy controls (83). Epitopes of antibodies were mapped using recombinant protein constructs comprising different regions of Snca. Clear positive anti-Snca reactivity showed no correlation with age, sex, years of evolution, or the disability scores for PD patients and anti-Snca reactivity was not prevalent in human patients with other neurological or autoimmune diseases. Thirteen of the positive individuals were carriers of LRRK2 mutations either non-manifesting (8 out 49 screened) or manifesting (5 positive out 55), three positive (out of 59) were iPD patients, and five positive (out of 83) were healthy controls. Epitope mapping showed that antibodies against the N-terminal (a.a. 1-60) or C-terminal (a.a. 109-140) regions of Snca predominate in LRRK2 mutation carriers and iPD patients, being N122 a critical amino acid for recognition by the anti-C-terminal directed antibodies. Anti-Snca circulating antibodies seem to cluster within families carrying the LRRK2 mutation indicating possible genetic or common environmental factors in the generation of anti-Snca antibodies. These results suggest that case-controls' studies are insufficient and further studies in family cohorts of patients and healthy controls should be undertaken, to progress in the understanding of the possible relationship of anti-Snca antibodies and PD patholog

Density-potential mapping in the standard and quantum electrodynamical time-dependent density functional theory

131 p.