40 resultados para Huerta, Francisco Manuel de .


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Fecha: 15-3-1935 (>1970 reproduccin) / Unidad de instalacin: Carpeta 25 - Expediente 23-2 / N de pg.: 1 (mecanografiada)

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Fecha: 29-9-1947 / Unidad de instalacin: Carpeta 25 - Expediente 23-4 / N de pg.: 1 (mecanografiada)

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Fecha: 1974 / Unidad de instalacin: Carpeta 48 - Expediente 8-6 / N de pg.: 3 (mecanografiadas)

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Fecha: 26/27-5-1939 / Unidad de instalacin: Carpeta 45 - Expediente 2-8 / N de pg.: 4 (mecanografiadas)

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Fecha: 21-3-1940 (>1970 copia) / Unidad de instalacin: Carpeta 45 - Expediente 2-14 / N de pg.: 4 (mecanografiadas)

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Background: Few studies have analyzed predictors of length of stay (LOS) in patients admitted due to acute bipolar manic episodes. The purpose of the present study was to estimate LOS and to determine the potential sociodemographic and clinical risk factors associated with a longer hospitalization. Such information could be useful to identify those patients at high risk for long LOS and to allocate them to special treatments, with the aim of optimizing their hospital management. Methods: This was a cross-sectional study recruiting adult patients with a diagnosis of bipolar disorder (Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision (DSM-IV-TR) criteria) who had been hospitalized due to an acute manic episode with a Young Mania Rating Scale total score greater than 20. Bivariate correlational and multiple linear regression analyses were performed to identify independent predictors of LOS. Results: A total of 235 patients from 44 centers were included in the study. The only factors that were significantly associated to LOS in the regression model were the number of previous episodes and the Montgomery-sberg Depression Rating Scale (MADRS) total score at admission (P < 0.05). Conclusions: Patients with a high number of previous episodes and those with depressive symptoms during mania are more likely to stay longer in hospital. Patients with severe depressive symptoms may have a more severe or treatment-resistant course of the acute bipolar manic episode.

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[ES] Este trabajo se encuadra dentro de los estudios centrados en el anlisis del comportamiento de compra del consumidor en Internet. Nos centramos en la adaptacin del modelo de la jerarqua de efectos basado en su variante de la jerarqua estndar de aprendizaje para proponer tericamente un modelo conceptual que explica cmo las creencias i.e. diseo, velocidad de interaccin, beneficios sociales y privacidad y actitudes del consumidor hacia Internet, como medio de comunicacin, pueden considerarse como determinantes plausibles de la confianza en la compra online. Asimismo, en nuestro modelo se plantea que las opiniones del consumidor respecto a la compra a distancia tambin deben ejercer una influencia sobre sus valoraciones de Internet, como medio de comunicacin y, especialmente, de compra.

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[ES] Estudio de caso (Fiesta de S. Francisco en Pamplona, Navarra) del modo en que la derecha conservadora espaola (Bloque de Derechas) y los radicales (carlistas) emplearon densos elementos identificadores (identidad) de lo local (Navarra-Espaa) y catlica para generar actitudes y adhesiones polticas antirrepublicanas.

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Dedicated to Prof. Julio Alvarez-Builla on the occasion of his 65th anniversary.

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8 cartas y 3 tarjetas (mecanografiadas y manuscritas) ; entre 220x280mm y 190x74mm. Ubicacin: Caja 1 - Carpeta 2

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The role of Na+ fluxes through voltage-gated sodium channels in the regulation of sperm cell function remains poorly understood. Previously, we reported that several genes encoding voltage-gated Na+ channels were expressed in human testis and mature spermatozoa. In this study, we analyzed the presence and function of the TTX-resistant VGSC a subunit Na(v)1.8 in human capacitated sperm cells. Using an RT-PCR assay, we found that the mRNA of the gene SCN10A, that encode Na-v1.8, was abundantly and specifically expressed in human testis and ejaculated spermatozoa. The Na-v1.8 protein was detected in capacitated sperm cells using three different specific antibodies against this channel. Positive immunoreactivity was mainly located in the neck and the principal piece of the flagellum. The presence of Na-v1.8 in sperm cells was confirmed by Western blot. Functional studies demonstrated that the increases in progressive motility produced by veratridine, a voltage-gated sodium channel activator, were reduced in sperm cells preincubated with TTX (10 mu M), the Na-v1.8 antagonist A-803467, or a specific Na-v1.8 antibody. Veratridine elicited similar percentage increases in progressive motility in sperm cells maintained in Ca2+-containing or Ca2+-free solution and did not induce hyperactivation or the acrosome reaction. Veratridine caused a rise in sperm intracellular Na+, [Na+](i), and the sustained phase of the response was inhibited in the presence of A-803467. These results verify that the Na+ channel Na-v1.8 is present in human sperm cells and demonstrate that this channel participates in the regulation of sperm function.